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Dental Anesthesia Market Research Report Information by Product Type (Lidocaine, Mepivacaine, Prilocaine, Bupivacaine 0.5% with epinephrine1:200,000, Articaine and Others), by Mode of Administration (Maxillary, Mandibular and Others) by Technique (Local Infiltration, Field Block and Nerve Block), by Duration of Action (Short, Medium and Long), by End User (Hospital Clinics, Clinics and Other), by Distribution Channel (Pharmacies And Drug Stores, E-Commerce and Other) and Region (Americas, Europe, Asia-Pacific, and Middle East & Africa)—Fore

ID: MRFR/Pharma/0271-CR | 110 Pages | Author: Rahul Gotadki| November 2022

Global Dental Anesthesia Market Overview

The dental anesthesia market is expected to reach USD 3.08 Billion by 2032 at 5.8% CAGR during the forecast period 2024-2032. Anesthesia is a drug, which is used for inducing sensation loss. Additionally, these drugs are unlike analgesics or painkillers that are helpful for pain relief without causing sensational loss. The dental anesthesia market is growing rapidly due to the growing geriatric population, increasing prevalence of various dental diseases, and the introduction of new products by the key players and manufacturers. Along with that, the growth of the dental anesthesia market is getting affected due to the availability of skilled anesthesiologists and the strict regulatory guidelines by various regions. However, dearth of skilled anesthesiologists might hamper the market growth to some extent.

Dental Anesthesia Market Overview

Impact of COVID-19

The pandemic spread has negatively impacted the dental anesthesia market. According to the North American Dental Group survey, nearly 71% of the participants were unwilling to visit their dentist for non-emergency care due to the COVID-19 concerns. Further, many countries had declared a halt to elective procedures like dental treatments. Countries and various industries were trying to deal with the challenges thrown up by the novel coronavirus (COVID-19). One such industry surrounded by the uncertainty of the impact of COVID-19 was the dental industry. Dental surgeons were at the highest risk of contracting and transmitting the coronavirus, alongside paramedics, nurses, and other healthcare workers. Thus, owing to these conditions, the Dental clinics across the globe were shut for a few months during the lockdowns. Many countries around the globe made the necessary decision to cancel non-emergency surgical procedures, including dental surgeries, to free up personnel and resources to care for COVID-19 patients. These factors promoted to negative impact on the market in terms of growth, revenue, and consumption.

Moreover, the COVID-19 pandemic also affected the trade of major dental anesthesia drug manufacturers worldwide. Many countries across all regions have reported an overall shortage of various drugs, including anesthetics. Additionally, there have been severe disruptions to the global economy, including major companies in the dental anesthesia market, due to the COVID-19 outbreak. Moreover, governmental mitigation strategies, shelter-in-place orders, restrictions on travel, and social distancing have led to an economic slowdown.

Also, the COVID-19 pandemic has impacted the production scenario globally. It has changed the business environment for numerous organizations across the globe. The governments of various countries canceled non-emergency surgeries during the pandemic. During the pandemic, the number of dental surgeries was reduced. This resulted in decreased demand for dental anesthesia in the market.

Dental Anesthesia Market Trends


  • High prevalence of dental diseases

Dental diseases pose a major health burden for many countries around the globe and affect people throughout their lifetime, causing pain, discomfort, and disfigurement. For instance, according to WHO, in 2020, the oral disease affected nearly 3.5 billion people worldwide. ). Similarly, according to the Centers for Disease Control and Prevention, in the US data collected between 2015 and 2018, the percent of adults aged 20–44 with untreated dental caries was 25.9%, and the percent of children aged 5–19 with untreated dental caries was 13.2%. Periodontal disease, also known as gum disease, is mainly the result of infections and inflammation of the gums and bones surrounding and supporting the teeth. According to the WHO, in 2020, severe periodontal (gum) disease affected almost 10% of the global population. The increasing prevalence of such dental issues is accelerating the demand for oral screening and surgeries around the globe, further creating a demand for dental anesthesia. This is driving the global dental anesthesia market.

  • Increasing trend towards dental health check-up

  • Growing geriatric population worldwide


  • Dearth of skilled anaesthesiologists

Anesthesia is a vital medical specialty provided by highly skilled professionals such as certified registered nurse anesthetists (CRNAs) and anesthesiologists (ANs). Anesthesiologists evaluate, monitor, and supervise patient care before, during, and after surgery while delivering anesthesia. There is a shortage of skilled anesthesiologists across the globe. According to the Association of American Medical Colleges (AAMC), around 38,000 to 124,000 physicians are expected to be needed by 2034, with roughly 12,500 of them being anesthesiologists. Moreover, it is estimated that there are billions of people around the globe who lack access to safe surgery for various reasons, including the lack of trained anesthesia providers. People living in developing and developing countries have the fewest specialists who unduly affect their health care.  The shortage of anesthesiologists affects dental screening and treatment throughout the globe. Hence, the shortage of skilled anesthesiologists is hampering the global dental anesthesia market.


  • Introduction of new dental anesthesia products

The introduction of new dental anesthesia products into the market is creating opportunities for players involved in the dental anesthesia market. The new technologically advanced dental products are used for superior patient care as well as to add comfort to professional practice. These advancements in products are making dental procedures faster and easier. For instance, in May 2017, Cetylite Inc. designed a new flavor of one of its flagship products, Cetacaine Topical Anesthetic Gel. Cetacaine aimed to feature a cool mint-flavored gel for oral anesthetic applications. It is primarily used to control pain and ease discomfort at the application site.

Supply Chain Analysis

The global market's supply chain analysis comprises five major components that start with the R&D and designing, manufacturing, distribution, marketing & sales, and post-sales monitoring.

In R&D process, new drug designs are introduced to enhance product quality and mix them with advanced compositions. As there are a variety of products available in the market, many companies are investing in R&D for high-quality drug offerings. R&D is a brainstorming process and requires sound knowledge and skills. After the R&D is over, the developers start manufacturing dental anaesthesia based on the inputs. The stage is characterized by primarily four steps — conceptualization, product designing, product development, and testing to ensure quality standards. The cost of this process can be reduced by finding substitutes for the raw material or by modifying the conventional manufacturing process.

Manufacturing is a fast process, which is followed by the testing of the product. After this, distribution, marketing & sales is the most crucial part of the supply chain. Distribution includes intermediaries, direct selling, online channels, and others. To increase awareness in the market, the leading players are conducting seminars and sessions, which give dental practitioners an idea about the availability of the new refined products. For this, a company's marketing and sales strategies play a crucial role in understanding the characteristics of the industry in which it is competing. The companies operating in the market are more inclined toward creating a subsidiary in a new region for better product reach and availability.

And lastly, post-sales monitoring plays a very important role in this market. As the global market is competitive and patient-centric, post-sales monitoring is a must to understand product performance.

Dental Anesthesia Market Segment Insights

The global dental anesthesia market is segmented into product type, mode of administration, technique, duration of action, end user and distribution channel.

Dental Anesthesia Product Type Insights

Global Dental Anesthesia Market Share (%), by Product TypeDental Anesthesia Market Share (%), by Product Type, 2020Source: MRFR Analysis


Lidocaine is the most used anesthetic in dental surgeries and procedures, which is further bifurcated into lidocaine 2% with epinephrine 1:100,000, lidocaine 2% with epinephrine 1:50,000, and lidocaineonly. Leading market players are developing cost-effective and painless administration of anesthetics, boosting the dental anesthetics market. The global dental anesthetics market is expected to introduce high-quality and efficient products in the upcoming years owing to great number of research activities funneled in the same. Further, advanced dental anesthetics have enabled healthcare professionals to perform complicated surgeries without compromising patients’ preference for minimal pain. These factors promote the growth of the market segment.


Mepivacaine is an anesthetic that blocks the nerve impulses that send pain signals to the brain. Further, the market segment is bifurcated into mepivacaine 2% with levonordefrin 1:20,000 and mepivacaine 3%. The market product gains major consumption owing to the usage in local anesthesia for dental procedures by infiltration or nerve block in adults and pediatric patients. It is also used as an anesthetic for the epidural or spinal block.


Prilocaine is a toluidine derivative and intermediate-acting amino amide with the local anesthetic property. It is further bifurcated into prilocaine 4% with epinephrine 1:200,000 and prilocaine 4%. Prilocaine support the neuronal membrane by preferential and inhibiting depolarization of voltage-gated sodium channel. This decreases membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses.

Bupivacaine 0.5% with epinephrine1:200,000

Bupivacaine is a local anesthetic drug that has been used in various dental surgical procedures. This helps block the nerve impulses that send pain signals to the brain. According to the Universities and College Admissions Service (UCAS), there has been a 13.2% increase in admissions for surgical procedures. The most common surgical procedures are hip replacement, knee replacement, hernia repairs, tonsillectomies, and gall bladder removal. Bupivacaine is used as local anesthesia due to its efficacy in numbing organs.


Articaine represents the first and only local anesthetic developed specifically for dentistry. Articaine drug is further bifurcated into articaine 4% with epinephrine 1:100,00 and articaine 4% with epinephrine 1:200,000. Though articaine is classified as an amide LA, articaine possesses chemical characteristics of both the amide and ester groups. Articaine was the second-most used local anesthetic in the US with a 34.86% market share (lidocaine was first at 49.35%). In Australia, 70% of dentists use articaine. According to PubMed, in the 2021 market share of nearly 98%, articaine was Germany's first-line local dental anesthetic agent. Articaine is being used increasingly by the medical profession. However, the clinical preparations of articaine in North America 4% with 1:100,000 and 1:200,000 epinephrine are classified as intermediate duration local anesthetics.


The other segment includes ropivacaine and chloroprocaine. Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain. It is used as a local anesthetic for mandibular nerve blockage in dentistry. Like other local anesthetics, chloroprocaine blocks the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, slowing the propagation of the nerve impulse, and reducing the rate of rising of the action potential.

Dental Anesthesia Mode of Administration Insights


The maxillary anesthesia is used to anesthetize the posterior superior alveolar nerve before it enters the posterior surface of the maxilla while it is in the infra-temporal fossa infra. It also helps to anesthetize the pulp, investing structures, and buccal mucoperiosteum of the maxillary molars except for the mesiobuccal root of the first molar. It is bifurcated into supraperiosteal injection, intraseptal injection, periodontal ligament injection, and periapical injection.


Mandibular block anesthesia plays an important role in providing profound anesthesia to the mandible. It is divided into IAN, akinosi, gow-gates, and tissue or skin. Several several mandibular blocks have been developed to provide profound anesthesia without the technical challenges of completing successful mandibular blocks.


The others segment includes intraseptal injection and field block. The growing application areas of dental anesthesia for dental diseases increase the market size for other segments. Intraseptal is a useful adjunct to the techniques. Although it is not used as often in clinical practice, the technique still provides the added advantage of hemostasis in the injection area.

Dental Anesthesia Technique Insights

Local infiltration

Local infiltration (also known as supraperiosteal injection) is one of the most used techniques for achieving anesthesia of the maxillary dentition. This technique is indicated when an individual tooth is to be treated.

Field Block

Field block indicates when an individual tooth or a specific isolated area requires anesthesia. It is performed within the direct vicinity of the site of infiltration. It also helps to anesthetize the terminal nerve branches in the treatment area. It is used for the longer duration of anesthesia and flexibility to accommodate the clinical situation.

Nerve Block

A nerve block is an anesthetic injection targeted toward a certain nerve or a group of nerves for treating pain. The purpose of the injection is to turn off a pain signal coming from a specific location in the body. The extent of the operative area determines the type of injection administered for a given treatment. Therefore, posterior superior alveolar, middle superior alveolar, and anterior superior alveolar are different types of nerve blocks.

Dental Anesthesia Duration of Action Insights


Local anesthetics vary in their duration of action due to primarily differences in their affinity for protein. Like most drugs, local anesthetics reversibly bind to plasma proteins while circulating in the bloodstream. For example, lidocaine is the most used local anesthetic in the US.


The medium duration of anesthesia is influenced by the time a local anesthetic remains near neural fibers. Topical or local infiltration administration of Articaine proved to be sufficient for dental procedures requiring anesthesia with a short to intermediate duration of action and fast onset. Articaine is the second most popular local dental anesthetic drug in the US, currently holding a major share of the US region


Prolonged duration local anesthesia requires maintaining high (therapeutic) drug concentrations at the nerve over an extended period without excessive systemic levels. The longer duration of anesthesia offered by bupivacaine is a chemical analog of mepivacaine with high lipid-solubility and protein-binding characteristics. These properties contribute to bupivacaine's greater potency and anesthetic duration than other local anesthetics used in dentistry.

Dental Anesthesia End user Insights

Hospital clinics

The dramatic rise in tooth restoration is attributed to the increasing number of tooth infections and disorders. This is because hospital clinics provide patients with dental restorations in a single visit. The health care system for the geriatric population is considered a major concern within the health care sector.


Dental anesthetics continue to witness lucrative opportunities worldwide on the backdrop of the increasing number of surgery centers and clinics worldwide. Moreover, the growth in the healthcare industry is likely to influence the dental anesthetics market squarely. Dental anesthetics are being adopted by dental clinics such as Mayo Clinic Dentistry and UCSF Dental Center due to the growing demand for painless surgeries.


The others category includes dental laboratories, research centers, and ambulatory surgical centers. A dental laboratory is a prime place where most advanced procedures are conducted. The dentist provides detailed prescribes to the dental laboratory for the final treatment of choice and placement of restoration or corrective device in the patient’s jaws. In these labs, a dental technician helps the dentist make material choices and case design the anesthesia on the patient

Dental Anesthesia Distribution Channel Insights

Pharmacies & Drug Store

Many drug stores across the globe maintain an internal pharmacy to support the patients and their family members. The increasing number of individuals, chain pharmacies, and drug stores also supports dental anesthesia sales. Pharmacies and drug stores are expected to hold a substantial market share due to the availability of medical experts such as dermatologists and neurologists, cancer specialists, and hospital accessibility.


An e-commerce or online pharmacy is a store that sells pharmaceutical preparations such as non-prescription and prescription drugs over the internet and through the mail. As the digital world expands and online technologies and consumer-friendly online experiences emerge, the business is shifting towards to direct-to-patient model. The convenience and familiarity of online purchasing have prompted many patients to seek virtual care medications and wellness options.


The others segment includes include retail pharmacies. The retail pharmacies segment is expected to register a significant CAGR during the forecast period due to improvements in medical infrastructure, an increase in the number of middle-class households, and greater penetration of health insurance.

Dental Anesthesia Regional Insights

The global dental anesthesia market has been segmented, based on region, into North America, Europe, Asia-Pacific, and the Rest of the World.

Global dental anesthesia market Share (%), by Region, 2023dental anesthesia market Share (%), by Region, 2020Source: MRFR Analysis


Americas hold the largest market share with 41.1% in 2020. The key factors attributed to the region’s large share include developed healthcare infrastructure, an increasing number of dental care procedures, and the presence of many market players in the region. According to the report published by PLOS in January 2022, dental care procedures performed in Brazil’s oral health teams (OHTs) include root planning, supragingival scaling, and coronal polishing (98.1%), permanent tooth extraction (98.6%), and composite filling (99.0%). In addition, 12.9% of the OHTs in Brazil carries out biopsies, 15.1% carry out impression for prostheses, 30.9% monitor patients undergoing a biopsy, and 13.6% carry out prostheses’ installation.


Oral diseases constitute a major public health burden across Europe. The most frequent oral diseases registered in the region include dental caries (cavities), periodontal (gum) disease, oral cancer, oral infectious diseases, trauma from injuries, and hereditary lesions. The increasing prevalence of oral diseases, advancements in medical technology, growing elderly population, and increasing demand for oral care procedures & cosmetic dentistry is driving the market growth in Europe. For instance, 23 million root canal treatments are performed every year in the EU. Dental anesthetics are being adopted in the region due to the rise in demand for painless surgeries and operations.


Oral diseases and conditions such as periodontal diseases, dental caries, malocclusion, Oro-facial anomalies, dental fluorosis, loss of teeth, dental trauma, temporomandibular joint disorders, and oral cancers affect the Asian population. This, in turn, is increasing the demand for newly formulated dental anesthesia to treat different dental disorders. Dental caries is one of the major causes of discomfort, pain, and absenteeism from school and office work in the region. According to the Ministry of Health and Family Welfare (India), dental caries affects about 60%, and periodontal diseases affect about 85% of the Indian population.

Middle east & Africa

Middle East & Africa accounted for the lowest market share in the dental anesthesia market. This is attributed to less availability of funds, expensive and unaffordable dental care, and limited medical facilities in the region. In addition, little or no access to proper oral health care and the availability of few dentists is further leading to low market growth. For instance, as per National Center for Biotechnology Information (NCBI), the dentist to population ratio is approximately 1:150,000 in Africa compared to around 1:2,000 in most industrialized countries.

Competitive Landscape

The global dental anesthesia market is characterized by the presence of many global, regional, and local vendors. The market is highly competitive, with all the players competing to gain market share. Intense competition, frequent changes in government policies, and environmental regulations are key factors that confront market growth. The vendors compete based on cost, quality, and reliability. The major players have adopted a strategy of obtaining regulatory approval from government agencies for their products and signing contracts and agreements to broaden their reach and reduce operational costs. For instance, in July 2021, Septodont acquired Sanofi’s four dental care brands, Ultracain, Rodogyl, Birodogyl, and Dontisolon. This acquisition aims to strengthen its product offerings.

For instance, Dentsply Sirona is a US-based key player in the dental anesthesia market and the world’s largest manufacturer of professional dental products and technologies. It develops, manufactures, and markets a complete dental and oral health product line, including general dental supplies and devices, CAD/CAM restoration systems (CEREC and inLab), and dental specialty products in orthodontics, endodontics, and implants. Polocaine (3% Mepivacaine HCI), and 4% Citanest Forte Dental with Epinephrine 1:200,000 are some of the anesthesia products.

Key Players

The prominent players in the global dental anesthesia market are Dentsply Sirona (US), Septodont, Inc. (France), AstraZeneca (UK), Primex Pharmaceuticals (Europe), 3m (US), Centrix, Inc (US), Cetylite, Inc (US), Crosstex International, Inc. (US), Dmg America (US), Henry Schein, Inc. (US), Patterson Companies, Inc. (US), Pierrel SPA (Italy).

Recent Developments

  • In July 2021, Septodont acquired Sanofi’s four dental care brands Ultracain, Rodogyl, Birodogyl and Dontisolon. This acquisition was done to strengthen the parent company’s product offerings.

  • In July 2019, OGNA expanded its market in Europe. This expansion aims to provide the product offering of the company in Europe region.

  • In January 2018, Cetylite announced the launch of Cetacaine topical anaesthetic spray in a single-patient package. The single-patient spray eliminates the threat of cross-contamination caused by multiple patient usages. Moreover, Bar Code Medication Administration (BCMA) inclusion further enhances accuracy, averts medication errors, and improves efficiency.

Report Overview

The study covers the existing short-term and long-term market effects, helping decision-makers draft short-term and long-term plans for businesses by region. The report covers major regions in North America, Europe, Asia-Pacific, and the Rest of the World. The report analyzes market drivers, restraints, opportunities, challenges, Porter's Five Forces, value chain, and impact of COVID-19 on the market.

Dental Anesthesia Market Segmentation

Dental Anesthesia Product Type Outlook

  • Lidocaine

  • Mepivacaine

  • Prilocaine

  • Bupivacaine 0.5% with epinephrine1:200,000

  • Articaine

  • Others

Dental Anesthesia Mode of Administration Outlook

  • Maxillary

  • Mandibular

  • Others

Dental Anesthesia Technique Outlook

  • Local Infiltration

  • Field Block

  • Nerve Block

Dental Anesthesia Duration of Action Outlook

  • Short

  • Medium

  • Long

Dental Anesthesia End User Outlook

  • Hospital Clinics

  • Clinics

  • Other

Dental Anesthesia Distribution Channel Outlook

  • Pharmacies And Drug Stores

  • E-Commerce

  • Other

Dental Anesthesia Regional Outlook 

  • Americas

  • North America

    • US

    • Canada

    • South America

  • Europe

    • Western Europe

      • Germany

      • UK

      • France

      • Italy

      • Spain

      • Rest of Western Europe

    • Eastern Europe

  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Rest of Asia-Pacific

  • Middle East & Africa

    • Middle East

    • Africa

Intended Audience

  • Hospitals

  • Dental Clinics

  • Research Institutes

  • Dental Software Manufacturers

  • Healthcare IT Companies

Report Attribute/Metric Details
  Market Size   2032: USD 3.08 Billion
  CAGR   5.8%
  Base Year   2023
  Forecast Period   2024-2032
  Historical Data   2020
  Forecast Units   Value (USD Billion)
  Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors and Trends
  Segments Covered   Type, Deployment, End User, and Region
  Geographies Covered   Americas, Europe, Asia-Pacific, Middle East & Africa
  Key Vendors   Dentsply Sirona (US), Septodont, Inc. (France), AstraZeneca (UK), Primex Pharmaceuticals (Europe), 3m (US), Centrix, Inc (US), Cetylite, Inc (US), Crosstex International, Inc. (US), Dmg America (US), Henry Schein, Inc. (US), Patterson Companies, Inc. (US), Pierrel SPA (Italy)
  Key Market Opportunities   • Introduction of new dental products
  Key Market Drivers   • High prevalence of dental diseases • Increasing trend towards dental health check-up • Growing geriatric population worldwide

Frequently Asked Questions (FAQ) :

Dental Anesthesia Market is expected to exhibit a strong 5.8% CAGR over the forecast period from 2024-2032.

Growing awareness about dental health and the increasing volume of dental procedures is the major driver for the Dental Anesthesia Market.

The unavailability of skilled anesthetists is a key restraint on the Global Dental Anesthesia Market.

The Americas dominate the Global Dental Anesthesia Market.

Leading players in the Global Dental Anesthesia Market include GSK, Dentsply Sirona, and Septodont, among others.

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