Connective Tissue Disease Market Overview
Connective tissue disease market share register 0.36 billion USD in 2024, projected to grow 11.48% CAGR during the forecast period (2024 - 2032). As per MRFR analysis, the connective tissue disease market industry size is expected to grow from 0.24 billion USD in 2023 to 0.52 billion USD by 2032.

Connective tissues are a group of cellular congregations that provide support and structure to the human body. Connective tissue disease is a group of disorders which involves these protein rich tissues. Protein rich tissues play an important role of supporting organs and other parts of the body. Connective tissue disorders involves multiple organs and organ systems such as, skin, joints, muscles, lungs, kidneys, eyes, heart, gastrointestinal tract, and blood vessels.Â
More than 200 disorders affect the connective tissues. According to a study published in Pan African Medical Journal in 2017, it is found that mixed connective tissue disorders are more frequent among Asians, and in the African population. It is also reported that among Asian population, the condition is more prevalent in China, and Japan. In the European region, the disorder is more prevalent in Italy, Hungary, Norway, and Poland.
The specific cause of this disorder is unknown but the genetic patterns are considered to escalate the risk for developing connective tissue diseases. The connective tissue diseases arises due to changes in certain genes are often known as heritable disorders of connective tissue. Some of the common inherited disorders are Ehlers-Danlos syndrome (EDS), Epidermolysis bullosa (EB), Marfan Syndrome, and Osteogenesis imperfect.Â
EDS is an amalgamation of more than 10 disorders, characterized by stretchy skin, over-flexible joints, and abnormal growth of scar tissue. Various autoimmune diseases are also associated with connective tissue disorders, which includes polymyositis and dermatomyositis, rheumatoid arthritis (RA), Sjögren's syndrome, and vasculitis. Mixed connective tissue disease (MCTD) is another rare autoimmune disease, consisting of characteristic features of several diseases such as lupus, polymyositis or dermatomyositis, scleroderma, and rheumatoid arthritis.Â
According to the National Center for Advancing Translational Medicines, currently there is no cure available for this condition but certain medications such as corticosteroids, immunosuppresive drugs, and nonsteroidal anti-inflammatory drugs (NSAIDs) help in the management of symptoms. It is also stated that MCTD is more frequent in females with a male to female ratio of 1:3, and the typical age of onset of MCTD is between 15-25 years.
Notably, the Connective Tissue Disease Market is expected to expand in the near future due to the rising prevalence of various connective tissue disorders, high unmet needs of current treatment, and surge in the research and development expenditure.
Despite these drivers, there are some issues associated with connective tissue disease market. Lack of infrastructure in the middle and low income countries may hamper the growth of the market.
Intended Audience
- Research and Development (R&D) Companies
- Government Research Institute
- Academic Institutes and UniversitiesÂ
Figure: Global Connective Tissue Disease Market, By Region Market Share, 2017 (%) 
Sources: Annual reports, Press release, White paper, Company presentation
Connective Tissue Disease Market Segmentation
The connective tissue disease market is segmented on the basis of diagnosis, treatment, and end-user.
On the basis of diagnosis, market is segmented into physical examination, X-ray examination, ANA (Antinuclear Antibody Test), and others.
On the basis of treatment, market is classified into non-steroidal anti-inflammatory drugs (NSAIDs), cortisone drugs/steroids, antimalarial drugs, cytotoxic drugs, and others
On the basis of end-user, market is segmented into hospital, diagnostic clinics, and others.
Connective Tissue Disease Market Regional Analysis
The Americas dominate the connective tissue disease market owing to the rising awareness among people, and increasing healthcare expenditure. As per the facts suggested by the Centers for Disease Control and Prevention (CDC), out of the total annual healthcare expenditure, 86% is for people with chronic health conditions in the United States.
Europe holds the second position in the connective tissue disease market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the Connective Tissue Disease Market in Europe.
Asia Pacific is the fastest growing Connective Tissue Disease Market, owing to a huge patient pool, developing healthcare technology, and rising healthcare expenditure in some countries within this region. According to the Australian Institute of Health and Welfare, in the years 2015 to 2016, the total health expenditure was USD 170.4 billion, which is 3.6% higher than expenditure of 2014–15.
The Middle East & Africa has the lowest Connective Tissue Disease Market due to lack of technical knowledge and poor medical facilities.Â
Connective Tissue Disease Market Industry Developments
- Q2 2024: Johnson & Johnson Announces FDA Approval of Saphnelo (anifrolumab) for the Treatment of Systemic Lupus Erythematosus Johnson & Johnson received FDA approval for Saphnelo (anifrolumab), a biologic therapy for adults with moderate to severe systemic lupus erythematosus, marking a significant addition to the treatment options for connective tissue diseases.
- Q1 2024: Roche receives European Commission approval for Enspryng in neuromyelitis optica spectrum disorder Roche announced that the European Commission approved Enspryng (satralizumab) for the treatment of neuromyelitis optica spectrum disorder, a rare autoimmune connective tissue disease, expanding its reach in the European market.
- Q2 2024: Bristol Myers Squibb Announces FDA Approval of Zeposia for the Treatment of Ulcerative Colitis Bristol Myers Squibb received FDA approval for Zeposia (ozanimod) for the treatment of ulcerative colitis, an autoimmune condition with connective tissue involvement, further strengthening its immunology portfolio.
- Q1 2024: Amgen Completes Acquisition of ChemoCentryx, Expanding Autoimmune and Inflammatory Disease Portfolio Amgen completed its acquisition of ChemoCentryx, a company focused on therapies for autoimmune and inflammatory diseases, including those affecting connective tissue, enhancing Amgen's pipeline in this sector.
- Q2 2024: GSK announces positive Phase III results for Benlysta in pediatric lupus patients GSK reported positive Phase III trial results for Benlysta (belimumab) in pediatric patients with systemic lupus erythematosus, supporting regulatory filings for expanded use in this connective tissue disease.
- Q1 2024: UCB Announces FDA Approval of Bimzelx for the Treatment of Psoriatic Arthritis UCB received FDA approval for Bimzelx (bimekizumab) for the treatment of psoriatic arthritis, an autoimmune disease with connective tissue involvement, marking a new therapeutic option for patients.
- Q2 2024: Pfizer and BioNTech Announce Strategic Collaboration to Develop mRNA-based Therapies for Autoimmune Diseases Pfizer and BioNTech entered a strategic partnership to develop mRNA-based therapies targeting autoimmune diseases, including connective tissue disorders, leveraging mRNA technology for novel treatments.
- Q1 2024: Eli Lilly Receives FDA Approval for Mirikizumab for the Treatment of Ulcerative Colitis Eli Lilly received FDA approval for Mirikizumab, a monoclonal antibody for the treatment of ulcerative colitis, an autoimmune disease with connective tissue involvement.
- Q2 2024: Regeneron and Sanofi Announce FDA Approval of Dupixent for Eosinophilic Esophagitis Regeneron and Sanofi received FDA approval for Dupixent (dupilumab) for the treatment of eosinophilic esophagitis, a chronic immune-mediated disease with connective tissue involvement.
- Q1 2024: AstraZeneca Announces FDA Approval of Fasenra for Hypereosinophilic Syndrome AstraZeneca received FDA approval for Fasenra (benralizumab) for the treatment of hypereosinophilic syndrome, a rare connective tissue disease, expanding its immunology portfolio.
Connective Tissue Disease Market Key Players
Some of key the players in the Connective Tissue Disease Market are:Â
Research Methodology

Sources: Annual reports, Press release, White paper, and Company presentation
Attribute/Metric |
Details |
 |
  Market Size |
USD 0.52 Billion |
 |
  CAGR |
 11.48 % (2024-2032) |
 |
  Base Year |
  2023 |
 |
  Forecast Period |
  2024-2032 |
 |
  Historical Data |
Market Size 2023 |
0.24 (USD Billion) |
  Forecast Units |
Market Size 2024 |
0.36 (USD Billion) |
  Report Coverage |
Market Size 2032 |
0.52 (USD Billion) |
  Segments Covered |
Compound Annual Growth Rate (CAGR) |
11.48 % (2024 - 2032) |
  Geographies Covered |
Report Coverage |
Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
  Key Vendors |
Base Year |
2023 |
  Key Market Opportunities |
Market Forecast Period |
2024 - 2032 |
  Key Market Drivers |
Historical Data |
2019 - 2023 |
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Connective Tissue Disease Market Highlights:
Frequently Asked Questions (FAQ):
connective tissue disease market is projected to grow at approximately 11.48% CAGR during the assessment period (2024-2032).
Rising prevalence of the condition, high unmet needs of current treatment, and increase in R&D expenditure are major tailwinds pushing the growth of the global connective tissue disease market.
Lack of infrastructure in the middle and low income countries are major growth impeders for the global connective tissue disease market.
North America holds the largest share in the global connective tissue disease market, followed by Europe and the Asia Pacific, respectively.
Abbott Laboratories, F. Hoffmann-La Roche Ltd, Bayer AG, Pfizer, Johnson & Johnson, AutoImmune Inc., Amgen Inc., Eli Lilly and Company, AstraZeneca, Biogen, and LUPIN, are some of the top players operating in the global connective tissue disease market.