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Calciphylaxis Market Share

ID: MRFR//2425-CR | 152 Pages | Author: Kinjoll Dey| August 2017

The treatment of calciphylaxis faces a significant challenge as there is currently no specific remedy available in the market. The existing treatment methods are not proving to be effective, creating a notable opportunity for manufacturers to explore the development of new drugs. This gap in treatment options presents a potential avenue for growth, particularly in developing countries where there is a focus on encouraging research and development in the management of wounds. Consequently, the creation of novel drugs has the potential to become a lucrative source of revenue, contributing to the expansion of the market.

One crucial aspect of advancing treatment options for calciphylaxis involves research and development (R&D) initiatives. Key players in the calciphylaxis market are actively engaging in continuous R&D activities to formulate targeted treatments for this challenging disease. The combination of unmet market needs and promising growth prospects has motivated industry participants to invest in R&D, aiming to produce innovative drug candidates. For instance, Sanifit, a notable player in the market, has achieved a milestone by successfully completing phase IIb clinical trials for its drug SNF472, initially designed for cardiovascular disease. Currently, this drug is progressing through phase II/III trials specifically for calciphylaxis.

The landscape of calciphylaxis treatment is marked by a lack of effective solutions, emphasizing the urgency for new and innovative drugs. The commitment of key industry players to ongoing research and development underscores the recognition of this need. As these efforts progress, there is a growing anticipation that breakthroughs in drug development will not only address the unmet needs of patients but also contribute significantly to the overall growth of the market.

The potential for growth is particularly pronounced in developing countries, where concerted efforts are being made to foster research and development in the field of wound care management. The encouragement of such initiatives opens up new avenues for manufacturers to introduce innovative drugs, catering to the specific needs of patients with calciphylaxis. This aligns with a broader trend of global collaboration in addressing healthcare challenges, with a particular focus on diseases that lack effective treatment options.

Sanifit's progress in advancing SNF472 through clinical trials exemplifies the dedication to finding solutions for calciphylaxis. The transition from phase IIb trials for cardiovascular disease to phase II/III trials for calciphylaxis reflects a strategic response to the pressing need for effective treatments in this domain. Success in these trials could mark a significant milestone not only for Sanifit but for the entire industry, offering hope for improved outcomes and quality of life for individuals affected by calciphylaxis.

In conclusion, the development of innovative drugs for calciphylaxis is a crucial frontier in healthcare, driven by the lack of specific and effective treatments. The ongoing research and development activities, exemplified by initiatives such as Sanifit's clinical trials, highlight the industry's commitment to addressing this unmet medical need. As these efforts progress, there is a potential for transformative breakthroughs that not only enhance patient care but also contribute to the growth of the market, particularly in regions actively promoting research and development in wound care management.

Covered Aspects:

Report Attribute/Metric Details
Base Year For Estimation 聽聽2021聽聽Forecast Period聽聽2023-2032聽聽Historical Data聽聽2020聽聽Forecast Units聽聽Value (USD Million)聽聽Report Coverage聽聽Revenue Forecast, Competitive Landscape, Growth Factors, and Trends聽聽Segments Covered聽聽Diagnosis, Treatment, and End user聽聽Geographies Covered聽聽North America, Europe, Asia-Pacific, and Rest of the World (RoW)聽聽Key Vendors聽聽Amgen Inc., Smith & Nephew plc, Medtronics, 3M, BSN Medical, ConvaTec Inc, Sanifit, and others聽聽Key Market Opportunities聽聽New product launches and R&D Amongst major key Players聽聽Key Market Drivers路聽 Increasing prevalence of cardiovascular calcification in ESRD patients路聽 Increasing healthcare expenditure路聽 Rising research & development activities路聽 Awareness among patients about the treatment options聽
Historical Data 2020 Forecast Units Value (USD Million) Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends Segments Covered Diagnosis, Treatment, and End user Geographies Covered North America, Europe, Asia-Pacific, and Rest of the World (RoW) Key Vendors Amgen Inc., Smith & Nephew plc, Medtronics, 3M, BSN Medical, ConvaTec Inc, Sanifit, and others Key Market Opportunities New product launches and R&D Amongst major key Players Key Market Drivers路 Increasing prevalence of cardiovascular calcification in ESRD patients路 Increasing healthcare expenditure路 Rising research & development activities路 Awareness among patients about the treatment options
Forecast Period 聽聽2023-2032聽聽Historical Data聽聽2020聽聽Forecast Units聽聽Value (USD Million)聽聽Report Coverage聽聽Revenue Forecast, Competitive Landscape, Growth Factors, and Trends聽聽Segments Covered聽聽Diagnosis, Treatment, and End user聽聽Geographies Covered聽聽North America, Europe, Asia-Pacific, and Rest of the World (RoW)聽聽Key Vendors聽聽Amgen Inc., Smith & Nephew plc, Medtronics, 3M, BSN Medical, ConvaTec Inc, Sanifit, and others聽聽Key Market Opportunities聽聽New product launches and R&D Amongst major key Players聽聽Key Market Drivers路聽 Increasing prevalence of cardiovascular calcification in ESRD patients路聽 Increasing healthcare expenditure路聽 Rising research & development activities路聽 Awareness among patients about the treatment options聽
Growth Rate 聽聽11.3%聽聽Base Year聽聽2021聽聽Forecast Period聽聽2023-2032聽聽Historical Data聽聽2020聽聽Forecast Units聽聽Value (USD Million聽聽Report Coverage聽聽Revenue Forecast, Competitive Landscape, Growth Factors, and Trends聽聽Segments Covered聽聽Diagnosis, Treatment, and End user聽聽Geographies Covered聽聽North America, Europe, Asia-Pacific, and Rest of the World (RoW)聽聽Key Vendors聽聽Amgen Inc., Smith & Nephew plc, Medtronics, 3M, BSN Medical, ConvaTec Inc, Sanifit, and others聽聽Key Market Opportunities聽聽New product launches and R&D Amongst major key Players聽聽Key Market Drivers路聽 Increasing prevalence of cardiovascular calcification in ESRD patients路聽 Increasing healthcare expenditure路聽 Rising research & development activities路聽 Awareness among patients about the treatment options聽

Calciphylaxis Market Overview

The Calciphylaxis Market size is expected to reach USD 5.4 Billion by 2032 at 11.3% CAGR during the forecast period 2023-2032. Calciphylaxis or Calcific Uremic Arteriolopathy is the severe form of cardiovascular calcification in a dialysis patient. It first starts with the calcification of a small peripheral vessel and then spreads quickly all over the body. People suffering from calciphylaxis usually have calcium imbalance metabolism, which causes a deposit of calcium in the arterioles which eventually leads to the creation of blood clots in the arterioles. Blood clots cause fat tissues and lack of nourishment, and oxygen deprivation in the skin.


According to the report by NCBI, calciphylaxis affects around 4% of patients in the last stage of chronic kidney diseases, and almost 55% of people who are affected by calciphylaxis die within a year of diagnosis as they suffer from painful skin ulcers. There is a high risk of infection. There are no effective treatments found to date, and its cause is unknown. The patients suffering from this disease are treated with intensive care, including management of the wound. The occurrence of calciphylaxis is related to hyperthyroidism.


Covid-19 analysis


The sudden covid outbreak has resulted in some strict government regulation across the world, resulting in the breakage in the import and export activities of calciphylaxis treatment. Covid-19 has affected the economy globally in three main ways as by directly affecting production and demand, by creating supply chains and market breakage, and at last by financially impacting on the firms and financial markets. According to聽Calciphylaxis Market Analysis, the situation all around the globe explains that the market will create remunerative prospects for the producers' post covid crisis.聽


Chief Factors Existing In The Market



  • Key Market Drivers


As the commonness of cardiovascular calcification in ESRD patients is increasing at a rapid pace, the聽Market聽is increasing at the same pace. The second most important factor that drives the聽Market is聽increasing healthcare expenditure; as the disease is increasing, the expenditure is also increasing. The sudden rise in聽research & development activities is also one of the major reasons behind the market growth.聽The more people get aware of the disease, the more they will opt for treatment, so聽awareness among patients about the treatment options is another key driver for聽Calciphylaxis Market growth.



  • Market Challenges


Expensive Calciphylaxis Treatment


This is the major factor that is reflected as a challenge in the聽Market.聽The high cost of the treatments will hamper the聽Calciphylaxis Market Value.聽As it is expensive, most of the population will face a crisis to afford it. This results in affecting the聽market.


There is a high risk of infection.


The people who are affected by calciphylaxis die within a year of diagnosis as they suffer from painful skin ulcers, and there is a high risk of infection. There are no effective treatments found to date, and its cause is unknown.



  • Market Opportunities


Hyperparathyroidism, along with dysregulation in calcium and phosphorous metabolism, is the major risk factor in calciphylaxis. The multi-disciplinary approach is adopted that spans nephrology, dermatopathology, dermatology, pain management and nutrition. These are the key factors that will drive the rapid evolution of the calciphylaxis treatment market. The rapidly growing number of clinical trials will have a definite positive influence on the growth of the market in the future. Whereas the randomized controlled trials for the management of calciphylaxis still lack. The collaboration of the companies is growing, with research institutes helping in the growth of the clinical trials in several places.聽


The rise in the economic burden of dialysis on the health system globally is an important factor that signs well for the market. The rise in the commonness of kidney and end-stage renal diseases is a major factor that causes the demand for better calciphylaxis treatment which will bring down the repeating hospitalization and reduce morbidity. The rise in the healthcare budget for the treatment of chronic kidney disease is another major factor.



  • Market Restraints


The lack in the treatment of calciphylaxis is the major factor that is affecting the聽Calciphylaxis Market Share聽and growth globally. As there is no effective treatment method available till now, it is affecting the market. The increasing research to find the suitable treatment for the disease is somehow driving the market.


Cumulative Evaluation Of The Market


With high data integrity and industry-standard accuracy in analysis, it makes a brilliant attempt to unveil key opportunities available in the market聽to help players in achieving a strong market position. Buyers of the report can access verified and reliable market forecasts, including those for the overall size of the聽Calciphylaxis market聽globally in terms of revenue.


Market Segmentation


The聽calciphylaxis market聽is divided on the basis of diagnosis, treatment, and end-user.


Under the diagnosis, the market is further segmented into deep skin biopsies, imaging, blood tests and others. Deep skin biopsies are further divided into shave biopsy, excisional biopsy and punch biopsy. The blood tests are further divided into serum parathormone levels, blood urea nitrogen, calcium levels, blood glucose levels and others. Imaging is further divided into magnetic resonance imaging, ultrasound, CT scan, and others.


Under the applications, the聽calciphylaxis market聽is divided into intensive wound care, clot-dissolving, medication, therapy, and others. The intensive wound care unit is again divided into debridement, wet dressings, and others. Medication is again divided into cinacalcet, sodium thiosulfate, bisphosphonates and steroids.


Under the end-user, the聽market聽is divided into hospitals, clinics, medical research centers, academic institutes, and others.聽


Regional Analysis


The聽calciphylaxis market聽is dominated by America owing to the huge development in the healthcare domain, presence of the strong economic condition, and focus of research institutions on updating new versions of technology for new and advanced treatment methods. Moreover, advanced hospitals infrastructures and the availability of skilled healthcare professionals are further adding fuel to the growth of the market.聽


Europe holds the rank of second in the聽calciphylaxis market聽on the basis of changing lifestyle, increasing emphasis on rapid diagnosis and treatment of diseases, increasing commonness of diseases among the senior population.聽


The Asia Pacific is the fastest growing聽calciphylaxis market聽on the basis of more number of developing nations present in this region countries such as India and China. These countries are encouraging the growth of the healthcare field. The increasing patient population of cancer in developing countries will directly raise the demand for various diagnoses & treatment methods, which will help in boosting the market growth.


The Middle East & Africa is expected to have the least market share due to less availability of medical facilities and less development in the healthcare field. However, countries such as Qatar and Kuwait are focusing more on the healthcare field and developing medical facilities, which is estimated to raise the聽calciphylaxis market聽size聽of this region.聽


Competitive Intensity Within The Industry聽


According to the offers insights into trends and prevailing intensity of competition in the factors that can significantly change the future dynamics. It evaluates the impact of the entry of new players on the competitive market. Some of the main key players with heavy investments in the聽calciphylaxis market聽are LaboratorisSanifit S.L., Medtronic Plc., ConvaTec Inc., BSN Medical, Amgen Inc., Smith & Nephew Plc. and the 3M Company. The report says that the outcome of intense study and diligent evaluation of various dynamics shapes the growth of the market.


Recent Market Developments



  • Vifor Pharma to acquire Sanifit to further strengthen the late-stage pipeline in nephrology.

  • In the U.S., Helsinn Group and BridgeBio Pharma announced to update strategic collaboration to develop, manufacture and commercialize Infigratinib in Oncology indications.


Report Overview


This report includes the market overview, market strategy, calciphylaxis market trends, forecast, outlook聽and recent developments of the market. It shows both the opportunities and challenges of the market. The key players and how they change the market strategy.


Key Industrial Segments聽


By Treatment:



  • Drug Therapy

  • Hyperbaric Oxygen Therapy


聽By End User:



  • Hospital and Clinics

  • Homecare

  • Ambulatory Centers


聽By Region:



  • North America

  • Europe

  • the Asia Pacific

  • Latin America

  • the Middle East

  • Africa

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