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Biosurgery Market Size, Growth and Analysis by Product (Bone-Graft Substitutes, Hemostatic Agents, Soft-Tissue Attachments, and Others), Source (Biological Products, Synthetic Products), Application (Neurological Surgery and Others)‚ÄĒGlobal Forecast till 2032

ID: MRFR/MED/4785-HCR | 100 Pages | Author: Rahul Gotadki| June 2024

Biosurgery Market Overview

Global biosurgery market size was valued at USD 13.15 billion in 2022. The biosurgery market industry is projected to grow from USD 14.52 billion in 2023 to USD 34.80 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.13% during the forecast period (2023 - 2032). 

Biosurgery Market


Biosurgery products minimize intra- and postoperative complications in a variety of treatments. These cutting-edge gadgets assist physicians in operating more effectively by decreasing surgery-related problems is costly and complex operations. The global market of biosurgery is expected to develop significantly shortly as a result of increased investment, increased R&D spending, and aggressive methods used by top competitors such as new product launches. Various biosurgery products, such as hemostatic agents and surgical sealants, are increasingly being used in place of traditional sutures and staples during surgeries to control bleeding and cover the wound when using traditional goods is problematic or ineffective. The market for biosurgery solutions is being driven by a growing focus on effective blood loss management and an increase in the number of elective surgeries. Globally, growth in elective surgical procedures can be ascribed to the prevalence of lifestyle problems and chronic diseases, as well as a growing geriatric population. Furthermore, the rising prevalence of severe traumatic injuries is fueling the demand for biosurgery products as a replacement for suture and ligature-based methods. Organic growth techniques such as new releases and developments are being used by vendors, resulting in a global increase in the availability of advanced items.

Biosurgery Market Segment Insights

The global biosurgery market has been segmented on the basis of product, source, and application.

On the basis of product, the market has been classified as bone graft substitutes, hemostatic agents, soft-tissue attachments, surgical sealants and adhesives, adhesion barriers, and staple-line reinforcement agents. The bone-graft substitutes segment has been further divided into demineralized bone matrix, synthetic bone grafts, bone morphogenetic proteins, and other bone-graft substitutes. The hemostatic agents segment has been further divided into thrombin-based hemostatic agents, oxidized regenerated cellulose-based hemostatic agents, and combination hemostatic agents. The soft-tissue attachments segment has been classified as synthetic meshes and biological meshes. The surgical sealants and adhesives segment has been divided into natural and synthetic sealants and adhesives. The natural sealants sub-segment has been segmented into fibrin sealants, collagen-based sealants, gelatin-based sealants, albumin-based sealants, and other natural sealants. The synthetic sealants segment has been divided into peg hydrogels, cyanoacrylate-based sealants and adhesives, urethane-based sealants and adhesives, and others. Furthermore, the adhesion barriers segment has been sub-segmented into synthetic and natural adhesion barriers. The synthetic adhesion barriers segment includes hyaluronic acid-based, peg-based, and ther synthetic barriers. The natural adhesion barriers segment includes collagen- and fibrin-based adhesion barriers.

The biosurgery market, by source, has been segmented into biological and natural products. On basis of application, the market has been divided into neurological surgery, general surgery, cardiovascular surgery, orthopedic surgery, thoracic surgery, gynecology surgery, reconstructive surgery, and urology surgery.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The market of biosurgery in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. 

The biosurgery market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The market in the Middle East & Africa has been segmented into the Middle East and Africa.

The Americas are likely to dominate the global biosurgery market owing to the rising prevalence of chronic diseases in the aging population, increase in the number of surgical procedures, the presence of a well-established healthcare system, growing incidences of trauma-related injuries, and adoption of highly advanced technology. According to the American Association for the Surgery of Trauma, injury accounts for over 150,000 deaths and over 3 million non-fatal injuries are reported per year in the US.

The European market is expected to be the second-largest market of biosurgery. The market growth in this region can be attributed to government funding and support of the healthcare sector coupled with increasing research and development. Moreover, a growing number of surgeries due to changing lifestyles is contributing to the growth of the market in this region.

Asia-Pacific is expected to be the fastest-growing biosurgery market during the forecast period owing to the increasing prevalence of chronic diseases, rising investments in healthcare and expansions by market players in the region. For instance, in February 2014, Cryolife, Inc. established a new subsidiary in Asia-Pacific.

The market in the Middle East & Africa is expected to account for the smallest share of the global market of biosurgery due to an underdeveloped healthcare sector, lack of technical knowledge, and poor medical facilities.

Company Profiles

  • Baxter International, Inc.

  • Braun Melsungen AG

  • R. Bard

  • Johnson & Johnson

  • Medtronic, PLC.

  • MAQUET Holding B.V. & Co. Kg. (Getinge Group)

  • Cohera Medical Inc.

  • Integra Lifesciences Holdings Corporation

  • Commonwealth Serum Laboratories (CSL)

  • Hemostasis, LLC

  • Sanofi

  • Pfizer Inc.

  • Stryker Corporation

  • Cryolife, Inc.

  • Kuros Biosciences Ltd.

Research Methodology

Market Research Future analysis is conducted by industry experts who offer insight into industry structure, market segmentation, treatment assessment, competitive landscape (CL), market penetration, as well as on emerging trends. Besides primary interviews (~80%) and secondary research (~20%), their analysis is based on years of professional expertise in their respective industries. Our analysts also predict where the market of biosurgery will be headed in the next five to 10 years by analyzing historical trends and current market positions. Furthermore, the varying trends of segments and categories are studied in each region and are estimated based on primary and secondary research.

  • Primary Research

Extensive primary research was conducted to gain a deeper insight into the market and the industry performance. In this particular report, we have conducted primary surveys (interviews) with the key level executives (VPs, CEOs, marketing directors, and business development managers, among others) of the major players active in the market. In addition to analyzing the current and historical trends, our analysts predict where the market is headed over the next five to 10 years.

  • Secondary Research

Secondary research was mainly used to collect and identify information useful for an extensive, technical, market-oriented, and commercial study of the global biosurgery market. It was also used to obtain key information about major players, market classification and segmentation according to industry trends, regional markets, and developments related to the market and treatment perspectives. For this study, analysts have gathered information from various credible sources such as annual reports, SEC filings, journals, white papers, corporate presentations, company websites, international organizations of chemical manufacturers, and paid databases, among others.

Recent Development 

Peri-Strips Dry with Veritas Collagen Matrix product with Secure Grip received 510 (k) clearance from the US FDA in February 2020. This product is a staple line reinforcing agent that is used to control bleeding during bariatric and other surgical procedures. Integra LifeSciences Holdings Corp. also introduced AmnioExcel Plus Placental Allograft Membrane for soft tissue healing. Orthofix Medical Inc. (US) released the O-GENESIS Graft Delivery System and AlloQuent Structural Allograft Q-Pack, ready-to-use cervical and lumbar spacers for allograft surgeries, in October 2020. This corporation is one of the top companies in terms of market share and currently controls the market.


Biosurgery Market Segmentation


Biosurgery Product Outlook


Bone-Graft Substitutes

    • Demineralized Bone Matrix

    • Synthetic Bone Grafts

    • Bone Morphogenetic Proteins

    • Other Bone-Graft Substitutes

  • Hemostatic Agents

    • Thrombin-Based Hemostatic Agents

    • Oxidized Regenerated Cellulose-Based Hemostatic Agents

    • Combination Hemostatic Agents

  • Soft-Tissue Attachments

    • Synthetic Meshes

    • Biological Meshes

  • Surgical Sealants and Adhesives

    •   Natural Sealants and Adhesives

  • Fibrin Sealants

  • Collagen-Based Sealants

  • Gelatin-Based Sealants

  • Albumin-Based Sealants

  • Other Natural Sealants

    •   Synthetic Sealants and Adhesives

  • Peg Hydrogels

  • Cyanoacrylate-Based Sealants and Adhesives

  • Urethane-Based Sealants and Adhesives

  • Other Synthetic Sealants

  • Adhesion Barriers

    •   Synthetic Adhesion Barriers

  • Hyaluronic Acid-Based Adhesion Barriers

  • Regenerated Cellulose-Based Adhesion Barriers

  • Peg-Based Adhesion Barriers

  • Ther Synthetic Adhesion Barriers

    • Natural Adhesion Barriers

  • Collagen and Protein Adhesion Barriers

  • Fibrin-Based Adhesion Barriers

  • Staple-Line Reinforcement Agents

Biosurgery Source Outlook

  • Biological Products

  • Synthetic Products

Biosurgery Application Outlook

  • Neurological Surgery

  • General Surgery

  • Cardiovascular Surgery

  • Orthopedic Surgery

  • Thoracic Surgery

  • Reconstructive Surgery

  • Urology Surgery

Biosurgery Region Outlook

  • Americas

    • North America

      • US

      • Canada

    • South America

  • Europe

    • Western Europe

      • Germany

      • France

      • Italy

      • Spain

      • UK

      • Rest of Western Europe

    • Eastern Europe

  • Asia-Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Middle East

    • Africa

Intended Audience

  • Biosurgery product manufacturers

  • Biosurgery product distributors and suppliers

  • Healthcare providers

  • Medical device manufacturers

  • Research institutes and academic centers

  • Contract research organizations (CROs)

  • Government associations

  • Market research and consulting

Report Attribute/Metric Details
  Market Size   2032: 34.80 Billion
  CAGR   9.13% (2020-2030)
  Base Year   2021
  Forecast Period   2022-2032
  Historical Data   2020
  Forecast Units    Value (USD Billion)
  Report Coverage  Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
  Segments Covered  By Product, Source, Application,
  Geographies Covered  North America, Europe, Asia-Pacific, and Rest of the World (RoW)
  Key Vendors Baxter International, Inc., B. Braun Melsungen AG, C.R. Bard, Johnson & Johnson, Medtronic, PLC., MAQUET Holding B.V. & Co. Kg. (Getinge Group), Cohera Medical Inc., Integra Lifesciences Holdings Corporation, Commonwealth Serum Laboratories (CSL), Hemostasis, LLC, Sanofi, Pfizer Inc., Stryker Corporation
  Key Market Opportunities Increasing research, development and growing number of surgeries due to changing lifestyles is contributing to the growth of the market
  Key Market Drivers · Growing geriatric population, an increasing number of surgeries ·  Rising occurrences of trauma and sports-related injuries

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