The rising prevalence of osteoarthritis and joint disorders and growing aging population are driving the growth of the Collagen and Hyaluronic Acid Intra-Articular Injections Market at a CAGR of 6.15% during the forecast period 2025 to 2035

Market Research Future (MRFR) has published a cooked research report on the “Global Collagen and Hyaluronic Acid Intra-Articular Injections Market” that contains the information from 2019 to 2035.

The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market is estimated to register a CAGR of 6.15 % during the forecast period of 2025 to 2035.

MRFR recognizes the following companies as the key players in the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market — Seikagaku Corporation, Bioventus, Inc., Anika Therapeutics, Inc., Zimmer Biomet, Sanofi, Teva Pharmaceutical Industries Ltd., Ferring B.V., Dr. Reddy's Laboratories Ltd., Fidia Farmaceutici S.p.A., Semical Biosurgery, Avanos Medical, Inc., Maxigen Biotech Inc. (MBI) and others.

The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market accounted for registering a CAGR of 6.15 % during the forecast period and is estimated to reach USD 6.32 billion by 2035.

The rising prevalence of osteoarthritis and joint disorders is a significant driver of the global collagen and hyaluronic acid intra-articular injections market. Osteoarthritis, the most common form of arthritis, affects millions worldwide, particularly the aging population. According to the World Health Organization (WHO), osteoarthritis is one of the leading causes of disability, and its incidence is expected to rise as global life expectancy rises. According to the United Nations, more than 130 million people will have osteoarthritis by 2050, creating a significant demand for effective treatments. Joint disorders, such as rheumatoid arthritis, and sports-related injuries add to this growing burden.

Collagen and hyaluronic acid injections are commonly used to treat osteoarthritis and other joint conditions because they provide pain relief, improve joint function, and delay the need for surgical intervention. Hyaluronic acid serves as a lubricant and shock absorber in joints, whereas collagen aids in cartilage integrity. The rising prevalence of risk factors like obesity, sedentary lifestyles, and sports injuries has increased the demand for these treatments. Furthermore, the aging population, which is more vulnerable to degenerative joint diseases, is a significant demographic driving market growth.

As patients and healthcare providers become more aware of minimally invasive treatment options, collagen and hyaluronic acid injections are replacing traditional pain management methods and invasive surgeries. This trend, combined with advancements in injection technologies and formulations, position the market for long-term growth. The rising prevalence of osteoarthritis and joint disorders highlights the critical role that these injections play in improving patients' quality of life around the world.

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Segmental Analysis

The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market has been segmented based on Product Type, by Application, by Distribution Channel.

Based on Product Type, this segment includes Hyaluronic Acid Injection (Single Injection, Multiple Injection), Collagen Injection, Combination of Hyaluronic Acid and Collagen. The Hyaluronic Acid Injection segment dominated the global market in 2024, while it is projected to be the fastest–growing segment during the forecast period. Both single and multiple injection variants are popular for treating joint disorders and enhancing skin volume. This segment is also projected to be the fastest growing during the forecast period due to increasing demand for non-surgical cosmetic procedures, aging populations, and growing awareness of hyaluronic acid’s effectiveness. Technological advancements and improved formulations are further accelerating their adoption across medical and cosmetic fields, boosting market growth in the coming years.

Based on Application, this segment includes Knee Osteoarthritis, Joint Pain, Veterinary Applications, Post-Operative Recovery, Others. The Knee Osteoarthritis segment dominated the global market in 2024, while it is projected to be the fastest–growing segment during the forecast period. This segment is also projected to be the fastest growing during the forecast period, driven by increasing awareness of early intervention, rising healthcare expenditure, and the growing preference for non-surgical treatments. Additionally, advancements in injection therapies and the growing burden of osteoarthritis worldwide are expected to further propel demand, making this segment a key contributor to overall market expansion in the coming years.

Based on Distribution Channel, this segment includes Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies. The Hospital Pharmacies segment dominated the global market in 2024, while the Online Pharmacies segment is projected to be the fastest–growing segment during the forecast period. Hospital pharmacies are often the primary source for post-operative and osteoarthritis care, contributing significantly to sales volume. However, the Online Pharmacies segment is projected to be the fastest growing during the forecast period. This growth is driven by increasing internet penetration, rising consumer preference for convenience, and the availability of a wide range of products at competitive prices. In addition, the expansion of telehealth services and improvements in e-commerce platforms have enhanced the accessibility and reliability of online medication purchases. As digital healthcare adoption increases globally, the online channel is expected to witness substantial growth, especially in urban and tech-savvy regions.

Regional Analysis

Geographically, the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market has been segmented into North America, Europe, Asia-Pacific, Latin America, Middle East & Africa.

Major demand factors driving the North America market are the rising prevalence of osteoarthritis and joint disorders and growing aging population. The region also benefits from well-established healthcare infrastructure, widespread adoption of advanced medical treatments, and high awareness regarding non-surgical therapeutic options such as intra-articular injections. Additionally, increased healthcare spending and favorable reimbursement policies contribute to market growth in the region. However, the Asia-Pacific region is projected to be the fastest-growing during the forecast period. This growth is driven by a rapidly aging population, rising healthcare expenditure, growing awareness of joint health treatments, and expanding access to healthcare services across emerging economies such as China, India, and Southeast Asian countries.

Key Findings of the Study

• The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market is expected to reach USD 6.32 billion by 2035, at a CAGR of 6.15% during the forecast period.


• The North America region accounted for the fastest-growing global market.


• Based on the Product Type, the Hyaluronic Acid Injection segment was attributed to holding the largest market in 2024.


• Seikagaku Corporation, Bioventus, Inc., Anika Therapeutics, Inc., Zimmer Biomet, Sanofi, Teva Pharmaceutical Industries Ltd., Ferring B.V., Dr. Reddy's Laboratories Ltd., Fidia Farmaceutici S.p.A., Semical Biosurgery, Avanos Medical, Inc., Maxigen Biotech Inc. (MBI)are some of the players in the market.