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US Pharmacy Market

ID: MRFR/MED/14131-HCR
100 Pages
Garvit Vyas
October 2025

US Pharmacy Market Research Report By Product Type (Prescription Drugs, Over-The-Counter Drugs, Vaccines, Homeopathic Medicine), By Distribution Channel (Retail Pharmacy, Hospital Pharmacy, Online Pharmacy, Specialty Pharmacy), By Therapeutic Area (Cardiovascular, Oncology, Diabetes, Neurology, Infectious Diseases) and By Formulation (Tablets, Injectables, Topicals, Liquids) - Forecast to 2035

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US Pharmacy Market Infographic
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US Pharmacy Market Summary

As per MRFR analysis, the US pharmacy market Size was estimated at 233.33 USD Billion in 2024. The US pharmacy market is projected to grow from 246.02 USD Billion in 2025 to 417.9 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.44% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US pharmacy market is experiencing transformative growth driven by technological advancements and evolving healthcare needs.

  • Telepharmacy is gaining traction as a convenient option for patients, enhancing access to pharmaceutical care.
  • Personalized medicine is emerging as a key focus, tailoring treatments to individual patient profiles for improved outcomes.
  • Value-based care initiatives are reshaping reimbursement models, emphasizing quality over quantity in pharmacy services.
  • Technological advancements in pharmacy services and an aging population are significant drivers of market growth.

Market Size & Forecast

2024 Market Size 233.33 (USD Billion)
2035 Market Size 417.9 (USD Billion)

Major Players

CVS Health (US), Walgreens Boots Alliance (US), UnitedHealth Group (US), Cigna (US), Rite Aid (US), McKesson (US), Cardinal Health (US), AmerisourceBergen (US)

US Pharmacy Market Trends

The pharmacy market in the United States is currently experiencing a dynamic transformation, driven by various factors including technological advancements, regulatory changes, and evolving consumer preferences. The integration of digital health solutions, such as telepharmacy and mobile health applications, appears to be reshaping how patients access medications and healthcare services. This shift not only enhances convenience but also promotes better medication adherence and patient engagement. Furthermore, the increasing emphasis on personalized medicine and pharmacogenomics suggests a potential for tailored therapies that align with individual patient profiles, thereby improving treatment outcomes. In addition to technological innovations, the pharmacy market is witnessing a growing trend towards value-based care. This approach focuses on patient outcomes rather than the volume of services provided, which may lead to more efficient use of resources and improved healthcare quality. As pharmacies adapt to these changes, they are likely to play a crucial role in the broader healthcare ecosystem, collaborating with other healthcare providers to deliver comprehensive care. Overall, the current landscape indicates a shift towards a more integrated and patient-centered approach in the pharmacy market, which could redefine the future of medication management and healthcare delivery.

Rise of Telepharmacy

Telepharmacy is gaining traction as a viable option for patients seeking convenient access to pharmaceutical care. This trend allows pharmacists to provide consultations and medication management remotely, thereby expanding their reach and improving patient access to essential services.

Personalized Medicine

The focus on personalized medicine is becoming increasingly prominent within the pharmacy market. Tailored therapies based on genetic profiles may enhance treatment efficacy and minimize adverse effects, aligning with the growing demand for individualized healthcare solutions.

Value-Based Care Initiatives

The shift towards value-based care is influencing pharmacy practices, as providers aim to improve patient outcomes while managing costs. This approach encourages pharmacies to engage in collaborative care models, emphasizing the importance of patient health over service volume.

US Pharmacy Market Drivers

Shift Towards Preventive Healthcare

The growing emphasis on preventive healthcare is reshaping the pharmacy market landscape. As consumers become more health-conscious, there is an increasing demand for preventive services such as immunizations, health screenings, and wellness programs. Pharmacies are uniquely positioned to offer these services, making them integral to community health initiatives. In 2025, it is anticipated that pharmacies will administer over 50 million vaccinations annually, reflecting a shift towards proactive health management. This trend not only enhances the pharmacy's role in public health but also drives revenue growth through service diversification. By aligning with preventive healthcare strategies, pharmacies can strengthen their market presence and foster long-term relationships with patients.

Expansion of Pharmacy Benefit Managers (PBMs)

The role of Pharmacy Benefit Managers (PBMs) is increasingly pivotal in the pharmacy market, influencing drug pricing and access to medications. PBMs negotiate with drug manufacturers and pharmacies to manage prescription drug benefits for health plans. As the healthcare landscape evolves, the influence of PBMs is expected to grow, potentially impacting pharmacy revenues and patient access to medications. In 2025, it is projected that PBMs will manage over 80% of all prescription drug claims in the US. This consolidation may lead to increased competition among pharmacies, prompting them to enhance service offerings and patient engagement strategies. The dynamics introduced by PBMs could reshape the competitive landscape of the pharmacy market, necessitating adaptive strategies from pharmacies to thrive.

Regulatory Changes and Compliance Requirements

The pharmacy market is influenced by ongoing regulatory changes and compliance requirements that shape operational practices. In recent years, the US government has implemented stricter regulations regarding drug pricing, safety, and distribution. These changes compel pharmacies to adapt their business models to remain compliant while ensuring patient safety. For instance, the Drug Enforcement Administration (DEA) has increased scrutiny on controlled substances, necessitating enhanced tracking and reporting systems. As pharmacies invest in compliance measures, operational costs may rise, but this also presents opportunities for growth in specialized pharmacy services. The ability to navigate these regulatory landscapes effectively could position pharmacies as trusted healthcare providers, thereby enhancing their role in the pharmacy market.

Aging Population and Chronic Disease Management

The demographic shift towards an aging population in the US is significantly impacting the pharmacy market. By 2025, it is projected that approximately 20% of the US population will be aged 65 and older, leading to a higher prevalence of chronic diseases such as diabetes and hypertension. This demographic trend necessitates increased pharmaceutical care and medication management services. Pharmacies are likely to play a crucial role in managing these chronic conditions, providing medication therapy management and counseling services. Consequently, the demand for pharmacy services is expected to rise, potentially increasing the market size by 15% over the next five years. This driver underscores the importance of pharmacies in the healthcare continuum, particularly in supporting the health needs of an aging population.

Technological Advancements in Pharmacy Services

The pharmacy market is experiencing a notable transformation due to rapid technological advancements. Innovations such as automated dispensing systems and electronic health records are enhancing operational efficiency and patient safety. In 2025, it is estimated that over 60% of pharmacies in the US will adopt advanced technologies to streamline their services. This shift not only improves medication management but also facilitates better communication between pharmacists and healthcare providers. As a result, the pharmacy market is likely to see increased customer satisfaction and loyalty, driving growth in the sector. Furthermore, the integration of artificial intelligence in pharmacy operations may lead to more personalized patient care, thereby expanding the market's reach and potential revenue streams.

Market Segment Insights

By Product Type: Prescription Drugs (Largest) vs. Vaccines (Fastest-Growing)

In the US pharmacy market, the distribution among product types shows that Prescription Drugs hold the largest market share, driven by their essential role in treating chronic and acute conditions. Over-The-Counter Drugs follow as a significant category, catering to self-medication needs, while Vaccines and Homeopathic Medicine represent smaller yet crucial segments, with Vaccines gaining attention for their public health importance. Growth trends indicate that the segment is evolving, with Vaccines emerging as the fastest-growing category due to increased awareness of preventative healthcare. The rising prevalence of diseases requiring both preventative and therapeutic approaches is propelling the demand for Prescription Drugs, while consumer preference for Over-The-Counter options is also on the rise, influenced by convenience and accessibility.

Prescription Drugs: Dominant vs. Vaccines: Emerging

Prescription Drugs remain the dominant force in the US pharmacy market, characterized by a robust pipeline of new therapies and a strong emphasis on chronic disease management. The segment benefits from established relationships with healthcare providers and patients alike, driving consistent demand. In contrast, Vaccines are an emerging segment, spurred by rapid innovation and public health campaigns. This segment is experiencing significant growth due to heightened awareness of vaccination benefits, leading to increased uptake among various demographics. Both segments exhibit distinct characteristics, with Prescription Drugs focused on treatment efficacy, while Vaccines prioritize preventative care, showcasing their respective yet complementary roles in healthcare.

By Distribution Channel: Retail Pharmacy (Largest) vs. Online Pharmacy (Fastest-Growing)

In the US pharmacy market, the distribution channel segmentation reveals that Retail Pharmacy holds the largest market share, prominently serving as the primary source for medication and health products for consumers. Hospital Pharmacy also plays a significant role, providing medications primarily in hospital settings, while Specialty Pharmacy caters to patients with complex and chronic conditions, although it has a smaller share compared to retail counterparts. Online Pharmacy is capturing attention with its growing share, indicating a shift toward digital convenience in accessing pharmaceuticals. Growth trends within the distribution channels are notably dynamic, with Online Pharmacy emerging as the fastest-growing segment due to increasing consumer preference for home delivery and online purchasing options. The convenience offered by e-commerce platforms has significantly driven this segment's expansion. Retail Pharmacy remains dominant but faces challenges from online services and the growing demand for specialty medications, which require specialized handling and distribution, demonstrating a shift in consumer expectations and behavior towards convenience and personalized care.

Retail Pharmacy (Dominant) vs. Online Pharmacy (Emerging)

Retail Pharmacy is characterized by its extensive presence across urban and rural locations, providing consumers easy access to medications, over-the-counter products, and health consultations. This segment's dominance stems from its established infrastructure, customer trust, and comprehensive range of health services. On the other hand, Online Pharmacy represents an emerging paradigm, with its rapid growth fueled by technological advancements and changing consumer behaviors. It offers convenience, often lower prices, and a wider selection of products, appealing particularly to younger demographics who favor digital interactions. Both segments, while distinct in their approaches, reflect the evolving landscape of the pharmacy market, as they adapt to meet the changing needs of consumers in this dynamic environment.

By Therapeutic Area: Cardiovascular (Largest) vs. Oncology (Fastest-Growing)

The US pharmacy market reveals a complex landscape where cardiovascular medications capture the largest share, driven by the rising prevalence of heart diseases across various demographics. Following closely, oncology drugs are witnessing accelerated growth thanks to increasing cancer incidence and advancements in treatment options, which have heightened patient accessibility and awareness. Growth trends indicate that oncology is currently the fastest-growing segment, propelled by innovative therapies and a gradual shift towards personalized medicine. Additionally, the rising number of chronic health conditions, particularly obesity and diabetes, is leading to increased demand for related therapeutic areas. A robust pipeline of new drugs and ongoing research in biotechnology promise further expansions in both cardiovascular and oncology segments.

Cardiovascular (Dominant) vs. Diabetes (Emerging)

Cardiovascular treatments remain dominant in the US pharmacy market, representing a key focus for pharmaceutical companies due to the high demand for effective therapies. These drugs are crucial in managing various heart-related conditions, with established brands holding significant market share through continued trust and strong physician prescriptions. In contrast, the diabetes therapeutic area is emerging, driven by an escalating rate of diabetes cases linked to lifestyle factors. Innovative formulations, including GLP-1 agonists and SGLT2 inhibitors, are transforming diabetes management and capturing the attention of both healthcare providers and patients. As public health initiatives emphasize prevention and management, the diabetes segment is positioned for significant growth, attracting investment in research and development.

By Formulation: Tablets (Largest) vs. Injectables (Fastest-Growing)

In the US pharmacy market, the formulation segment is characterized by a diverse distribution among tablets, injectables, topicals, and liquids. Tablets continue to hold the largest market share due to their convenience and widespread acceptance among consumers. Meanwhile, injectables have garnered significant attention, emerging as the fastest-growing segment as the healthcare system shifts towards more innovative and effective treatment methods. The growth trends in this segment are heavily influenced by the increasing prevalence of chronic diseases and advancements in drug delivery systems. Tablets, being the traditional form of medication, maintain a steady demand. Conversely, the injectable segment is experiencing rapid expansion fueled by the rise in biologics and specialty drugs, prompting pharmacies to adapt and innovate to meet changing consumer and healthcare provider preferences.

Tablets: Dominant vs. Injectables: Emerging

Tablets are the dominant formulation type in the US pharmacy market, favored for their ease of use, accurate dosing, and cost-effectiveness. They cater to a wide range of conditions, making them a staple in pharmacies. On the other hand, injectables, while currently an emerging segment, are rapidly gaining ground due to advancements in delivery technologies and the increasing acceptance of biological therapies. They offer precise administration and faster therapeutic action, appealing to both healthcare providers and patients. This dynamic is reshaping the competitive landscape, with pharmacies exploring innovative approaches to accommodate the therapeutics of both dominant and emerging formulations.

Get more detailed insights about US Pharmacy Market

Key Players and Competitive Insights

The pharmacy market in the US is characterized by a competitive landscape that is increasingly shaped by digital transformation, strategic partnerships, and a focus on patient-centric services. Key players such as CVS Health (US), Walgreens Boots Alliance (US), and UnitedHealth Group (US) are actively redefining their operational strategies to enhance service delivery and improve customer engagement. CVS Health (US) has positioned itself as a leader in integrated healthcare services, emphasizing the expansion of its MinuteClinic offerings and telehealth services. Meanwhile, Walgreens Boots Alliance (US) is focusing on enhancing its digital capabilities and expanding its health and wellness services, which reflects a broader trend towards holistic healthcare solutions. UnitedHealth Group (US) continues to leverage its data analytics capabilities to optimize patient outcomes, indicating a shift towards more personalized healthcare solutions.

The business tactics employed by these companies include optimizing supply chains and localizing manufacturing to enhance efficiency and responsiveness to market demands. The competitive structure of the pharmacy market appears moderately fragmented, with several key players exerting significant influence. This fragmentation allows for a diverse range of services and products, fostering innovation and competition among the major players.

In October 2025, CVS Health (US) announced a strategic partnership with a leading telehealth provider to enhance its digital health offerings. This move is likely to strengthen CVS's position in the telehealth market, allowing it to provide more comprehensive healthcare solutions to its customers. The partnership underscores the growing importance of digital health services in the pharmacy sector, as consumers increasingly seek convenient and accessible healthcare options.

In September 2025, Walgreens Boots Alliance (US) launched a new initiative aimed at integrating artificial intelligence (AI) into its pharmacy operations. This initiative is expected to streamline prescription management and improve customer service through personalized recommendations. The integration of AI reflects a broader trend within the industry towards leveraging technology to enhance operational efficiency and customer experience.

In August 2025, UnitedHealth Group (US) expanded its pharmacy benefit management services through the acquisition of a regional pharmacy chain. This acquisition is anticipated to enhance UnitedHealth's ability to manage drug costs and improve patient access to medications. The strategic move aligns with the company's focus on integrated healthcare solutions and positions it to better compete in the evolving pharmacy landscape.

As of November 2025, the competitive trends within the pharmacy market are increasingly defined by digitalization, sustainability, and the integration of advanced technologies such as AI. Strategic alliances are playing a crucial role in shaping the current landscape, enabling companies to enhance their service offerings and operational capabilities. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition towards a focus on innovation, technology integration, and supply chain reliability, as companies strive to meet the changing needs of consumers.

Key Companies in the US Pharmacy Market market include

Industry Developments

Recent developments in the US Pharmacy Market have seen significant activity, including advancements in telehealth and increasing partnerships among major players. Notably, in October 2023, Walmart announced a strategic partnership with Humana to enhance health services in their pharmacies, aiming to improve access for their customers. CVS Health has been expanding its digital health initiatives, aligning with the trend of merging traditional pharmacy services with advanced technology. In terms of mergers and acquisitions, AmerisourceBergen, in September 2023, announced the acquisition of a key distribution firm that consolidates its supply chain efficiency. 

Walgreens Boots Alliance has also been focusing on reducing operational costs while enhancing its pharmacy services through various collaborations. The market valuation of companies like UnitedHealth Group and Cigna has shown substantial growth as they innovate their service offerings in line with evolving consumer demands and regulatory changes. McKesson, Cardinal Health, and others continue to navigate this dynamic environment, striving to optimize their logistical capabilities and improve patient care. Over the last few years, the integration of e-commerce through platforms like Amazon Pharmacy has disrupted traditional paradigms, contributing to a more competitive landscape within the US Pharmacy Market.

Future Outlook

US Pharmacy Market Future Outlook

The pharmacy market is projected to grow at a 5.44% CAGR from 2024 to 2035, driven by technological advancements, increasing healthcare demands, and evolving consumer preferences.

New opportunities lie in:

  • Expansion of telepharmacy services to enhance patient access and convenience.
  • Development of personalized medication management systems for chronic disease patients.
  • Implementation of AI-driven inventory management solutions to optimize supply chain efficiency.

By 2035, the pharmacy market is expected to achieve robust growth, positioning itself as a key player in healthcare.

Market Segmentation

US Pharmacy Market Formulation Outlook

  • Tablets
  • Injectables
  • Topicals
  • Liquids

US Pharmacy Market Product Type Outlook

  • Prescription Drugs
  • Over-The-Counter Drugs
  • Vaccines
  • Homeopathic Medicine

US Pharmacy Market Therapeutic Area Outlook

  • Cardiovascular
  • Oncology
  • Diabetes
  • Neurology
  • Infectious Diseases

US Pharmacy Market Distribution Channel Outlook

  • Retail Pharmacy
  • Hospital Pharmacy
  • Online Pharmacy
  • Specialty Pharmacy

Report Scope

MARKET SIZE 2024 233.33(USD Billion)
MARKET SIZE 2025 246.02(USD Billion)
MARKET SIZE 2035 417.9(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR) 5.44% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Billion
Key Companies Profiled CVS Health (US), Walgreens Boots Alliance (US), UnitedHealth Group (US), Cigna (US), Rite Aid (US), McKesson (US), Cardinal Health (US), AmerisourceBergen (US)
Segments Covered Product Type, Distribution Channel, Therapeutic Area, Formulation
Key Market Opportunities Integration of telepharmacy services to enhance patient access and medication management.
Key Market Dynamics Rising consumer demand for personalized medicine drives innovation and competition in the pharmacy market.
Countries Covered US

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FAQs

What is the projected market size of the US Pharmacy Market by 2035?

The US Pharmacy Market is expected to be valued at 186.38 USD billion by 2035.

What is the expected CAGR for the US Pharmacy Market from 2025 to 2035?

The expected CAGR for the US Pharmacy Market from 2025 to 2035 is 2.265 %.

Which product type is expected to hold the largest market share in 2035?

Prescription Drugs are expected to hold the largest market share, valued at 100.0 USD billion in 2035.

What is the market value for Over-The-Counter Drugs in 2024?

The market value for Over-The-Counter Drugs is expected to be 35.0 USD billion in 2024.

Who are the key players in the US Pharmacy Market?

Key players include AmerisourceBergen, CVS Health, and Walgreens Boots Alliance, among others.

What will the market value for Vaccines be in 2035?

The market value for Vaccines is projected to reach 30.0 USD billion by 2035.

What is the expected market value for Homeopathic Medicine in 2024?

Homeopathic Medicine is expected to have a market value of 10.68 USD billion in 2024.

How much is the market for Prescription Drugs expected to grow between 2024 and 2035?

The market for Prescription Drugs is expected to grow from 80.0 USD Billion in 2024 to 100.0 USD billion in 2035.

What challenges does the US Pharmacy Market face as it grows?

Challenges include regulatory changes and increasing competition among key players.

How is the overall US Pharmacy Market expected to change from 2024 to 2035?

The overall US Pharmacy Market is expected to increase from 145.68 USD Billion in 2024 to 186.38 USD Billion in 2035.

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