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    US Neurodegenerative Disease Market

    ID: MRFR/LS/51020-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    US Neurodegenerative Disease Market Research Report By Disease Type (Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Huntington's Disease), By Diagnosis Method (Neurological Examination, Imaging Techniques, Cerebrospinal Fluid Analysis, Electrophysiological Tests), By Treatment Type (Medication, Therapy, Rehabilitation, Surgical Interventions) and By Route of Administration (Oral, Injectable, Intravenous, Transdermal)-Forecast to 2035

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    US Neurodegenerative Disease Market Infographic
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    US Neurodegenerative Disease Market Summary

    The US Neurodegenerative Disease market is projected to grow significantly from 4.8 USD Billion in 2024 to 9 USD Billion by 2035.

    Key Market Trends & Highlights

    US Neurodegenerative Disease Key Trends and Highlights

    • The market is expected to expand at a compound annual growth rate of 5.88 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 9 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 4.8 USD Billion, reflecting the current demand for neurodegenerative disease treatments.
    • Growing adoption of innovative therapies due to increasing prevalence of neurodegenerative diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 4.8 (USD Billion)
    2035 Market Size 9 (USD Billion)
    CAGR (2025-2035) 5.88%

    Major Players

    Vertex Pharmaceuticals, Acadia Pharmaceuticals, Sarepta Therapeutics, AbbVie, Acorda Therapeutics, Teva Pharmaceutical Industries, GlaxoSmithKline, Takeda Pharmaceutical, UCB, Novartis, Roche, Biogen, Eli Lilly, Amgen

    US Neurodegenerative Disease Market Trends

    The US Neurodegenerative Disease Market is currently influenced by several vital trends. One prominent trend is the increasing investment in research and development of novel therapies, particularly for conditions such as Alzheimer's and Parkinson's diseases. This investment is largely driven by the aging population in the US, as the prevalence of neurodegenerative diseases rises with age. In addition, advancements in biotechnology are propelling the discovery of new drugs and treatment modalities, further shaping the market landscape. Key market drivers include heightened awareness and education regarding neurodegenerative diseases among healthcare providers and the general public.

    This increased understanding is leading to earlier diagnosis and intervention, which is essential for improving patient outcomes. Additionally, government initiatives supporting research funding and partnerships between public institutions and private companies facilitate progress in treatment options. The establishment of special task forces and funding programs by the National Institutes of Health (NIH) also plays a crucial role in advancing research efforts. Moreover, opportunities exist for the development of personalized medicine approaches in the US. Tailoring treatments to individual genetic profiles may vastly improve efficacy and patient satisfaction.

    The surge of digital health technologies, such as telemedicine and mobile health applications, is also paving the way for better disease management strategies, allowing patients to monitor their symptoms and treatment adherence more conveniently.  Recent trends show a shift toward collaboration between various stakeholders, including academia, pharmaceutical companies, and patient advocacy groups. This cooperative approach not only enhances research efforts but also ensures that the voices of patients are considered in the development of new therapies. Overall, the US Neurodegenerative Disease Market is evolving, with an emphasis on innovation and improved patient care.

    Source: Primary Research, Secondary Research, MRFR Database and Analyst Review

    Market Segment Insights

    US Neurodegenerative Disease Market Segment Insights

    US Neurodegenerative Disease Market Segment Insights

    Neurodegenerative Disease Market Disease Type Insights

    Neurodegenerative Disease Market Disease Type Insights  

    The US Neurodegenerative Disease Market, specifically focusing on the Disease Type segment, encompasses a range of complex and debilitating conditions that are primarily characterized by progressive degeneration of the nervous system. Among these, Alzheimer's Disease is particularly significant, being the most common form of dementia, impacting millions of individuals and demanding extensive healthcare resources for both treatment and caregiving. Following closely is Parkinson's Disease, which affects movement and motor skills, and poses unique challenges both for patients and caregivers, often leading to a need for long-term therapy and advanced care strategies.

    Additionally, Multiple Sclerosis represents a category that primarily affects young adults, often leading to a significant impact on the workforce and general quality of life, necessitating peer support and rehabilitation services. Amyotrophic Lateral Sclerosis, known for its aggressive progression, has drawn attention due to its severe loss of motor function, which not only affects patients but also strains the families and communities involved in their care. Huntington's Disease, which has genetic origins, creates a critical dialogue regarding genetic counseling and the future outlook for families at risk, emphasizing the importance of ongoing research and clinical studies.

    The US Neurodegenerative Disease Market segmentation reflects a growing acknowledgment of not just the medical needs but also the socio-economic implications of these diseases. With an increasing elderly population in the US, the burden of these neurodegenerative diseases is expected to rise, driving innovation, therapeutic advancements, and comprehensive care strategies tailored to each condition. Moreover, each disease type comes with its own set of healthcare challenges and treatment landscapes, which could be influenced by factors such as trends in home healthcare, advanced diagnostics, and lifestyle modifications that aim to mitigate risk factors.

    As public awareness increases and advocacy groups push for more research funding, the landscape for these diseases is evolving, presenting both significant opportunities for industry growth and challenges in meeting diverse patient needs. The US Neurodegenerative Disease Market continues to adapt to these shifts, highlighting the critical role of early diagnosis, personalized medicine, and holistic support systems that encompass not only physical health but also mental and emotional well-being for patients and their families.

    Neurodegenerative Disease Market Diagnosis Method Insights  

    Neurodegenerative Disease Market Diagnosis Method Insights  

    The Diagnosis Method segment of the US Neurodegenerative Disease Market plays a crucial role in identifying and differentiating various neurodegenerative disorders. This segment encompasses several techniques, including Neurological Examination, Imaging Techniques, Cerebrospinal Fluid Analysis, and Electrophysiological Tests. Neurological Examinations are fundamental, enabling clinicians to assess patients through cognitive and physical tests, which aid in early detection and management. Imaging Techniques, such as MRI and PET scans, are vital for visualizing brain structure and function, facilitating accurate diagnosis by revealing abnormalities typical of conditions like Alzheimer's and Parkinson's diseases.

    Cerebrospinal Fluid Analysis provides critical information from the fluid surrounding the brain and spinal cord, highlighting biomarkers associated with neurodegeneration. Electrophysiological Tests assess the electrical activity of the brain and nerves, offering insights into functional impairments. Together, these diagnostic methods enhance our understanding, offering healthcare professionals the tools necessary for a precise diagnosis, which is essential for developing effective treatment plans in the growing field of neurodegenerative disease management. As the demand for effective diagnostics rises, these methodologies are becoming increasingly significant within the US Neurodegenerative Disease Market.

    Neurodegenerative Disease Market Treatment Type Insights  

    The Treatment Type segment of the US Neurodegenerative Disease Market encompasses various approaches to managing neurodegenerative conditions, including Medication, Therapy, Rehabilitation, and Surgical Interventions. Medication plays a critical role, focusing on the use of pharmacological therapies to slow disease progression and alleviate symptoms, thereby offering significant benefits to patients. Therapy, which includes cognitive and physical therapies, is vital for enhancing the quality of life and helping patients retain functional abilities. Rehabilitation is also a key component, aimed at restoring independence and functionality to individuals experiencing motor and cognitive impairments resulting from neurodegenerative diseases.

    Surgical Interventions, though less common, can be pivotal in specific cases, offering potential solutions for patients with advanced stages of disease. This segment is influenced by the increasing prevalence of neurodegenerative diseases in the US, driven by an aging population and changes in lifestyle. The ongoing Research and Development efforts are poised to introduce innovative treatment modalities, creating new opportunities for improved patient outcomes and market evolution. As this segment progresses, it will be essential to address challenges such as treatment accessibility, affordability, and the need for personalized approaches tailored to individual patient needs.

    Neurodegenerative Disease Market Route of Administration Insights  

    Neurodegenerative Disease Market Route of Administration Insights  

    The Route of Administration segment is a crucial aspect of the US Neurodegenerative Disease Market, encompassing various methods such as Oral, Injectable, Intravenous, and Transdermal. Each of these methods showcases unique advantages that facilitate patient compliance and treatment efficacy. Oral administration remains a popular choice due to its ease of use and convenience for patients, significantly impacting medication adherence rates. Injectable methods provide rapid therapeutic action, essential for conditions requiring immediate relief, while Intravenous administration is particularly beneficial in clinical settings, allowing for direct and swift delivery of medication.

    Transdermal delivery systems offer the advantage of prolonged release and steady drug levels, contributing to improved convenience for chronic patients. The growing prevalence of neurodegenerative diseases, along with advancements in pharmaceutical formulations, is further driving the development and adoption of diverse routes of administration in the US market. This segment is vital for overall treatment strategies, enhancing patient experience and outcomes in managing these complex conditions. With continuous research and development, the evolution of administration methods is expected to provide innovative solutions that align with the rising patient population and their unique needs.

    Get more detailed insights about US Neurodegenerative Disease Market

    Key Players and Competitive Insights

    The US Neurodegenerative Disease Market is characterized by a diverse landscape of innovative companies working to address various conditions such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis. With an increasing prevalence of these disorders and a growing elderly population, the market is witnessing significant investment in research and development aimed at discovering novel therapeutic solutions. The competitive dynamics are shaped by a mix of established pharmaceutical companies and emerging biotech firms, all vying for market share and striving to bring groundbreaking treatments to patients.

    Evolving technologies, regulatory changes, and shifting patient needs continue to influence the direction of the industry, making it imperative for companies to adapt and innovate. Vertex Pharmaceuticals holds a notable position within the US Neurodegenerative Disease Market, leveraging its research expertise and strong clinical development capabilities to create impactful therapies. The company is recognized for its focus on developing treatments tailored to specific patient populations, which enhances its appeal among healthcare providers and patients alike. Vertex's commitment to addressing unmet needs in neurodegenerative disorders is reflected in its robust pipeline and strategic collaborations aimed at accelerating drug development.

    The company benefits from a solid financial foundation and a reputation for scientific excellence that enhances its competitive edge, enabling it to efficiently navigate the complexities of the neurodegenerative disease landscape. Acadia Pharmaceuticals is also a key player in the US Neurodegenerative Disease Market, with a clear focus on central nervous system disorders. Known for its flagship product targeting Parkinson's disease, Acadia has built a strong presence within the market by offering innovative therapies that improve treatment outcomes for patients.

    The company's dedication to advancing the care for neurodegenerative diseases is underscored by its commitment to research and development, reflecting the strengths of a dedicated clinical team. Strategic partnerships and acquisitions have played a crucial role in expanding Acadia's product offerings and enhancing its research capabilities. This proactive approach not only strengthens Acadia's market presence but also positions the company as a formidable competitor in the evolving landscape of neurodegenerative disease treatment in the US.

    Key Companies in the US Neurodegenerative Disease Market market include

    Industry Developments

    In recent developments within the US Neurodegenerative Disease Market, a notable focus has been on Vertex Pharmaceuticals and Acadia Pharmaceuticals, which are advancing their pipelines for treatments related to various neurodegenerative conditions. In October 2023, AbbVie announced positive results from a phase 3 study for its Alzheimer’s drug, indicating progress in addressing cognitive decline. Furthermore, Biogen and Eli Lilly are engaged in collaborative Research and Development efforts aimed at innovative therapies for Alzheimer’s and related disorders, showcasing the trend of strategic partnerships in the industry.

    Recent acquisitions include Amgen's strategic purchase of a biotech firm in August 2023, aiming to enhance its capabilities in neurodegenerative disease therapies. Acorda Therapeutics continues to experience growth attributed to its market strategies and product offerings, reflecting a broader trend of increasing market valuation across the sector, which is projected to expand significantly in the coming years. The ongoing investments and mergers signal a robust activity in tackling neurodegenerative diseases, with significant implications for patients and healthcare providers in the US. Major market players such as Roche and Novartis maintain competitive momentum through innovative clinical trials and product launches.

    Market Segmentation

    Neurodegenerative Disease Market Disease Type Outlook

    • Alzheimer's Disease

    Neurodegenerative Disease Market Treatment Type Outlook

    • Medication

    Neurodegenerative Disease Market Diagnosis Method Outlook

    • Neurological Examination

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 4.25(USD Billion)
    Market Size 2024 4.8(USD Billion)
    Market Size 2035 9.0(USD Billion)
    Compound Annual Growth Rate (CAGR) 5.881% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Vertex Pharmaceuticals, Acadia Pharmaceuticals, Sarepta Therapeutics, AbbVie, Acorda Therapeutics, Teva Pharmaceutical Industries, GlaxoSmithKline, Takeda Pharmaceutical, UCB, Novartis, Roche, Biogen, Eli Lilly, Amgen
    Segments Covered Disease Type, Diagnosis Method, Treatment Type, Route of Administration
    Key Market Opportunities Innovative therapeutics development, Early diagnostic tools advancement, Telemedicine integration for care, Biomarker discovery and validation, Patient-centered care models expansion
    Key Market Dynamics Aging population increase, Rising healthcare costs, Advances in drug development, Growing patient awareness, Increased funding for research
    Countries Covered US

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    FAQs

    What is the expected market size of the US Neurodegenerative Disease Market in 2024?

    The expected market size of the US Neurodegenerative Disease Market in 2024 is valued at 4.8 USD Billion.

    What is the projected market size of the US Neurodegenerative Disease Market in 2035?

    The projected market size of the US Neurodegenerative Disease Market in 2035 is valued at 9.0 USD Billion.

    What is the expected compound annual growth rate (CAGR) for the US Neurodegenerative Disease Market from 2025 to 2035?

    The expected compound annual growth rate (CAGR) for the US Neurodegenerative Disease Market from 2025 to 2035 is 5.881%.

    Which disease type holds the largest market share within the US Neurodegenerative Disease Market?

    Alzheimer's Disease holds the largest market share within the US Neurodegenerative Disease Market, with a value of 1.5 USD Billion in 2024.

    What is the expected market size for Parkinson's Disease in 2035?

    The expected market size for Parkinson's Disease in 2035 is 1.9 USD Billion.

    Who are the major players in the US Neurodegenerative Disease Market?

    Major players in the US Neurodegenerative Disease Market include Vertex Pharmaceuticals, Acadia Pharmaceuticals, and Biogen among others.

    What will be the market size for Multiple Sclerosis in 2024?

    The market size for Multiple Sclerosis in 2024 is valued at 0.9 USD Billion.

    What is the expected market size for Amyotrophic Lateral Sclerosis by 2035?

    The expected market size for Amyotrophic Lateral Sclerosis by 2035 is 1.0 USD Billion.

    What are the key growth drivers influencing the US Neurodegenerative Disease Market?

    Key growth drivers include rising prevalence of neurodegenerative diseases and advancements in drug development.

    What is the expected market size for Huntington's Disease in 2024?

    The expected market size for Huntington's Disease in 2024 is valued at 0.9 USD Billion.

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