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UK Plasma Fractionation Market Research Report By Product Type (Immunoglobulin, Albumin, Coagulation Factors, Protease Inhibitors), By Application (Neurology, Hematology, General Medicine, Immunology), By End User (Hospitals, Ambulatory Surgical Centers, Blood Banks, Pharmaceutical Companies) and By Technology (Centrifugation, Chromatography, Precipitation, Filtration)-Forecast to 2035


ID: MRFR/HC/47612-HCR | 200 Pages | Author: Rahul Gotadki| May 2025

UK Plasma Fractionation Market Overview


As per MRFR analysis, the UK Plasma Fractionation Market Size was estimated at 1.02 (USD Billion) in 2024.The UK Plasma Fractionation Market Industry is expected to grow from 1.06(USD Billion) in 2025 to 1.6 (USD Billion) by 2035. The UK Plasma Fractionation Market CAGR (growth rate) is expected to be around 3.772% during the forecast period (2025 - 2035).


Key UK Plasma Fractionation Market Trends Highlighted


The UK Plasma Fractionation Market has been experiencing notable trends rooted in the increasing demand for immunoglobulin therapies and advancements in biotechnology. One key market driver is the rising prevalence of chronic diseases that require plasma-derived therapies, which has driven both public and private investments in plasma fractionation research and development. Furthermore, the UK government actively supports the sector through various initiatives and funding programs aimed at enhancing the capabilities of domestic plasma collection facilities, which provides a robust foundation for growth in the industry. Another significant opportunity lies in the expansion of personalized medicine, which necessitates more specialized plasma-derived products.

Companies in the UK can explore collaborations with research institutions and healthcare providers to create tailored therapies. The increasing focus on hemophilia and autoimmune diseases has fueled innovation in the types of treatments being developed, so addressing specific patient needs will be crucial. Recent trends indicate a strong push towards improving the efficiency of plasma collection and processing. The adoption of advanced technologies such as automation and artificial intelligence is becoming more common, which helps to streamline operations and reduce costs.

Additionally, there has been a societal shift toward supporting ethical sourcing and sustainable practices within the healthcare industry.As a result, there is a growing emphasis on ensuring that plasma donation processes adhere to stringent safety standards while also promoting donor awareness programs to encourage participation. Overall, the convergence of these factors drives the UK Plasma Fractionation Market, helping to shape its future trajectory.


UK Plasma Fractionation Market size


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


UK Plasma Fractionation Market Drivers


Increasing Prevalence of Hematological Disorders


The increasing prevalence of hematological disorders such as hemophilia and thrombocytopenia in the UK is a significant driver for the UK Plasma Fractionation Market Industry. According to recent data from NHS Blood and Transplant, around 30,000 people in the UK are affected by hemophilia and related bleeding disorders. This has led to a heightened demand for immunoglobulins and clotting factors derived from plasma fractionation. Additionally, the increasing awareness of treatment options and constant advancements in the therapeutic use of plasma proteins encourage healthcare providers to utilize plasma-derived therapeutics, further expanding the UK Plasma Fractionation Market.


Advancements in Research and Development


Research and Development (R&D) activities are propelling the UK Plasma Fractionation Market Industry forward. It is reported that the UK invests around 4.5 billion annually in biomedical research, leading to innovative plasma fractionation methods and improved product efficacy. Organizations like the Medical Research Council and the Biotechnology and Biological Sciences Research Council are at the forefront of funding and supporting breakthroughs in plasma therapies.Advances in technology have paved the way for the better extraction of immunoglobulins and clotting factors, thus positively impacting the market growth and product offerings.


Supportive Regulatory Environment


The supportive regulatory environment in the UK plays a crucial role in fostering the growth of the Plasma Fractionation Market Industry. The UK Medicines and Healthcare Regulatory Agency (MHRA) lays down stringent guidelines for the quality and safety of blood products, encouraging manufacturers to comply with high standards. This commitment to safety reassures patients and healthcare providers about the therapeutic benefits of plasma-derived products.The MHRA’s Therapy Approval fast-tracking projects can bring innovations to the market faster and open up more possibilities for major advancements in the sector.


Growing Demand for Immunoglobulin Therapy


The growing demand for immunoglobulin therapy in the UK is a major contributor to the expanding UK Plasma Fractionation Market Industry. Recent reports indicate that the consumption of immunoglobulin therapy has risen by approximately 9% annually, influenced by the increased incidence of autoimmune disorders and infections. The UK Government acknowledges the importance of immunoglobulin in treating various conditions, leading to increased funding for its procurement.Organizations such as the National Health Service (NHS) are focusing on ensuring a steady supply of immunoglobulins, reflecting a commitment to patient care and further driving market dynamics.


UK Plasma Fractionation Market Segment Insights


Plasma Fractionation Market Product Type Insights


The UK Plasma Fractionation Market exhibits an intricate segmentation based on Product Type, with several categories demonstrating their unique contributions to the overall industry dynamics. Immunoglobulin has emerged as a significant player within this market, extensively utilized for treating various immunodeficiency disorders and autoimmune diseases, thereby reflecting its widespread importance in healthcare settings across the UK. Albumin, a vital protein derived from plasma, plays a critical role in maintaining oncotic pressure and is extensively used in therapeutic applications, particularly in critical care, underlining its essential function in patient management.

Additionally, Coagulation Factors are indispensable in the treatment of hemophilia and other bleeding disorders, highlighting their crucial impact on clinical practices and patient outcomes. Protease Inhibitors represent another pivotal element, largely contributing to the management of various viral infections and inflammatory conditions, showcasing their relevance in both therapeutic and research settings. The UK Plasma Fractionation Market segmentation illustrates how these particular product types cater to diverse therapeutic needs and contribute to improved patient outcomes, reflecting a landscape where innovation and demand for effective treatment modalities continue to grow.

The increasing prevalence of chronic diseases and the rising geriatric population in the UK further bolster the demand for these products, propelling advancements in research and technological applications within the market. As the industry evolves, opportunities for enhanced product offerings and competitive strategies are anticipated as stakeholders seek to address pressing health challenges through advanced plasma-derived therapies.


UK Plasma Fractionation Market Segment


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Plasma Fractionation Market Application Insights


The UK Plasma Fractionation Market has seen significant engagement in the Application segment, which comprises various fields including Neurology, Hematology, General Medicine, and Immunology. In Neurology, the use of plasma-derived products is critical for conditions like multiple sclerosis, where therapies derived from plasma offer relief to patients. Hematology is another crucial field, as plasma components play a vital role in addressing blood disorders and managing transfusions. General Medicine benefits from a broad spectrum of plasma-derived therapies, enhancing patient care across multiple conditions.Immunology stands out for its focus on developing immunoglobulins that provide critical support against immune deficiencies.

Collectively, these applications enhance patient outcomes and cater to the increasing demand for effective treatments in the UK healthcare system, aligning with ongoing advancements in therapeutic strategies and technologies. The overall growth in these applications reflects the rising awareness and investment in the UK Plasma Fractionation Market, driven by healthcare innovations and the need for improved medical solutions.As the industry strengthens, collaboration among researchers and practitioners is likely to flourish, ensuring continued progress in plasma-derived therapies.


Plasma Fractionation Market End User Insights


The End User segment of the UK Plasma Fractionation Market encompasses critical areas including Hospitals, Ambulatory Surgical Centers, Blood Banks, and Pharmaceutical Companies, all of which play a significant role in healthcare delivery. Hospitals hold a majority share as they rely heavily on plasma-derived therapies for treating a variety of health conditions, including immune deficiencies and hemophilia. Ambulatory Surgical Centers are increasingly utilizing plasma products to provide specialized care in outpatient settings, thereby enhancing patient accessibility and convenience.Blood Banks are fundamental in the collection and processing of plasma, contributing to the availability of life-saving therapies and products.

Pharmaceutical Companies are actively involved in the research and development of new plasma-based medications, aiming to expand treatment options and improve patient outcomes. The growth of the End User segment is bolstered by trends such as the rising incidence of chronic diseases and advancements in medical technology. Furthermore, regulatory support and increased funding for plasma research are expected to create additional opportunities within the sector, enabling the UK to remain a key player in global plasma fractionation markets.


Plasma Fractionation Market Technology Insights


The UK Plasma Fractionation Market within the Technology segment exhibits a steady growth trajectory driven by increasing demands for blood and plasma-derived products. Centrifugation plays a critical role, as it effectively separates plasma components, making it a foundational technology in this market. Chromatography is significant due to its precision in purifying proteins, which is vital for therapeutic applications and research endeavors. Precipitation methods contribute to the efficiency of isolating specific plasma proteins, addressing the increasing need for targeted therapies.Filtration technologies are important for ensuring product safety and purity, which aligns with stringent regulatory requirements in the UK.

Collectively, these technologies not only enhance the quality and efficacy of plasma products but also align with the growing emphasis on innovative healthcare solutions in the UK. As the market evolves, advancements in these technologies present significant opportunities for efficiency improvements, cost reductions, and enhanced product development, all contributing positively to the dynamics of the UK Plasma Fractionation Market.


UK Plasma Fractionation Market Key Players and Competitive Insights


The UK Plasma Fractionation Market is a competitive and dynamic industry that plays a crucial role in the healthcare sector by producing lifesaving therapies derived from human plasma. This market is characterized by a strong focus on innovation, regulatory compliance, and the need for high-quality products due to the critical nature of plasma-derived therapies in treating various medical conditions. Competitors in this market have been increasingly investing in research and development to enhance their product offerings and maintain a competitive edge. Additionally, collaborations and partnerships between industry players, academic institutions, and healthcare organizations have become more prevalent, emphasizing the importance of collective efforts toward advancing plasma-derived therapies and addressing patients' needs effectively.

The market is influenced by factors such as increasing demand for immunoglobulins and coagulants, advancements in fractionation technologies, and a growing focus on patient care, shaping the competitive landscape of the UK Plasma Fractionation sector.Octapharma has established a solid presence in the UK Plasma Fractionation Market, gaining recognition for its commitment to quality and innovation. The company focuses on providing high-quality human protein products, specifically immunoglobulins and albumin, which are vital for treating various clinical conditions. Octapharma’s strengths lie in its extensive research and development efforts, which have led to the introduction of novel therapies and improved production techniques.

The company operates state-of-the-art manufacturing facilities that adhere to strict regulatory standards, ensuring the safety and efficacy of its products. Its commitment to patient care and solid distribution channels have enabled Octapharma to build strong relationships with healthcare providers in the UK, securing a reputable position in the plasma market and contributing significantly to patient outcomes.Grifols is a leading player in the UK Plasma Fractionation Market, known for its comprehensive portfolio of plasma-derived medicines that address a wide range of health issues. The company's key products include immunoglobulins, albumin, and clotting factors used to treat conditions such as immune deficiencies and hemophilia.

Grifols has a robust market presence in the UK due to its innovative approach and strong dedication to quality. The company has strategically invested in expanding its manufacturing capabilities through mergers and acquisitions, enhancing its product offerings and production efficiency. This strategic growth not only strengthens Grifols' position in the market but also enables it to better serve the increasing demand for plasma-derived therapies. With a focus on research and development, Grifols continues to advance the science of plasma fractionation, positioning itself as a crucial contributor to the UK healthcare landscape while maintaining a strong emphasis on patient safety and quality assurance.


Key Companies in the UK Plasma Fractionation Market Include



  • Octapharma

  • Grifols

  • HemaCare

  • Takeda Pharmaceutical

  • Sangamo Therapeutics

  • Baxter International

  • CSL Behring

  • Thermo Fisher Scientific

  • Sangart

  • Fresenius Kabi

  • LFB

  • BioLife Plasma Services

  • ADMA Biologics

  • Kedrion Biopharma


UK Plasma Fractionation Market Industry Developments


The UK Plasma Fractionation Market has seen significant developments recently, particularly with the growing investments and expansions by major companies such as Octapharma, Grifols, and CSL Behring. In September 2023, Octapharma announced plans to expand its production capabilities in the UK, aligning with the increased demand for immunoglobulin therapy. Concurrently, Grifols revealed investments aimed at enhancing its research and development facilities within the region. In terms of mergers and acquisitions, Takeda Pharmaceutical confirmed its acquisition of a specialized plasma therapy company in August 2023 to bolster its portfolio, while Baxter International has been actively pursuing partnerships to optimize its plasma supply chain.


Recent growth estimates show a vibrant market valuation, with significant opportunities driven by the increasing prevalence of chronic diseases. Moreover, the UK health authorities have recognized the importance of plasma-derived therapies, reinforcing regulatory frameworks to support market expansion. Over the past few years, the market has been marked by technological advancements and rising awareness about the benefits of plasma-derived products, with a notable increase in blood donation campaigns initiated by organizations like NHS Blood and Transplant to secure a steady plasma supply.


UK Plasma Fractionation Market Segmentation Insights


Plasma Fractionation Market Product Type Outlook



  • Immunoglobulin

  • Albumin

  • Coagulation Factors

  • Protease Inhibitors


Plasma Fractionation Market Application Outlook



  • Neurology

  • Hematology

  • General Medicine

  • Immunology


Plasma Fractionation Market End User Outlook



  • Hospitals

  • Ambulatory Surgical Centers

  • Blood Banks

  • Pharmaceutical Companies


Plasma Fractionation Market Technology Outlook



  • Centrifugation

  • Chromatography

  • Precipitation

  • Filtration

Report Attribute/Metric Source: Details
MARKET SIZE 2023 1.02 (USD Billion)
MARKET SIZE 2024 1.06 (USD Billion)
MARKET SIZE 2035 1.6 (USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR) 3.772% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Billion
KEY COMPANIES PROFILED Octapharma, Grifols, HemaCare, Takeda Pharmaceutical, Sangamo Therapeutics, Baxter International, CSL Behring, Thermo Fisher Scientific, Sangart, Fresenius Kabi, LFB, BioLife Plasma Services, ADMA Biologics, Kedrion Biopharma
SEGMENTS COVERED Product Type, Application, End User, Technology
KEY MARKET OPPORTUNITIES Increasing demand for immunoglobulins, Expansion of chronic disease management, Growth in gene therapies, Rising investments in R&D, Enhanced focus on plasma collection efficiency
KEY MARKET DYNAMICS growing demand for immunoglobulins, increasing prevalence of hemophilia, rising healthcare expenditure, technological advancements in processing, stringent regulatory frameworks
COUNTRIES COVERED UK


Frequently Asked Questions (FAQ) :

The UK Plasma Fractionation Market is expected to be valued at 1.06 USD Billion in 2024.

The UK Plasma Fractionation Market is projected to reach a value of 1.6 USD Billion by 2035.

The market is expected to grow at a CAGR of 3.772 percent from 2025 to 2035.

Immunoglobulin is expected to hold the largest market share within the UK Plasma Fractionation Market.

The market value of Immunoglobulin is expected to be 0.45 USD Billion in 2024.

Major players include Octapharma, Grifols, Takeda Pharmaceutical, and CSL Behring among others.

The expected market value for Albumin in 2035 is projected to be 0.4 USD Billion.

Key growth opportunities arise from increasing demand for immunoglobulins and albumin products.

The Coagulation Factors market is valued at 0.2 USD Billion in 2024.

The market size for Protease Inhibitors is expected to reach 0.25 USD Billion by 2035.

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