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South America Creutzfeldt Jakob Disease Market

ID: MRFR/HC/52727-HCR
200 Pages
Rahul Gotadki
October 2025

South America Creutzfeldt-Jakob Disease Market Research Report By Type (Sporadic Creutzfeldt-Jakob Disease, Familial Creutzfeldt-Jakob Disease, Iatrogenic Creutzfeldt-Jakob Disease, Variant Creutzfeldt-Jakob Disease), By Diagnosis Method (Electroencephalogram, Magnetic Resonance Imaging, Cerebrospinal Fluid Tests, Brain Biopsy), By Treatment Approach (Supportive Care, Experimental Therapies, Symptomatic Treatment), By End User (Hospitals, Diagnostic Laboratories, Research Institutes) and By Regional (Brazil, Mexico, Argentina, Rest of South... read more

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South America Creutzfeldt Jakob Disease Market Summary

As per MRFR analysis, the South America creutzfeldt jakob-disease market size was estimated at $40.0 Million in 2024. The South America creutzfeldt jakob-disease market is projected to grow from 42.35 $ Million in 2025 to 75.0 $ Million by 2035, exhibiting a compound annual growth rate (CAGR) of 5.88% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America creutzfeldt jakob-disease market is experiencing notable growth driven by increased awareness and advancements in research.

  • Brazil remains the largest market for creutzfeldt jakob disease, reflecting a robust healthcare infrastructure and research capabilities.
  • Mexico is emerging as the fastest-growing region, with heightened focus on neurodegenerative disorders and innovative treatment approaches.
  • There is a marked increase in collaboration among health agencies, fostering a more integrated response to the disease.
  • Key market drivers include the rising incidence of neurodegenerative disorders and advancements in diagnostic technologies, which are shaping the market landscape.

Market Size & Forecast

2024 Market Size 40.0 (USD Million)
2035 Market Size 75.0 (USD Million)

Major Players

Grifols (ES), Karyopharm Therapeutics (US), Prionics AG (CH), Bio-Rad Laboratories (US), Thermo Fisher Scientific (US), Fujirebio (JP), CureVac (DE), Sangamo Therapeutics (US)

South America Creutzfeldt Jakob Disease Market Trends

The creutzfeldt jakob-disease market in South America is characterized by a complex interplay of factors influencing diagnosis, treatment, and patient care. The region has witnessed a gradual increase in awareness regarding this rare neurodegenerative disorder, which is primarily caused by prion proteins. This heightened awareness has led to improved diagnostic capabilities, enabling healthcare professionals to identify cases more effectively. Furthermore, the healthcare infrastructure in several South American countries is evolving, with investments aimed at enhancing research and development in the field of prion diseases. This evolution may potentially lead to the introduction of novel therapeutic options in the future. Despite these advancements, challenges remain in the creutzfeldt jakob-disease market. Limited access to specialized care and treatment options continues to hinder patient outcomes. Additionally, the rarity of the disease complicates the allocation of resources for research and public health initiatives. Nevertheless, ongoing collaborations between governmental health agencies and research institutions may foster a more robust framework for addressing the needs of affected individuals. As the landscape of the creutzfeldt jakob-disease market continues to evolve, stakeholders must remain vigilant in their efforts to improve patient care and advance scientific understanding of this complex condition.

Increased Awareness and Education

There is a noticeable rise in awareness and education regarding creutzfeldt jakob disease among healthcare professionals and the general public in South America. This trend is likely driven by initiatives from health authorities aimed at disseminating information about the disease's symptoms, transmission, and management. Enhanced education may lead to earlier diagnosis and better patient outcomes.

Research and Development Initiatives

Research and development initiatives focused on prion diseases are gaining momentum in South America. Government funding and partnerships with academic institutions are fostering innovation in diagnostic tools and potential treatments. This trend suggests a commitment to addressing the challenges posed by creutzfeldt jakob disease and improving healthcare responses.

Collaboration Among Health Agencies

Collaboration among various health agencies is becoming increasingly important in the creutzfeldt jakob-disease market. Joint efforts between governmental bodies and non-governmental organizations are aimed at improving surveillance, data collection, and resource allocation. Such collaborations may enhance the overall understanding of the disease and facilitate better management strategies.

South America Creutzfeldt Jakob Disease Market Drivers

Government Initiatives and Funding

Government initiatives aimed at combating rare diseases are likely to play a pivotal role in shaping the creutzfeldt jakob-disease market in South America. Increased funding for research and public health campaigns can enhance awareness and understanding of prion diseases among healthcare professionals and the general public. For instance, several South American countries have begun to allocate specific budgets for rare disease research, which could lead to breakthroughs in treatment and management strategies. This financial support may also encourage collaboration between public and private sectors, fostering innovation within the creutzfeldt jakob-disease market. As a result, the overall landscape for treatment options and patient support services may improve significantly.

Advancements in Diagnostic Technologies

Technological advancements in diagnostic tools are poised to transform the creutzfeldt jakob-disease market in South America. Innovations such as improved imaging techniques and biomarker identification are enabling earlier and more accurate diagnosis of prion diseases. This is particularly crucial, as timely diagnosis can significantly impact treatment efficacy and patient management. The market for diagnostic devices is expected to grow, with estimates suggesting a compound annual growth rate (CAGR) of around 8% over the next five years. As healthcare providers increasingly adopt these advanced technologies, the demand for specialized diagnostic services in the creutzfeldt jakob-disease market is likely to surge, leading to enhanced patient care and potentially better health outcomes.

Growing Interest in Personalized Medicine

The trend towards personalized medicine is emerging as a crucial driver for the creutzfeldt jakob-disease market. Tailoring treatment approaches based on individual patient profiles could enhance therapeutic efficacy and minimize adverse effects. In South America, there is a growing recognition of the need for personalized treatment strategies for neurodegenerative diseases, including prion diseases. This shift may lead to increased investment in genetic research and biomarker discovery, which are essential for developing targeted therapies. As healthcare providers adopt more personalized approaches, the creutzfeldt jakob-disease market may witness a transformation in treatment paradigms, potentially improving patient outcomes and satisfaction.

Rising Incidence of Neurodegenerative Disorders

The increasing prevalence of neurodegenerative disorders in South America appears to be a significant driver for the creutzfeldt jakob-disease market. As the population ages, the incidence of such diseases is projected to rise, leading to heightened demand for diagnostic and therapeutic solutions. Recent studies indicate that the incidence of prion diseases, including creutzfeldt jakob disease, may be underreported, suggesting that the actual market potential could be larger than currently estimated. This trend is likely to stimulate investment in research and development, as healthcare providers seek to address the growing burden of these conditions. Furthermore, the healthcare system's response to this rising incidence may involve increased funding and resources allocated to the creutzfeldt jakob-disease market, thereby enhancing the availability of treatment options and improving patient outcomes.

Increased Collaboration Among Research Institutions

The landscape of the creutzfeldt jakob-disease market is likely to benefit from enhanced collaboration among research institutions in South America. Joint research initiatives can facilitate knowledge sharing and resource pooling, leading to accelerated advancements in understanding prion diseases. Collaborative efforts may also attract funding from both governmental and non-governmental organizations, further bolstering research capabilities. As institutions work together, they can conduct larger-scale studies that provide more robust data on disease prevalence and treatment efficacy. This collaborative environment is expected to foster innovation and drive the development of new therapies within the creutzfeldt jakob-disease market, ultimately benefiting patients and healthcare providers alike.

Market Segment Insights

By Type: Sporadic Creutzfeldt-Jakob Disease (Largest) vs. Variant Creutzfeldt-Jakob Disease (Fastest-Growing)

In the segment of Creutzfeldt-Jakob disease types, Sporadic Creutzfeldt-Jakob Disease (sCJD) holds the largest share, significantly dominating the market due to its widespread occurrence in South America. This type is characterized by its spontaneous onset and has consistently shown a higher prevalence compared to familial and iatrogenic cases. Variant Creutzfeldt-Jakob Disease (vCJD), while less common, has gained attention due to emerging cases linked to bovine spongiform encephalopathy (BSE) and is recognized as the fastest-growing segment in recent years. Growth trends within this segment are influenced by factors such as increasing awareness, improved diagnostic capabilities, and the ongoing surveillance of potential outbreaks. The rise in vCJD cases is particularly notable, leading to urgent research efforts and public health initiatives aimed at understanding and controlling transmission pathways. Additionally, advancements in genetic testing for familial cases have propelled growth in awareness, impacting overall market dynamics positively.

Sporadic Creutzfeldt-Jakob Disease (Dominant) vs. Variant Creutzfeldt-Jakob Disease (Emerging)

Sporadic Creutzfeldt-Jakob Disease is recognized as the dominant form of Creutzfeldt-Jakob disease, primarily affecting individuals aged 50-75, and is characterized by rapid cognitive decline and neurological deterioration. The genetic factors influencing Familial Creutzfeldt-Jakob Disease, which accounts for a smaller yet significant portion of the cases, have led to targeted research initiatives. On the other hand, Variant Creutzfeldt-Jakob Disease, linked to dietary exposure to BSE, is deemed an emerging concern, prompting health authorities to monitor risks associated with food sources. This growing emphasis on vCJD reflects a shift in focus within the healthcare community, emphasizing the need for preventive measures and enhanced public health strategies.

By Diagnosis Method: Electroencephalogram (Largest) vs. Brain Biopsy (Fastest-Growing)

The diagnosis methods for Creutzfeldt-Jakob disease in South America comprise key techniques such as Electroencephalogram (EEG), Magnetic Resonance Imaging (MRI), Cerebrospinal Fluid Tests, and Brain Biopsy. Among these, the Electroencephalogram holds the largest market share, recognized for its effectiveness in identifying abnormal brain activity associated with the disease. MRI follows closely, offering detailed imaging capabilities that aid in diagnosis, while Cerebrospinal Fluid Tests and Brain Biopsy are essential but less frequently utilized due to their invasive nature and requirement for specialized skills. Growth trends in the diagnosis method segment indicate an increasing reliance on non-invasive techniques, leading to a rise in the use of MRI and Electroencephalogram. The ongoing advancements in imaging technology enhance diagnostic accuracy, which fosters market growth. Moreover, the development of minimally invasive procedures for Cerebrospinal Fluid Tests is likely to contribute to its acceptance. Rising awareness and better access to neurological care in South America are key drivers steering the market towards expanded adoption of these diagnostic methods.

Electroencephalogram (Dominant) vs. Brain Biopsy (Emerging)

Electroencephalogram (EEG) remains the dominant diagnosis method for Creutzfeldt-Jakob disease, leveraging its ability to detect electrical activity in the brain crucial for identifying abnormal patterns. It is well-established, cost-effective, and widely accessible across healthcare settings in South America. In contrast, the Brain Biopsy is an emerging method, gaining traction despite its invasive nature. While traditionally seen as a last resort due to associated risks, evolving surgical techniques and the need for accurate confirmation of diagnosis are driving interest in its application. As healthcare providers prioritize accuracy, the demand for Brain Biopsy is expected to rise, influencing how clinicians approach disease confirmation.

By Treatment Approach: Supportive Care (Largest) vs. Experimental Therapies (Fastest-Growing)

The treatment approach segment reveals that supportive care dominates the landscape, holding a significant share as it forms the backbone of current care protocols. This approach prioritizes the comfort and quality of life for patients and is integral in managing symptoms associated with creutzfeldt jakob disease. Experimental therapies, while currently smaller in market share, are rapidly gaining traction as innovative research unfolds, catering to the urgent need for effective interventions. Growth trends in this segment are predominantly driven by advances in medical research and clinical trials exploring new treatment modalities. The rising prevalence of neurodegenerative conditions is prompting a push for innovative therapeutic strategies, thereby fostering a competitive environment. Additionally, increased funding for research initiatives focusing on rare diseases is paving the way for more experimental therapies to enter the market, making it a focal point for future growth.

Supportive Care (Dominant) vs. Experimental Therapies (Emerging)

Supportive care represents the dominant force in the treatment approach segment, characterized by its focus on alleviating symptoms and providing comprehensive assistance to affected individuals and their families. This approach hinges on multidisciplinary teams offering psychological support, nutritional guidance, and pain management to enhance patient comfort. Conversely, experimental therapies, though classified as emerging, are gathering momentum due to breakthroughs in understanding the pathology of creutzfeldt jakob disease. These therapies, often in the trial phase, aim to address the root causes of the disease, showing promise in altering its course. The juxtaposition of these two approaches highlights a critical phase in treatment, underscoring both the necessity of existing care strategies and the potential of future innovations.

By End User: Hospitals (Largest) vs. Diagnostic Laboratories (Fastest-Growing)

The market for the End User segment is predominantly held by Hospitals, which command the largest share in terms of service delivery for Creutzfeldt Jakob Disease cases. Their extensive infrastructure and specialized staff enable them to provide comprehensive care and treatment for patients, making them a preferred choice among patients and healthcare practitioners alike. In contrast, Diagnostic Laboratories, while smaller in market share, are experiencing rapid growth as the demand for early diagnosis and testing increases, driven by rising awareness and the need for timely interventions. The growth trends within this segment are influenced by increased healthcare spending and advancements in diagnostic technologies. Hospitals are enhancing their capabilities to manage complex cases, while Diagnostic Laboratories are swiftly integrating innovative methodologies to improve diagnostic accuracy and turnaround times. Additionally, the ongoing research within Research Institutes contributes to the evolution of testing procedures and treatment protocols, ensuring a collaborative approach to combating Creutzfeldt Jakob Disease and fostering a healthier future for affected populations.

Hospitals (Dominant) vs. Diagnostic Laboratories (Emerging)

Hospitals play a dominant role in the care continuum for patients with Creutzfeldt Jakob Disease, leveraging advanced clinical facilities and experienced healthcare teams to provide critical interventions. They are well-equipped to handle emergencies and complex cases, offering a range of services from initial diagnosis to end-of-life care. In contrast, Diagnostic Laboratories are emerging as essential players in the healthcare landscape, capitalizing on the growing need for precise and timely diagnostic tests. These laboratories are increasingly adopting sophisticated technologies to enhance their testing capabilities and accuracy, ensuring that healthcare professionals have access to reliable information for decision-making. Their ability to rapidly adapt to new challenges positions them as indispensable contributors to managing and understanding Creutzfeldt Jakob Disease.

Get more detailed insights about South America Creutzfeldt Jakob Disease Market

Regional Insights

Brazil : Strong Demand and Infrastructure Support

Brazil holds a significant 16.0% market share in the South American creutzfeldt jakob disease (CJD) market, driven by increasing awareness and advancements in diagnostic technologies. Key growth drivers include government initiatives aimed at enhancing healthcare infrastructure and regulatory support for innovative treatments. The demand for CJD diagnostics is rising, influenced by an aging population and improved healthcare access, which is further supported by investments in research and development.

Mexico : Growing Awareness and Investment

With a 10.0% market share, Mexico is witnessing a gradual increase in the CJD market, fueled by rising public awareness and investment in healthcare. The government has initiated programs to enhance diagnostic capabilities and promote research on prion diseases. Demand is growing, particularly in urban areas, as healthcare facilities expand and improve their services, leading to better patient outcomes and increased consumption of diagnostic tools.

Argentina : Focus on Research and Diagnostics

Argentina accounts for an 8.0% share of the CJD market, characterized by a strong focus on research and development in prion diseases. The government is actively promoting initiatives to improve diagnostic capabilities and treatment options. Demand trends indicate a growing need for advanced diagnostic tools, particularly in major cities like Buenos Aires and Córdoba, where healthcare facilities are increasingly equipped to handle rare diseases.

Rest of South America : Diverse Opportunities and Challenges

The Rest of South America holds a 6.0% market share in the CJD landscape, with varying levels of awareness and healthcare infrastructure across countries. Growth is driven by regional collaborations and initiatives aimed at improving healthcare access. Demand for CJD diagnostics is emerging, particularly in countries like Chile and Colombia, where healthcare systems are evolving to address rare diseases more effectively.

South America Creutzfeldt Jakob Disease Market Regional Image

Key Players and Competitive Insights

The competitive dynamics within the creutzfeldt jakob-disease market in South America reflect a landscape characterized by innovation and strategic partnerships. Key growth drivers include the increasing prevalence of prion diseases, heightened awareness among healthcare professionals, and advancements in diagnostic technologies. Major players such as Grifols (ES), Karyopharm Therapeutics (US), and Bio-Rad Laboratories (US) are actively shaping the market through their distinct operational focuses. Grifols (ES) emphasizes innovation in plasma-derived therapies, while Karyopharm Therapeutics (US) is concentrating on developing novel therapeutics targeting prion diseases. Bio-Rad Laboratories (US) is enhancing its diagnostic capabilities, thereby collectively influencing the competitive environment through a blend of technological advancements and strategic positioning.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The market structure appears moderately fragmented, with several players vying for market share. However, the collective influence of key players is significant, as they leverage their resources and expertise to establish a competitive edge. This fragmentation allows for niche players to emerge, yet the dominance of established firms remains a critical factor in shaping market dynamics.

In October 2025, Grifols (ES) announced a strategic partnership with a leading South American research institution to develop advanced diagnostic tools for prion diseases. This collaboration is expected to enhance Grifols' product offerings and strengthen its position in the region by leveraging local expertise and resources. Such partnerships are indicative of a broader trend where companies seek to integrate local knowledge into their operational strategies, thereby fostering innovation and improving patient outcomes.

In September 2025, Karyopharm Therapeutics (US) received regulatory approval for its novel therapeutic agent aimed at treating prion diseases. This approval marks a significant milestone for the company, as it positions Karyopharm as a frontrunner in the development of targeted therapies. The strategic importance of this event lies in its potential to address unmet medical needs in the region, thereby enhancing Karyopharm's market presence and driving future growth.

In August 2025, Bio-Rad Laboratories (US) launched a new diagnostic kit specifically designed for the early detection of prion diseases. This product introduction is crucial as it aligns with the growing demand for rapid and accurate diagnostic solutions. By enhancing its diagnostic portfolio, Bio-Rad is likely to capture a larger market share and solidify its reputation as a leader in the field.

As of November 2025, current trends in the creutzfeldt jakob-disease market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) in diagnostics and treatment. Strategic alliances are playing a pivotal role in shaping the competitive landscape, as companies collaborate to enhance their technological capabilities and expand their market reach. Looking ahead, competitive differentiation is expected to evolve, with a pronounced shift from price-based competition to a focus on innovation, technology, and supply chain reliability. This transition underscores the importance of developing robust, sustainable solutions that meet the evolving needs of healthcare providers and patients alike.

Key Companies in the South America Creutzfeldt Jakob Disease Market market include

Industry Developments

Recent developments in the South America Creutzfeldt-Jakob Disease Market have highlighted significant advancements and challenges. In October 2023, Gilead Sciences announced a comprehensive initiative aimed at enhancing diagnostic capabilities for rare neurological diseases, including Creutzfeldt-Jakob Disease. Simultaneously, Novartis and Merck have been collaborating on Research and Development projects to better understand prion diseases and explore novel therapeutic pathways. 

There has been an observed increase in market valuation for companies such as Pfizer and Roche, largely attributed to heightened awareness and diagnostic improvement efforts in the region. Additionally, in September 2023, Takeda revealed a new treatment approach under evaluation in clinical trials, stirring interest in the medical community across South America. 

Over the past few years, several public health initiatives have been launched by the South American governments to address prion diseases. The involvement of larger pharmaceutical entities has been a critical factor in increasing investment within this niche market, shaping a landscape that is increasingly focused on innovative treatment strategies and diagnostics for Creutzfeldt-Jakob Disease.

Future Outlook

South America Creutzfeldt Jakob Disease Market Future Outlook

The creutzfeldt jakob-disease market is projected to grow at a 5.88% CAGR from 2024 to 2035, driven by advancements in diagnostics, increased awareness, and enhanced treatment options.

New opportunities lie in:

  • Development of targeted therapies for specific CJD variants.
  • Expansion of telemedicine services for remote patient monitoring.
  • Investment in genetic research to identify at-risk populations.

By 2035, the market is expected to achieve substantial growth, driven by innovative solutions and strategic investments.

Market Segmentation

South America Creutzfeldt Jakob Disease Market Type Outlook

  • Sporadic Creutzfeldt-Jakob Disease
  • Familial Creutzfeldt-Jakob Disease
  • Iatrogenic Creutzfeldt-Jakob Disease
  • Variant Creutzfeldt-Jakob Disease

South America Creutzfeldt Jakob Disease Market End User Outlook

  • Hospitals
  • Diagnostic Laboratories
  • Research Institutes

South America Creutzfeldt Jakob Disease Market Diagnosis Method Outlook

  • Electroencephalogram
  • Magnetic Resonance Imaging
  • Cerebrospinal Fluid Tests
  • Brain Biopsy

South America Creutzfeldt Jakob Disease Market Treatment Approach Outlook

  • Supportive Care
  • Experimental Therapies
  • Symptomatic Treatment

Report Scope

MARKET SIZE 202440.0(USD Million)
MARKET SIZE 202542.35(USD Million)
MARKET SIZE 203575.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.88% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Grifols (ES)", "Karyopharm Therapeutics (US)", "Prionics AG (CH)", "Bio-Rad Laboratories (US)", "Thermo Fisher Scientific (US)", "Fujirebio (JP)", "CureVac (DE)", "Sangamo Therapeutics (US)"]
Segments CoveredType, Diagnosis Method, Treatment Approach, End User
Key Market OpportunitiesAdvancements in diagnostic technologies enhance early detection in the creutzfeldt jakob-disease market.
Key Market DynamicsRegulatory changes and technological advancements drive innovation in the Creutzfeldt Jakob disease market in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Creutzfeldt-Jakob Disease Market in 2024?

The South America Creutzfeldt-Jakob Disease Market is expected to be valued at 1.39 billion USD in 2024.

What will be the market size of the South America Creutzfeldt-Jakob Disease Market by 2035?

By 2035, the overall market is projected to reach approximately 3.77 billion USD.

What is the expected CAGR for the South America Creutzfeldt-Jakob Disease Market between 2025 and 2035?

The expected compound annual growth rate (CAGR) for the market from 2025 to 2035 is 9.469%.

Which region is expected to dominate the South America Creutzfeldt-Jakob Disease Market?

Brazil is anticipated to hold the largest market share in the region, with a market value of 0.45 billion USD in 2024.

What are the expected market values for the Familial Creutzfeldt-Jakob Disease segment by 2035?

The Familial Creutzfeldt-Jakob Disease segment is projected to reach a value of 0.75 billion USD by 2035.

What is the market value forecast for the Iatrogenic Creutzfeldt-Jakob Disease segment in 2024?

In 2024, the Iatrogenic Creutzfeldt-Jakob Disease segment is expected to be valued at 0.23 billion USD.

Who are the key players in the South America Creutzfeldt-Jakob Disease Market?

Major players in the market include Gilead Sciences, Novartis, Merck, and Sanofi among others.

What is the projected market value for the Variant Creutzfeldt-Jakob Disease segment in 2035?

The market value for the Variant Creutzfeldt-Jakob Disease segment is expected to reach 0.4 billion USD by 2035.

What will be the market value of the Rest of South America segment in 2035?

The Rest of South America segment is projected to have a market value of approximately 1.513 billion USD by 2035.

How much is Mexico's share in the South America Creutzfeldt-Jakob Disease Market in 2024?

Mexico's share in the market is expected to be valued at 0.3 billion USD in 2024.

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