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Botulinum Toxin Market Research Report Information By Product (Botulinum Toxin A and Botulinum Toxin B), By Application (Medical and Aesthetic), By Gender (Female and Male), By Age Group (13-19, 20-29, 30-39, 40-54, and 55 & Above), By End User (Hospitals, Dermatology Clinics, and Spas & Cosmetic Centers) and By Region (North America, Europe, Asia-Pacific, and Rest of the World) –Market Forecast Till 2032


ID: MRFR/HC/7095-CR | 151 Pages | Author: Kinjoll Dey| February 2021

Global Botulinum Toxin Market Overview


Botulinum Toxin Market Size was valued at USD 3.5 Billion in 2023. The Botulinum Toxin market industry is projected to grow from USD 3.91 Billion in 2024 to USD 8.7 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 10.50% during the forecast period (2024 - 2032). Growing aesthetic and cosmetic applications, medical applications, advancements in botulinum toxin formulations, rising disposable income, increasing awareness and acceptance, growing aging population, technological advancements in delivery systems, expanding market access, shift towards minimally invasive procedures, increasing number of aesthetic clinics and providers, are the key market drivers enhancing the market growth.


Botulinum Toxin Market


Source Secondary Research, Primary Research, MRFR Database and Analyst Review


The rise of the botulinum toxin industry will be spurred by the fact that Botox can be used for both medicinal and cosmetic purposes. Positive market growth is expected to result from its use in treating critical and chronic conditions such spasticity, migraine, and cervical dystonia. Potential therapeutic uses for this toxin are estimated in the hundreds, and there are already over 100 approved uses for therapeutic toxins that get insurance reimbursement. The increasing demand for therapeutic applications has prompted major market participants to invest considerably in R&D. This is expected to create several potential prospects for the industry in the future.


In 2024, Hugel America, Inc., a branch of Hugel Inc., a world-renowned leader in the medical aesthetics sector, declared that the FDA had approved Letybo, a neurotoxic, for the treatment of moderate-to-severe glabellar (frown) lines in adults. Hugel intends to launch to aesthetic clinicians in the upcoming months, expediting its transition for approved medical use. Positive outcomes from three completed phase III trials that enrolled over 1,000 participants in the U.S. and Europe lend credence to the FDA's approval1. For seven years running, this type A botulinum toxin has been the top neurotoxic brand in South Korea, one of the most vibrant aesthetic markets in the world.


Medytox declared in 2023 that NEWMECO, a subsidiary, has introduced NEWLUX, a botulinum toxin product of the next generation. For NEWLUX, a botulinum toxin formulation that removes the use of animal-derived components in the raw material production process, NEWMECO got product certification from the Ministry of Food and Drug Safety in August. This effectively prevents potential allergic reactions brought on by animal antigens.


 


Demand for non-invasive and minimally invasive cosmetic procedures, as well as expanding botulinum toxin uses and research and development spending, are key drivers of the global botulinum toxin market. In addition, the development of botulinum toxin injection techniques and the popularity of botox treatment have had a sizable effect on the management of cluster headaches and migraines brought on by stress.


The market is also responding with new suppliers, lower prices, and more accommodating reimbursement rules. In order to improve their aesthetics and the therapeutic effects for their patients, the market's major companies are putting a premium on constant innovation and expanding their product line.


The providers of dermatological services and other non-invasive technologies were seriously impacted by the uptick in demand for aesthetic operations requiring minimal to no surgery. There is a rising need for these medicines, thus several pharmaceutical firms working in this area are ramping up production.


December 2022, Gufic Biosciences announced the release of their botulinum toxin type A injection, dubbed "Zarbot." The drug was co-developed and manufactured by the United States-based company Prime Bio. The announcement was made during a Mumbai event, and the statement attributed its release to Indian doctors Dirk Dressler, Balaram Singh, and others. Thin film formulation and improved stability in comparison to other botulinum toxin brands are the consequences of using a pure Hall strain and patented technology in the injection's production.


Botulinum Toxin Market Trends



  • Increased medical application of botox is driving the market growth


The market for botulinum toxin has grown significantly due in large part to medical applications. While Botulinum Toxin, also known as Botox, is well-known for its cosmetic usage, its medical applications have grown quickly over time. The development of novel treatment alternatives and the identification of its therapeutic advantages have spurred this expansion and raised demand from patients and healthcare professionals alike. Botulinum toxin is used in medicine to treat a variety of neurological problems. Botulinum Toxin injections have demonstrated impressive improvement in conditions like cervical dystonia, a neurological illness characterized by aberrant neck muscle contractions and involuntary head movements. By preventing the nerve signals that trigger muscular spasms, the toxin relieves patients of their incapacitating symptoms. Similarly, Botulinum Toxin has been beneficial in treating hemifacial spasm and blepharospasm (uncontrolled blinking), improving patients' quality of life and decreasing their reliance on other drugs.


Additionally effective in treating hyperhidrosis, a disorder marked by excessive sweating, is botulinum toxin. Botulinum toxin reduces perspiration when applied to troublesome regions like the underarms, palms, or soles of the feet. It does this by blocking the nerve signals that activate sweat glands. For those with hyperhidrosis-related social and functional deficits, this has been a game-changer because it provides them with respite from their disease and enhances their confidence. Botulinum toxin has been used to treat neurogenic detrusor overactivity (NDO) and overactive bladder (OAB) in the field of urology. Urinary urgency and incontinence result from the uncontrollable contraction of the bladder muscles under these circumstances. Injections of botulinum toxin reduce symptoms and improve patients' general quality of life by relaxing the muscles in the bladder wall.


The ability of Botulinum Toxin to cure a variety of eye problems further demonstrates its adaptability. Injecting the toxin into particular eye muscles can be used to treat strabismus, or crossed eyes, in order to straighten the eyes and enhance eyesight. Additionally, facial nerve diseases like facial nerve palsy can be treated with botulinum toxin to enhance facial symmetry and function. Additionally, Botulinum Toxin has demonstrated potential in treating a number of pain problems, including chronic pelvic pain and myofascial pain syndrome. The toxin can reduce muscular spasms and target specific trigger points to relieve pain and enhance patients' general health.


As clinical trials and studies investigate Botulinum Toxin's potential to cure a variety of illnesses, its medical uses are continuously expanding. Both patients and healthcare professionals find it to be a desirable therapy choice because to its low risk and non-invasive nature. The demand for Botulinum Toxin is anticipated to continue driving market expansion as more medical professionals become familiar with its efficacy and safety. Thus, driving the Botulinum Toxin market revenue.


Botulinum Toxin Market Segment Insights


Botulinum Toxin Product Insights


The Botulinum Toxin market segmentation, based on Product, includes Botulinum Toxin A and Botulinum Toxin B. The botulinum toxin A segment dominated the market in 2022 due to advantages including low pain, no blood loss, and lack of scarring after the surgery, botulinum toxin A is expected to develop at a large rate due to an increase in consumer desire. The treatment of persistent migraine, tension-type headache, and other primary neurological illnesses using botulinum toxin type-A is becoming more common.


Botulinum Toxin Application Insights


The Botulinum Toxin market segmentation, based on Application, includes Medical and Aesthetic. The medical category generated the most income in 2022. The therapeutic benefits of the botulinum toxin have been growing as a result of better understanding of its various mechanisms of action and molecular activity. Treatments and preventative measures for conditions like hyperhidrosis, chronic headaches, and overactive bladders include Botox procedures.


Botulinum Toxin Gender Insights


The Botulinum Toxin market segmentation, based on Gender, includes Female and Male. The female segment dominated the market in 2022. The rise in female skin rejuvenation trends in middle age and the rise in aesthetic surgery rates are to blame for this.


Botulinum Toxin Age Group Insights


The Botulinum Toxin market segmentation, based on Age Group, includes 13-19, 20-29, 30-39, 40-54, and 55 & Above. The 40-54 segment dominated the market in 2022. The adoption rate of botulinum toxin in this market has increased due to the growing use of different botulinum toxin types to reduce the indications of aging.


Botulinum Toxin End User Insights


The Botulinum Toxin market segmentation, based on End User, includes Hospitals, Dermatology Clinics, and Spas & Cosmetic Centers. The hospitals segment dominated the market in 2022. The expansion of this market is attributed to an increase in the number of hospitals offering cutting-edge treatment and facilities in both developed and emerging nations, as well as to growing public awareness of aesthetic operations.


Figure 1 Botulinum Toxin Market, by gender, 2023 & 2032 (USD Billion)


Botulinum Toxin Market, by gender, 2022 & 2032


Source Secondary Research, Primary Research, MRFR Database and Analyst Review


June 2023, Nuceiva (botulinum toxin type A) has begun its commercial introduction in Italy by performance beauty company Evolus, Inc. Customers can now place orders for immediate shipment of the goods. Nuceiva has been granted approval by the European Commission for the temporary treatment of moderate to severe frown lines (glabellar lines) in adults younger than 65 years old whose appearance of these lines causes significant psychological distress.


Botulinum Toxin Regional Insights


By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North America Botulinum Toxin Market dominated this market in 2022 (45.80%). The reasons that contribute to the region's success include the rising number of product releases, the presence of large corporations, and the rising adoption of these practices among locals. For instance, the International Society of Aesthetic Plastic Surgery estimates that over 2,520,000 botulinum toxin operations were carried out in the United States in 2021. Additionally helping the region flourish is the spike in product launches brought on by rising regulatory approvals for these drugs' therapeutic uses. Further, the U.S. Botulinum Toxin market held the largest market share, and the Canada Botulinum Toxin market was the fastest growing market in the North America region.


Further, the major countries studied in the market report are The U.S., Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2 BOTULINUM TOXIN MARKET SHARE BY REGION 2022 (USD Billion)


BOTULINUM TOXIN MARKET SHARE BY REGION 2022


Source Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe Botulinum Toxin market accounts for the second-largest market share. One of the key drivers of the expansion of the European region is the increased spending on R&D projects to introduce new products. For instance, 208,764 nonsurgical cosmetic operations, including 75,348 botulinum toxin procedures, were carried out in Spain in accordance with the International Society of Aesthetic Plastic Surgery (ISAPS) (2021). Further, the German Botulinum Toxin market held the largest market share, and the UK Botulinum Toxin market was the fastest growing market in the European region


The Asia-Pacific Botulinum Toxin Market is expected to grow at the fastest CAGR from 2024 to 2032 because chronic diseases are becoming more common and prevalent, and because more people are becoming mindful of their physical appearance. The majority of these treatments are carried out in dermatology and specialized clinics, which is fueling the segment's expansion. Moreover, China’s Botulinum Toxin market held the largest market share, and the Indian Botulinum Toxin market was the fastest growing market in the Asia-Pacific region.


Botulinum Toxin Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development in order to expand their product lines, which will help the Botulinum Toxin market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Botulinum Toxin industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the Botulinum Toxin industry to benefit clients and increase the market sector. In recent years, the Botulinum Toxin industry has offered some of the most significant advantages to medicine. Major players in the Botulinum Toxin market, including AbbVie Inc., Eisai Co. Ltd., Evolus Inc, Galderma, Hugel Inc., Hugh Source International Ltd and others, are attempting to increase market demand by investing in research and development operations.


AbbVie Inc. (AbbVie), a specialty biopharmaceutical company, finds, develops, produces, and distributes medications to treat chronic and complex illnesses. Its drugs are approved for the treatment of serious medical conditions like cancer, neurological disorders, rheumatoid arthritis, endometriosis pain, pediatric Crohn's disease, metabolic and rheumatological diseases, skin problems, and others. The pipeline diseases that AbbVie is promoting also include Crohn's disease, Parkinson's disease, viral illnesses, wet AMD, different cancers, neurological disorders, aesthetic issues, and other autoimmune diseases. The business offers its goods directly to wholesalers, distributors, healthcare facilities, governmental entities, specialty pharmacies, and independent retailers through its own distribution centers and open warehouses all around the world. The headquarters of AbbVie are located in North Chicago, Illinois, in the US.


Galderma SA (Galderma) develops and markets cosmetic and pharmaceutical skin care items. For a variety of skin conditions, including acne, rosacea, psoriasis, nail mycosis, pigmentary disorders, skin cancer, atopic dermatitis, and sun protection, the company sells prescription drugs and cosmetic procedures. Some of its well-known trademarks are Epiduo, Differin, Oracea, Loceryl, Metvix, Azzalure/Dysport, Mirvaso, Soolantra, Restylane, Cetaphil, and Emervel. The company has production sites and centers for research and development across North and Latin America, the Middle East, Europe, Africa, Asia-Pacific, and all of these places in between. Galderma's corporate headquarters are in Zug, Switzerland.


Key Companies in the Botulinum Toxin market include



  • AbbVie Inc

  • Eisai Co., Ltd.

  • Evolus Inc

  • Galderma

  • Hugel, Inc.

  • Hugh Source International Ltd 


Botulinum Toxin Industry Developments


In 2024 Hugel America, Inc., a branch of Hugel Inc., a world-renowned leader in the medical aesthetics sector, declared that the FDA had approved Letybo, a neurotoxic, for the treatment of moderate-to-severe glabellar (frown) lines in adults. Hugel intends to launch to aesthetic clinicians in the upcoming months, expediting its transition for approved medical use. Positive outcomes from three completed phase III trials that enrolled over 1,000 participants in the U.S. and Europe lend credence to the FDA's approval1. For seven years running, this type A botulinum toxin has been the top neurotoxic brand in South Korea, one of the most vibrant aesthetic markets in the world.


Medytox declared in 2023 that NEWMECO, a subsidiary, has introduced NEWLUX, a botulinum toxin product of the next generation. For NEWLUX, a botulinum toxin formulation that removes the use of animal-derived components in the raw material production process, NEWMECO got product certification from the Ministry of Food and Drug Safety in August. This effectively prevents potential allergic reactions brought on by animal antigens.


July 2022 Fastox Pharma debuted the long-lasting botulinum toxin, known as LAST technology, during the "Toxins 2022 International Conference." Fastox discovered that the commencement of action of botulinum toxin type A (BoNT/A) should be accelerated by the addition of fast-acting myorelaxant drugs.


October 2022 Galderma and National Breast Cancer Foundation Inc. (NBCF) kept on their collaboration. Breast cancer survivors who had Restylane, Dysport (abobotulinumtoxinA), and/or Sculptra during Breast Cancer Awareness Month were profiled in a promotion on Galderma's social media channels.


August 2022 The collaboration between Medytox and Bloomage Biotechnology has ended. According to Bloomage Biotechnology, since the joint venture agreement was signed, Medytox has never offered goods made by Medybloom China BTX for sale.


Botulinum Toxin Market Segmentation


Botulinum Toxin Product Outlook



  • Botulinum Toxin A

  • Botulinum Toxin B


Botulinum Toxin Application Outlook



Botulinum Toxin Gender Outlook



  • Female

  • Male


Botulinum Toxin Age Group Outlook



  • 13-19

  • 20-29

  • 30-39

  • 40-54

  • 55 & Above


Botulinum Toxin End User Outlook



  • Hospitals

  • Dermatology Clinics

  • Spas & Cosmetic Centers


Botulinum Toxin Regional Outlook




  • North America

    • US.

    • Canada




  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe




  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific




  • Rest of the World

    • Middle East

    • Africa

    • Latin America



Botulinum Toxin Report Scope
Report Attribute/Metric Details
Market Size 2023 USD 3.5 Billion
Market Size 2024 USD 3.91 Billion
Market Size 2032 USD 8.7 Billion
Compound Annual Growth Rate (CAGR) 10.50% (2024-2032)
Base Year 2023
Market Forecast Period 2024-2032
Historical Data 2018- 2022
Market Forecast Units Value (USD Billion)
Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered Product, Application, Gender, Age Group, End User, and Region
Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
Countries Covered The U.S., Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled AbbVie Inc., Eisai Co. Ltd., Evolus Inc, Galderma, Hugel Inc., Hugh Source International Ltd
Key Market Opportunities R&D efforts are expanding, and there are more and more therapeutic and esthetic applications.
Key Market Dynamics Demand for minimally invasive cosmetic procedures is increasing.


Frequently Asked Questions (FAQ) :

The Botulinum Toxin market size was valued at USD 3.5 Billion in 2023.

The market is projected to grow at a CAGR of 10.50% during the forecast period, 2024-2032.

North America had the largest share in the  market

The key players in the market are AbbVie Inc., Eisai Co. Ltd., Evolus Inc, Galderma, Hugel Inc., and Hugh Source International Ltd.

The Botulinum Toxin A category dominated the market in 2023.

The female had the largest share in the market.

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