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Dental Bone Graft Substitutes Companies

Dental bone graft substitutes companies specialize in the development and manufacturing of products used in dental procedures to replace or regenerate bone in the oral and maxillofacial region. These products are crucial for various applications, including dental implant procedures, ridge augmentation, and periodontal surgeries.

Dental Bone Graft Substitutes Companies.jpgLatest Dental Bone Graft Substitutes Companies Update



  • Jan 2023: By the agreement, Asahi Kasei Medical expands its bioprocess business by including a biopharmaceutical contractual development and production organization (CDMO). Bionova is a company that develops and produces treatments using recombinant proteins. The acquisition's closing is contingent upon receiving the necessary regulatory permissions. With over 100 workers, Bionova is a portfolio company of Great Point Partners, a private investment organization with its headquarters in Greenwich, Connecticut, concentrating on the healthcare sector. According to Asahi Kasei Medical, process development and GMP manufacturing operations are essential to the general business success of biopharma customers as well as the introduction of new medications. Bionova is well-known in the industry for its process development skills.




  • Nov 2023: In comparison to traditional spinal cord stimulation (SCS) therapy, patients with chronic back pain can see a considerable reduction in pain using Medtronic's differential target multiplexed (DTM) SCS therapy, according to study data released by the company. The 12-month trial, which involved 20 US facilities, compared Medtronic's DTM SCS program to traditional spinal cord stimulation therapy and discovered that patients with various degenerative conditions could experience much less pain using the DTM SCS program. The NOVA research was an open-label, prospective, multi-center experiment that aimed to enroll patients with non-surgically treated herniated disc (HD), degenerative disc disease (DDD), or radicular pain syndrome (RPS) and compare the DTM SCS system to traditional spinal cord stimulation.


List of Dental Bone Graft Substitutes Key companies in the market


  • Orthogen LLC (US)




  • LifeNet Health (US)




  • Dentium (South Korea)




  • Zimmer Biomet Dental (US)




  • Medtronic Plc (Ireland)




  • Institut Straumann AG (Switzerland)




  • Dentsply Sirona (US)




  • Geistlich Pharma AG (Switzerland)




  • Biohorizons Iph Inc. (US)



Global Dental Bone Graft Substitutes Market Overview


The dental bone graft substitutes market size was valued at USD 1.1 billion in 2023 and is projected to grow from USD 1.2 Billion in 2024 to USD 1.73 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 4.68% during the forecast period (2024 - 2032). The growing number of dental visits and use of synthetic and biocompatible grafts in dental procedures are just a few market drivers that are propelling the market. 


Dental Bone Graft Substitutes Market Overview1


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Dental Bone Graft Substitutes Market Trends



  • Growing prevelance of dental diorders to aid market growth


Most oral health conditions can be treated when young and are largely preventable. Dental caries (tooth decay), periodontal diseases, tooth loss, and oral cancers account for most cases. Orofacial clefts, noma (a severe gangrenous illness that begins in the mouth and primarily affects children), and oro-dental trauma are additional oral conditions of public health significance. According to the WHO Oral Health Status Report (2022), nearly 3.5 billion people worldwide suffer from oral diseases, with three out of every four individuals residing in middle-income nations. Five hundred fourteen million children worldwide suffer from primary tooth decay, while 2 billion adults are thought to have permanent tooth decay. With increasing urbanization and changes in livable conditions, the prevalence of major oral diseases is rising globally. This is primarily caused by inadequate exposure to fluoride (found in toothpaste and water supplies), accessibility to and affordability of foods high in sugar, and a lack of access to oral health care services in the community. Products that contribute to oral health problems and other NCDs are increasingly consumed due to the marketing of sugar-rich foods and beverages and tobacco and alcohol. Such a growing prevalence of various dental disorders is expected to drive the market CAGR.


Figure 1: Prevalence of total dental caries and untreated dental caries in primary or permanent teeth among youth aged 2–19 years, by age: United States, 2015–2016Prevalence of total dental caries and untreated dental caries in primary or permanent teeth among youth aged 2–19 years, by age: United States, 2015–2016


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


The rising geriatric population is also a key market driver as older adults are more susceptible to dental disorders. According to the US Census, there will be 98 million US adults who are 65 or older in 2060 or 24% of the entire population. It has been estimated that the prevalence of dental disorders is higher among older people. According to the Centers for Disease Control and Prevention, one in five adults (or 96% of adults 65 years of age and older) have untreated tooth decay. Nearly one in five adults 65 and older has lost every tooth. Adults 75 and older (26%) experience twice as many complete tooth losses as those 65 to 74 (13%). Since one out of every four dental implants requires this well-accepted procedure for reversing dental bone loss, this presents an opportunity for dental bone graft substitutes. Thus, this aspect is expected to accelerate Dental Bone Graft Substitutes market revenue globally.


Moreover, a growing research study to find an alternative for a dental bone graft is also anticipated to surge the market growth during the forecast period. Research and development in materials, design, and fabrication technologies have advanced over time to produce successful and durable dental implants to replace missing teeth. Due to improvements in dental implantology and the increasing need to repair craniofacial bony defects, the use of bone grafts and replacements has significantly increased in dentistry in recent years. According to current data, 2.2 million bone graft procedures are estimated to be carried out annually globally, with the cost of those procedures expected to reach USD 664 million by 2021. Additionally, it is predicted that the number of surgical techniques for treating bony defects will increase by about 13% annually.


Dental Bone Graft Substitutes Market Segment Insights


Dental Bone Graft Substitutes Type Insights


The Dental Bone Graft Substitutes market segmentation, based on type, includes allograft, xenograft, and alloplast. The xenograft segment held the majority share in 2022 in the Dental Bone Graft Substitutes market data. Xenografts are obtained from pigs (porcine) or cows (bovine) and are sterilised before being carefully cleaned and prepared for implantation into the human body. In dentistry, deproteinized bovine bone is the most typical source of xenograft materials. The strategic actions taken by market participants are also assisting in the market's expansion.


March 2022:Fredun Pharmaceuticals permission to produce Xenografts for a range of dental and orthopaedic surgical appliances form the Central Drugs Standard Control Organization (COSCO), India. The Company plans to expand its reach within the dental community in India by doing this. Due to the increased use of grafts by doctors, the company is expanding its product line with this new addition in order to capitalise on the expanding market.


Figure 2: Dental Bone Graft Substitutes Market, by Type, 2023 & 2032 (USD Billion)


Dental Bone Graft Substitutes Market, by Type


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Dental Bone Graft Substitutes Application Insights


The Dental Bone Graft Substitutes market segmentation, based on application, includes Ridge augmentation, sinus lift, socket preservation, and periodontal defect. The ridge augmentation segment dominated the market growth in 2022 and is projected to be the faster-growing segment during the forecast period, 2022-2030. The growth of this market is being driven by an increase in dental implant surgeries and public awareness of the importance of oral health care. Additionally, the burden of dental diseases is rising, and technological developments in dentistry are supporting segment growth.


Dental Bone Graft Substitutes End User Insights


The Dental Bone Graft Substitutes market data, based on end user, includes dental clinics and hospitals. The dental clinics segment dominated the Dental Bone Graft Substitutes market revenue in 2022 and is projected to be the faster-growing segment during the forecast period, 2022-2030. A growing number of dental clinics coupled with the rising prevalence of dental diseases are among the key factors propelling the growth of this segment. Moreover, due to their convenience and easy accessibility of surgeons, dental clinics are becoming more and more popular as the number of dental graft surgeries each year increases.


Dental Bone Graft Substitutes Regional Insights


By region, the study provides the market insights for dental bone graft substitutes into North America, Europe, Asia-Pacific and Rest of the World. North America Dental Bone Graft Substitutes market accounted for USD 0.4 billion in 2022 with a share of around 45.80% and is expected to exhibit a significant CAGR growth during the study period. The main factors influencing the region's growth are rising healthcare costs, increased awareness of commercially available advanced products, and accessibility to an advanced healthcare system. Fuether, growing prevelance of dental disease is also playing a pivotal factor in the markets growth. According to the Center for Disease Control and Prevention, in the United States, untreated tooth decay affects 26% of adults.


Further, the major countries studied in the market report for dental bone graft substitutes are: The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 3: DENTAL BONE GRAFT SUBSTITUTES MARKET SHARE BY REGION 2022 (%) 


DENTAL BONE GRAFT SUBSTITUTES MARKET SHARE BY REGIONSource: Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe Dental Bone Graft Substitutes market accounts for the second-largest market share. The demand for medical and dental tourism is on the rise, dental diseases are becoming more prevalent, and dental technology is advancing, which are all contributing factors to the growth in this area. The market is expanding due to the rising burden of dental diseases. Moreover, UK Dental Bone Graft Substitutes market held the largest market share, and the Germany Dental Bone Graft Substitutes market was the fastest growing market in the region.


Asia Pacific Dental Bone Graft Substitutes Market is expected to grow at the fastest CAGR from 2022 to 2030. An increase in medical tourism and government initiatives are two factors that have contributed to the growth of the market in this region. Additionally, the region's growing elderly population is raising the risk of dental issues is also aiding the market growth. Further, the China Dental Bone Graft Substitutes market held the largest market share, and the India Dental Bone Graft Substitutes market was the fastest growing market in the region.


Dental Bone Graft Substitutes Key Market Players & Competitive Insights


Major market players are investing in R&D to expand their product lines, which will fuel the growth of the Dental Bone Graft Substitutes market. Participants in the market are also undertaking various strategic initiatives to expand their footprint. Significant market developments include new product launches, mergers and acquisitions, contractual agreements, increased investments, and collaboration with other players.


One of the primary business strategies adopted by manufacturers in the Dental Bone Graft Substitutes industry is introducing new products in the market. In recent years, Dental Bone Graft Substitutes Industry has been adopted in many hospitals and healthcare institutes. The Dental Bone Graft Substitutes market major player such as Orthogen, LLC (US), LifeNet Health (US), Dentium (South Korea), Zimmer Biomet Dental (US), Medtronic Plc (Ireland), Institut Straumann AG (Switzerland), Dentsply Sirona (US), Geistlich Pharma AG (Switzerland), and Biohorizons Iph Inc. (US) are conducting research & development activities.


LifeNet Health is a pioneer in regenerative medicine and the most reputable provider of transplant solutions in the world, offering everything from organ procurement to bio-implants and cellular therapies. In October 2022, LifeNet Health displayed the most cutting-edge allograft biologics for fusion during that time in the North American Spine Society (NASS) 2022 Annual Meeting was held in Chicago from October 12–14.


Zimmer Biomet develops new methods to treat conditions that affect or injure the bones, joints, and supporting soft tissues. In March 2022, Biocomposites has entered into a multi-year agreement with Zimmer Biomet, for distributing genex Bone Graft Substitute with its new mixing system and delivery options in the U.S. orthopaedic market.


Key Companies in the Dental Bone Graft Substitutes market includes




  • Orthogen LLC (US)




  • LifeNet Health (US)




  • Dentium (South Korea)




  • Zimmer Biomet Dental (US)




  • Medtronic Plc (Ireland)




  • Institut Straumann AG (Switzerland)




  • Dentsply Sirona (US)




  • Geistlich Pharma AG (Switzerland)




  • Biohorizons Iph Inc. (US), among others




Dental Bone Graft Substitutes Industry Developments


March 2022:A pioneer in regenerative medicine polymer technology, Molecular Matrix, Inc. (MMI), announced the full release of its Osteo-P Synthetic Bone Graft Substitute (BGS) for use in the musculoskeletal system..


January 2019:Bioventus launched OSTEOMATRIX+, a new generation biphasic bone graft for use in bone remodelling in a range of orthopaedic and spine applications. A moldable alternative to bone grafts, OSTEOMATRIX+ is made of bovine collagen and biphasic hydroxyapatite/ß-tricalcium phosphate granules to create a stable, porous scaffold and maintain osteoconductivity throughout the bone remodelling process.


Dental Bone Graft Substitutes Market Segmentation


Dental Bone Graft Substitutes Type Outlook (USD Billion, 2018-2030)




  • Allograft




  • Xenograft




  • Alloplast




Dental Bone Graft Substitutes Application Outlook (USD Billion, 2018-2030)




  • Ridge Augmentation




  • Sinus Lift




  • Socket Preservation




  • Periodontal Defect




Dental Bone Graft Substitutes End-User Outlook (USD Billion, 2018-2030)




  • Dental Clinics




  • Hospitals




Dental Bone Graft Substitutes Regional Outlook (USD Billion, 2018-2030)




  • North America






  • US




  • Canada






  • Europe






  • Germany




  • France




  • UK




  • Italy




  • Spain




  • Rest of Europe






  • Asia-Pacific




    • China




    • Japan




    • India




    • Australia




    • South Korea




    • Australia




    • Rest of Asia-Pacific






  • Rest of the World




    • Middle East




    • Africa




    • Latin America





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