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Microcarriers Market Analysis

ID: MRFR//5446-HCR | 90 Pages | Author: Kinjoll Dey| May 2024

The microcarriers market dynamics are shaped by a myriad of factors influencing its growth trajectory and evolution. At its core, the demand for microcarriers is primarily driven by the expanding biopharmaceutical industry and the growing adoption of cell-based therapies. Microcarriers serve as a critical component in the production of biologics, vaccines, and cell therapies by providing a supportive environment for the growth and expansion of adherent cells. With the rising prevalence of chronic diseases and the increasing emphasis on personalized medicine, there is a growing need for efficient and scalable cell culture systems, driving the demand for microcarriers.

Additionally, advancements in bioprocessing technologies and the shift towards automated manufacturing processes are fueling market growth. Biopharmaceutical companies are increasingly investing in process optimization and automation to enhance productivity, reduce production costs, and ensure consistent product quality. Microcarriers play a crucial role in enabling scalable cell culture processes, allowing manufacturers to achieve higher cell densities and production yields while streamlining manufacturing workflows. As a result, there is a growing demand for innovative microcarrier products that offer enhanced performance, versatility, and ease of use.

Moreover, the market dynamics of microcarriers are influenced by regulatory frameworks, quality standards, and industry best practices. Regulatory compliance is a key consideration for biopharmaceutical manufacturers, as they are required to adhere to stringent guidelines and standards to ensure the safety, efficacy, and quality of their products. Microcarriers used in cell culture applications must meet regulatory requirements for biocompatibility, sterility, and purity, driving the demand for high-quality, cGMP-compliant products. Manufacturers that demonstrate compliance with regulatory standards and provide robust quality assurance systems are better positioned to capitalize on market opportunities and gain customer trust.

Furthermore, market dynamics are shaped by competitive forces, with numerous companies vying for market share through product differentiation, innovation, and strategic partnerships. Established players in the microcarriers market leverage their technical expertise, manufacturing capabilities, and global distribution networks to maintain a competitive edge. They invest in research and development to introduce novel microcarrier formulations, surface coatings, and functional modifications that enhance cell attachment, proliferation, and differentiation. Moreover, strategic collaborations between microcarrier manufacturers and biopharmaceutical companies enable joint product development, customization, and validation, fostering innovation and market expansion.

The evolution of cell therapy and regenerative medicine is also driving market dynamics, as these emerging therapeutic modalities hold immense promise for addressing unmet medical needs and revolutionizing disease treatment. Microcarriers play a crucial role in the scalable manufacturing of cell-based therapies, enabling the production of large quantities of therapeutic cells for clinical applications. With the growing interest and investment in cell therapy research and development, there is a corresponding increase in demand for microcarriers tailored to specific cell types, culture conditions, and therapeutic applications.

Despite the promising growth prospects, the microcarriers market faces certain challenges and uncertainties that may impact its trajectory. Market consolidation, pricing pressures, and supply chain disruptions pose challenges for smaller players and new entrants, limiting their ability to compete with larger, more established companies. Moreover, concerns regarding product quality, consistency, and scalability remain key considerations for biopharmaceutical manufacturers, driving the need for robust quality control measures and manufacturing processes.

Covered Aspects:

Report Attribute/Metric Details
Segment Outlook Product Type, Application, and End-User Geographies Covered North America, Europe, Asia-Pacific, and the Rest of the World (RoW) Key Vendors Sartorius AG, Merck KGaA, Danaher Corporation, Thermo Fisher Scientific, Inc., HiMedia Laboratories Pvt. Ltd., and Eppendorf SE Key Market Opportunities Rising monoclonal antibody production Key Market Drivers Rising demand for cell-based vaccines

Global Microcarriers Market Research (MRFR Insights)


The Microcarrier Market is anticipated to reach USD 1.57 Billion by 2032 at 5.6% CAGR during the forecast period 2023-2032. The market's growth is attributed to the high demand for cell-based vaccines & therapeutics, increasing incidence of various diseases & disorders like diabetes, cancer, rheumatoid arthritis, hemophilia, and others, huge investments for the development of innovative therapies, and consistent technological advancements in cell biology research. TheĀ  microcarriers market size is expected to reach approximately USD 1.18 Billion by 2027. Moreover, the rising demand for cell-based vaccines is the prominent driving factor for the market. Earlier vaccines were created in eggs and then harvested, which was a time and labor-intensive process.


COVID-19 Impact Analysis


There was a considerable decrease in patient visits during the pandemic due to the cancellation of medical procedures, especially elective procedures, to stop the spread of the COVID-19 pandemic. As per an Elsevier Public Health Emergency Collection report, more than 89% of the total lens utilizers were affected by the pandemic, and 72% reported less utilization than usual. Furthermore, according to the study by the College of Optometrists, 43% to 72% of wearers decreased contact lens utilization because of the reduced requirement for lenses due to the limited outdoor activities. Moreover, in 2020, Johnson and Johnson Vision Care, Inc. registered a decline of 11.7% in revenue.


Microcarriers Market Dynamics


The growth in the cell therapy industry and the huge demand for biopharmaceutical products are contributing to the growth of the microcarrier industry. As microcarriers are the matrices that help the growth of adherent cells, these small beads have found high utilization in stem cell therapy. The conceivable therapeutic actions from mesenchymal stem cells and pluripotent stem cells have enhanced the demand for stem cell therapy for treating infrequent diseases. As these stem cells are adherent, huge production of cell therapies needs an extensive amount of microcarrier consumables. Moreover, technological advances have permitted the development of vaccines in cell cultures resulting in a time-efficient and large production of vaccines, even offering better protection. As per CDC, the US FDA has approved Flucelvax Quadrivalent, a cell culture-based flu vaccine for adults 6 months and older. The growing incidence of infectious & chronic diseases, along with the current pandemic, is expected to drive the microcarrier's marketspace and result in strong growth during the forecasted period.


Market Drivers



  • Growing demand for cell-based vaccines


The enhancement in population, climate change, and increasing contact between humans and animals has increased the threat of new viruses. The growing incidence of infectious diseases and the increasing risk of pandemics are expected to drive vaccine demand worldwide. Cell culture is increasingly becoming a major part of vaccine production in the pharmaceutical industry. Vaccines were manufactured by increasing and harvesting viruses in chicken eggs, a time-consuming process. In this regard, cell-based vaccine production has become a far more efficient method owing to its shortened lead time and the capacity to produce vaccines in larger quantities according to demand.


Market Restraints:



  • The high price of cell biology research


Cell biology includes R&D on new therapies, including stem cell and gene therapies. The equipment, media, reagents, and other products related to research must be of the highest quality to deliver accurate results. Owing to the growing requirement to maintain high-quality standards (through high-grade products) and comply with guidelines set up by regulatory bodies, the cost of cell biology research has risen considerably. As a result, academic institutes and small-scale firms with limited budgets cannot afford to perform cell biology research. Since microcarriers discover applications in stem cell biology, this factor will likely hamper the market growth.


Market Opportunities:



  • Growing monoclonal antibody production


The demand for monoclonal antibodies is increasing ly due to the growing popularity of targeted treatment options for indications, including oncology and autoimmune & inflammatory disorders. As antibodies are administered in huge doses, the requirement for mAbs is equally high. Many current biologics in the pipeline target the indications, which are small-molecule-dominated and have a large patient pool. This represents that in the forecast period, the trend of biologics could enter several of the non-traditional biologic disease areas, which could benefit from the increased therapeutic efficacy.


Microcarriers MarketĀ Segmentation


Microcarriers Product Type Insights


TheĀ  microcarriers market segmentation, based on product type, is equipment {bioreactors, culture vessels, cell counters, filtration systems, and other equipment}, consumables {media [serum-based media, serum-free media, and other media], reagents, microcarrier beads {cationic microcarriers, collagen-coated microcarriers, protein-coated microcarriers, and other microcarrier beads}. TheĀ  microcarriers market growth was prominently high under the microcarrier beads category in 2021 due to increased cell biology research, increasing requirement for regenerative medicines and biopharmaceuticals, and the existence of several microcarrier beads that can be employed for different purposes attributed to the significant market growth.


Microcarriers Application Insights


TheĀ  microcarriers market segmentation, based on application, is vaccine manufacturing, cell therapy, biologics manufacturing, and other applications. In 2021, cell therapy accounted for the largest share of theĀ  market due to the increased adoption of microcarriers for cell therapy. However, vaccine manufacturing is to register the highest growth rate during the forecast period due to the growing demand for vaccines for various viruses.


Microcarriers End User Insights


Based on end user, theĀ  market is divided into pharmaceutical & biotechnology companies, research institutes, and contract research organizations. The pharmaceutical & biotechnology companies category dominated the market for microcarriers in 2021 due to the increasing incidence of cancer and growing cases of infectious diseases & genetic disorders, resulting in the growing demand for producing safe & effective medicines or treatments.


Global Microcarriers Market Share, by Region, 2021 (%)Microcarriers Market Share, by Region, 2021Microcarriers Market Overview, by Region Insights


By region, the Ā microcarriers market has been divided into North America, Europe, Asia-Pacific, and the Rest of the World. North America accounted for the most extensive market share. Asia-Pacific will exhibit the highest CAGR during the forecast period.


North America


North America dominated the market share in 2021. The growing cases of chronic and infectious diseases, enhanced awareness of personalized medicines, improved healthcare infrastructure and reimbursement models, existence of key market players, and intensive R&D activities have fueled the region's growth. Moreover, regulatory assistance for biopharmaceuticals and regenerative medicines is also driving the market entry of new cell-based therapies. For instance, the US FDA predicts by 2025. It'll be approving approximately 10 to 20 cell and gene therapy products each year owing to the current clinical success speeds and the product pipeline.


Asia-Pacific


Asia-Pacific accounted for the second-largest market share in the Ā market in 2021. The government inducements for vaccine production and low operation & labor charges drive multiple regional research settings. The Asia Pacific region is also driven by the high domestic demand for biologics and growing economies and has the highest senior population. Furthermore, several local Asian and international firms are developing several of the globe's new bioprocessing structures in this region. For instance, in October 2021, Singapore noticed the enhancement of Lonza's facility for mammalian services. The CDMO has added this capacity to assist growing manufacturing & analytical needs.


Microcarriers Market Competitive Landscape


The market includes tier-1, tier-2, and local market players. The tier-1 and tier-2 market players haveĀ  reach with diverse product portfolios. Companies such as Thermo Fisher Scientific, Inc., Sartorius AG, Merck KGaA, Danaher Corporation, HiMedia Laboratories Pvt. Ltd., and Eppendorf SE dominate theĀ  market due to product differentiation, financial stability, strategic developments, and diversified regional presence. The players are concentrating on supporting research and development. Furthermore, they embrace strategic growth initiatives, such as development, joint ventures, product introduction, and partnerships, to strengthen their market position and capture an extensive customer base.


Prominent players in theĀ  microcarriers market research include Corning Incorporated, VWR International LLC, Lonza Group Ltd, Merck KGaA, Bio-Rad Laboratories, Inc., and denovoMATRIX GmbH, among others.


Microcarriers Market Segmentation


Microcarriers Product Type Outlook



  • Equipment

    • Bioreactors

    • Culture Vessels

    • Cell Counters

    • Filtration Systems

    • Other Equipment



  • Consumables

    • Media

      • Serum-Based Media

      • Serum-Free Media

      • Other Media



    • Reagents

    • Microcarrier Beads

      • Cationic Microcarriers

      • Collagen-coated Microcarriers

      • Protein-coated Microcarriers

      • Other Microcarrier Beads






Microcarriers Application Outlook



  • Vaccine Manufacturing

  • Cell Therapy

  • Biologics Manufacturing

  • Other Applications


Microcarriers End User Outlook



  • Pharmaceutical & Biotechnology Companies

  • Research Institutes

  • Contract Research Organizations


Microcarriers Region Outlook



  • North America

    • US

    • Canada

    • Mexico



  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Rest of Europe



  • Asia-Pacific

    • China

    • India

    • Japan

    • Australia and New Zealand

    • Rest of Asia-Pacific



  • Rest of the World

    • South America

    • Middle East

    • Africa




Objectives of the Study


The objectives of the study are summarized in 5 stages. They are as mentioned below:


Microcarriers MarketĀ Forecast & Size:


To identify and estimate the market size for the Ā microcarriers market report segmented by product type, application, and end-user by value (in US dollars). Also, to understand the consumption/ demand created by consumers in theĀ  microcarriers market forecast between 2022 and 2030


Market Landscape and Trends:


To identify and infer the drivers, opportunities, restraints, and challenges in theĀ  microcarriers market growth


Market Influencing Factors:


To find out the factors which are impacting the Ā microcarriers market size among consumers


Impact of COVID-19:


To identify and understand the several factors involved in the market affected by the pandemic


Company Profiling:


To provide a detailed insight into the key companies operating in the market. The profiling will include the company's financial health in the past 2-3 years with segmental and regional revenue breakup, product offering, SWOT analysis, recent developments, and key strategies.


Intended Audience



  • Microcarriers producers

  • Raw material suppliers

  • Retailers, wholesalers, and distributors

  • Governments, associations, and industrial bodies

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