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Cholic acid Market Size

ID: MRFR//6619-CR | 70 Pages | Author: Rahul Gotadki| July 2019

The cholic acid market is influenced by various factors that drive its growth and dynamics. Firstly, the pharmaceutical industry's demand for cholic acid as a key raw material for the synthesis of bile acid-based drugs plays a significant role in market expansion. Cholic acid, a primary bile acid naturally produced in the liver, serves as a crucial starting material for the production of bile acid derivatives used in pharmaceutical formulations. As the pharmaceutical sector continues to develop new drugs for various therapeutic applications, the demand for cholic acid as a precursor remains robust.

Moreover, regulatory factors shape the cholic acid market landscape. Regulations governing the production, distribution, and use of cholic acid vary across different countries and regions. Compliance with regulatory standards is essential for manufacturers to ensure product quality, safety, and efficacy. Changes in regulations related to pharmaceutical ingredients or dietary supplements may impact the cholic acid market by influencing manufacturing practices, labeling requirements, and market access for suppliers.

Additionally, market competition drives innovation and influences pricing strategies within the cholic acid market. As the market becomes more competitive with the entry of new suppliers and the emergence of alternative production methods, manufacturers strive to differentiate their products through factors such as purity, quality, and pricing. Price competition may intensify as suppliers seek to gain market share by offering competitive pricing while maintaining product quality and reliability.

Furthermore, technological advancements in cholic acid production methods contribute to market growth and efficiency. Traditional methods of cholic acid extraction from animal bile have limitations in terms of scalability, cost, and environmental impact. However, advancements in biotechnology and chemical synthesis techniques enable the production of cholic acid through microbial fermentation or chemical synthesis from renewable resources. These innovative production methods offer advantages such as higher yields, lower production costs, and reduced environmental footprint, thereby driving market expansion.

Moreover, consumer trends and dietary preferences influence the demand for cholic acid in the food and dietary supplement industries. Cholic acid is used as a food additive in various products such as infant formula, nutritional supplements, and functional foods. Consumer awareness of the health benefits associated with bile acids, including their role in fat digestion and absorption, may drive demand for cholic acid-containing products. Additionally, dietary supplement manufacturers may incorporate cholic acid into formulations targeting digestive health or weight management, further stimulating market growth.

Furthermore, demographic factors such as population growth, aging demographics, and changing lifestyles impact market demand for cholic acid and related products. As the global population grows and ages, the prevalence of age-related conditions such as liver diseases, gallstones, and dyslipidemia increases, driving demand for pharmaceuticals and dietary supplements containing cholic acid. Changes in dietary habits and lifestyle choices, such as increased consumption of high-fat diets or sedentary lifestyles, may also contribute to the demand for cholic acid-based products targeting digestive health and metabolic disorders.

Lastly, economic factors such as GDP growth, healthcare expenditure, and purchasing power influence market dynamics and consumer spending on cholic acid products. Countries with rising healthcare expenditures and increasing disposable incomes may experience higher demand for pharmaceuticals and dietary supplements containing cholic acid. Conversely, economic downturns or fluctuations in currency exchange rates may impact market growth by affecting consumer purchasing power and healthcare budgets.

Covered Aspects:

Report Attribute/Metric Details
Growth Rate   7.4% (2023- 2032

Cholic Acid Market Overview


The Cholic acid Market is expected to grow USD 265 million at a CAGR 7.4% during the forecast pwriod 2023- 2032. Cholic acid structure made by the liver using cholesterol is termed cholic acid. The primary role of Cholic acid is to ensure that fat is broken down into smaller particles and subsequently bring about perfect digestion in the human body. Cholic acid is used in the production of ursodeoxycholic acid, a pharmaceutical agent used in the treatment of conditions like gall bladder stones and other liver diseases. With the use of cholic acid function in treating chronic diseases, it is indeed going to register a very high value in the global economy.


Significant factors influencing the market's growth include increased obesity, gallbladder cancer, increased geriatric population, and many more. On the other hand, strict regulations and policies tend to pull back the market growth significantly.


COVID-19 analysis


Life has taken a sharp turn with the onset of this deadly pandemic. Physical, mental, and financial disturbances are being observed in every sector. The business has been affected a lot too. With worldwide lockdown and the fear of Covid set in, the companies have been shut down for quite a lot. All this is not over yet but what needs to be understood is that everyone should learn to live with it. If nothing can be done with the virus, we can at least change the working pattern and style to ensure we are on the right track. The reports that have been prepared are accurate and to the point description of what the companies should do to combat the losses and take care of the future perspective. Apart from the qualitative and quantitative aspects, the current cholic acid market analysis is also included in the reports.


Market Dynamics


One of the significant factors behind the growth of the Cholic acid market is the increase in the cases of gallbladder cancer. And according to the studies, gallstones are the reason behind the development of the market. This study revealed that almost 2,20,00 new cases of people suffering from gallbladder cancer were diagnosed worldwide in the year 2018. This high rate of gall cancer cases can be correlated with gallstones too. Therefore, the growing rate of gallbladder cancer has ultimately led to an increase in the usage of colic acid. The entire scenario has made the market grow at a favorable rate. The market is expected to grow at a similar place due to changing lifestyles, obesity, and similar factors leading to liver diseases and gall bladder conditions.


Regulatory Implications


Few factors affect the cholic acid market analysis, but the one that has been affecting the most is the regulations and laws laid down by various regulatory bodies, governments, and local bodies for the wise usage of cholic acid. These are indeed strict and stringent and holds back the market from growing further. The regulations are implemented because of the use on the human body. Though they have been found very useful in treating liver and gallbladder conditions, there are still some contraindications that negatively affect the human body. The regulatory bodies need to make sure that colic acid is done in an appropriate manner and that it does not cause any harm to any human being or even the environment. No doubt the regulations are structured, but there is a fire need for such stringent rules to make cholic acid function be implemented in a wiser way.


Cholic Acid Market Share, by Region, 2018 (%)   Cholic Acid Market


Source: MRFR Analysis


Segmentation Overview


The market can be divided based on two factors. They are:


Based on application: Based on application, the market can further be subdivided into the following categories:



  • Emulsifier

  • Detergents

  • Medicines

  • Organic acid


Based on method: Based on the technique, the market can further be classified into the following subcategories:



  • Folding ethyl acetate separation method

  • Folding ethanol crystallization method

  • Folding animal extraction

  • Others


Based on these two broad classifications of the market, each of them has a unique market value. Based on the application, the Medicines segment holds a significant part in the cholic acid market. With its widespread use in various kidney diseases, it has gained popularity across the world.


Regional analysis


Based on the regions, the cholic acid market has the following subtypes:



  • Americas

  • Europe

  • The Middle East and Africa

  • Asia- Pacific


Europe holds the most significant share in the market with a value of almost 39.5% of the total stake.  The dominance of the region in the market is primarily due to substantial manufacturers in the area.


The Asia Pacific also holds a significant share of the ursodeoxycholic acid market. This is because of the increase in ten obese populations the countries like India and China. Obesity comes with an increased risk of gall stems and, after that, gallbladder cancer.


The cholic acid market expects to attend a CAGR of 8.47% during the forecast period. The American region has two central areas that include North America and Latin America. Increased gall bladder stones are likely to be a significant factor in the increased growth of the market.


The Middle East and Africa have the most negligible share in the cholic acid market but expect a steady increase due to the increased geriatric population in the region.


Competitive landscape


The major players are Alchem International Ltd (US), Zhejiang Yongning Pharmaceutical (Zhejiang), Showa Denko KK (Japan), Erregierre SpA (Italy), Retrophin, Inc. (the US), Fujimoto Chemicals (Japan), PharmaZell GmbH (Germany), Panjin Hengchanglong Pharmaceutical (China), Kinsy SL (Spain), Istituto Biologico Chemioterapico SpA (Italy), Daewoong Bio, Inc. (South Korea), Suzhou Tianlu Biopharmaceuticals Co. Ltd (China, Dipharma Francis SRL (Italy), New Zealand Pharmaceuticals Limited (New Zealand) and Industria Chimica Emiliana SRL (Italy).


All these significant players in the market have been working in a strategic and a planned manner. Various collaborations, acquisitions, and mergers amongst themselves have taken the call to the heights of success. They have also been leading the market as idols for the new entrants. It is not just for the growth of themself but also for the development of the market as a whole.


Recent advancements


Here are few recent advancements made in the cholic acid market:



  •     In April 2016, a significant stake created by the bile business was acquired by PharmaZell GmbH from Fayan international to expand its business horizons.

  •     New Zealand pharmaceutical limited was acquired by Archer’s capital in July 2016 to increase its share in the ursodeoxycholic acid market.

  •     Dipharma Francis SRL acquired Kalexsyn Inc. The motive was to offer services in the field of biotechnology and pharma.

  •     Advancements in the market are being made to ensure the market strictly follows the regulations laid down by the governments of various regions.

  •     The use of colic acid in industries like detergents and emulsifiers is being studied in depth. The main aim is to increase its usage in various end-use industries to increase the global market. 


Report overview


The report provided includes all the significant and small aspects required by an organization to do well and even combat losses during the Covid times. Starting from the overview of the cholic acid market to analysis based on the Covid impact, it also includes the market dynamics of the cholic acid market. The market segmentation based on method type and application is also included in the report. The market analysis based on five different regions is also provided with the report. The report's lap gives the details about the major players in the market and various strategies they have been following for the market's growth. The latest developments in the market are also provided to move forward with the newest technology. The current market scenario and the ways that can be implemented to bring about growth are shared in a detailed manner—all the reports are prepared by analysts with expertise in the field and the industry experts.

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