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Cholic acid Market Analysis

ID: MRFR//6619-CR | 70 Pages | Author: Rahul Gotadki| July 2019

The market dynamics of the cholic acid market are influenced by a variety of factors that shape supply, demand, pricing, and overall industry growth. Cholic acid, a bile acid naturally produced by the liver, is used in various applications, including pharmaceuticals, cosmetics, and research. Several key dynamics drive the performance of this market.

One of the primary drivers of the cholic acid market is the increasing demand from the pharmaceutical industry. Cholic acid is a key ingredient in the synthesis of pharmaceuticals, particularly in the production of bile acid-based drugs used to treat liver and gallbladder disorders, such as primary biliary cirrhosis and bile acid synthesis disorders. As the prevalence of these conditions rises and the pharmaceutical industry continues to innovate, the demand for cholic acid as a raw material for drug manufacturing grows, influencing market dynamics.

Regulatory factors significantly impact the cholic acid market dynamics. Stringent regulations govern the production, distribution, and use of cholic acid in pharmaceutical and cosmetic applications. Compliance with regulations set forth by regulatory bodies such as the Food and Drug Administration (FDA) in the United States and the European Medicines Agency (EMA) in Europe is essential for companies operating in the cholic acid market. Manufacturers must ensure product quality, purity, and safety to meet regulatory requirements and obtain approval for sale and distribution.

Technological advancements in cholic acid production methods contribute to market dynamics in the industry. Innovations in biotechnology, fermentation processes, and chemical synthesis techniques enhance the efficiency and scalability of cholic acid production, resulting in higher yields and lower production costs. Advanced production methods also enable manufacturers to produce cholic acid with greater purity and consistency, meeting the stringent quality standards required for pharmaceutical and cosmetic applications. These technological advancements drive market growth by expanding production capacity and improving product quality.

Market dynamics in the cholic acid industry are also influenced by competitive factors. The market is characterized by the presence of both established players and new entrants competing for market share. Competitive strategies such as product differentiation, pricing tactics, marketing campaigns, and distribution channels shape the competitive landscape and influence market dynamics. Established companies leverage their manufacturing capabilities, research and development expertise, and distribution networks to maintain a competitive edge, while new entrants may disrupt the market with innovative production techniques or strategic partnerships.

Economic factors, including healthcare expenditure, pharmaceutical R&D investment, and consumer purchasing power, impact market dynamics in the cholic acid industry. Economic downturns may lead to reduced spending on pharmaceuticals and cosmetics, affecting demand for cholic acid as a raw material. Conversely, economic growth and increased investment in healthcare and pharmaceutical innovation can stimulate market expansion as more companies develop bile acid-based drugs and cosmetic products containing cholic acid. Additionally, changing consumer preferences for natural and organic ingredients in cosmetics drive demand for cholic acid-based skincare products, further influencing market dynamics.

Globalization and international trade considerations also play a role in shaping market dynamics in the cholic acid industry. Manufacturers may seek to expand their presence in new markets with growing pharmaceutical and cosmetic industries. International trade agreements, tariffs, and trade barriers can impact market access and pricing strategies for cholic acid manufacturers operating across borders. Additionally, cultural differences, language barriers, and regulatory compliance requirements may pose challenges for companies seeking to enter new markets or expand their product offerings internationally.

Covered Aspects:

Report Attribute/Metric Details
Segment Outlook By Region

Cholic Acid Market Overview


The Cholic acid Market is expected to grow USD 265 million at a CAGR 7.4% during the forecast pwriod 2023- 2032. Cholic acid structure made by the liver using cholesterol is termed cholic acid. The primary role of Cholic acid is to ensure that fat is broken down into smaller particles and subsequently bring about perfect digestion in the human body. Cholic acid is used in the production of ursodeoxycholic acid, a pharmaceutical agent used in the treatment of conditions like gall bladder stones and other liver diseases. With the use of cholic acid function in treating chronic diseases, it is indeed going to register a very high value in the global economy.


Significant factors influencing the market's growth include increased obesity, gallbladder cancer, increased geriatric population, and many more. On the other hand, strict regulations and policies tend to pull back the market growth significantly.


COVID-19 analysis


Life has taken a sharp turn with the onset of this deadly pandemic. Physical, mental, and financial disturbances are being observed in every sector. The business has been affected a lot too. With worldwide lockdown and the fear of Covid set in, the companies have been shut down for quite a lot. All this is not over yet but what needs to be understood is that everyone should learn to live with it. If nothing can be done with the virus, we can at least change the working pattern and style to ensure we are on the right track. The reports that have been prepared are accurate and to the point description of what the companies should do to combat the losses and take care of the future perspective. Apart from the qualitative and quantitative aspects, the current cholic acid market analysis is also included in the reports.


Market Dynamics


One of the significant factors behind the growth of the Cholic acid market is the increase in the cases of gallbladder cancer. And according to the studies, gallstones are the reason behind the development of the market. This study revealed that almost 2,20,00 new cases of people suffering from gallbladder cancer were diagnosed worldwide in the year 2018. This high rate of gall cancer cases can be correlated with gallstones too. Therefore, the growing rate of gallbladder cancer has ultimately led to an increase in the usage of colic acid. The entire scenario has made the market grow at a favorable rate. The market is expected to grow at a similar place due to changing lifestyles, obesity, and similar factors leading to liver diseases and gall bladder conditions.


Regulatory Implications


Few factors affect the cholic acid market analysis, but the one that has been affecting the most is the regulations and laws laid down by various regulatory bodies, governments, and local bodies for the wise usage of cholic acid. These are indeed strict and stringent and holds back the market from growing further. The regulations are implemented because of the use on the human body. Though they have been found very useful in treating liver and gallbladder conditions, there are still some contraindications that negatively affect the human body. The regulatory bodies need to make sure that colic acid is done in an appropriate manner and that it does not cause any harm to any human being or even the environment. No doubt the regulations are structured, but there is a fire need for such stringent rules to make cholic acid function be implemented in a wiser way.


Cholic Acid Market Share, by Region, 2018 (%)   Cholic Acid Market


Source: MRFR Analysis


Segmentation Overview


The market can be divided based on two factors. They are:


Based on application: Based on application, the market can further be subdivided into the following categories:



  • Emulsifier

  • Detergents

  • Medicines

  • Organic acid


Based on method: Based on the technique, the market can further be classified into the following subcategories:



  • Folding ethyl acetate separation method

  • Folding ethanol crystallization method

  • Folding animal extraction

  • Others


Based on these two broad classifications of the market, each of them has a unique market value. Based on the application, the Medicines segment holds a significant part in the cholic acid market. With its widespread use in various kidney diseases, it has gained popularity across the world.


Regional analysis


Based on the regions, the cholic acid market has the following subtypes:



  • Americas

  • Europe

  • The Middle East and Africa

  • Asia- Pacific


Europe holds the most significant share in the market with a value of almost 39.5% of the total stake.  The dominance of the region in the market is primarily due to substantial manufacturers in the area.


The Asia Pacific also holds a significant share of the ursodeoxycholic acid market. This is because of the increase in ten obese populations the countries like India and China. Obesity comes with an increased risk of gall stems and, after that, gallbladder cancer.


The cholic acid market expects to attend a CAGR of 8.47% during the forecast period. The American region has two central areas that include North America and Latin America. Increased gall bladder stones are likely to be a significant factor in the increased growth of the market.


The Middle East and Africa have the most negligible share in the cholic acid market but expect a steady increase due to the increased geriatric population in the region.


Competitive landscape


The major players are Alchem International Ltd (US), Zhejiang Yongning Pharmaceutical (Zhejiang), Showa Denko KK (Japan), Erregierre SpA (Italy), Retrophin, Inc. (the US), Fujimoto Chemicals (Japan), PharmaZell GmbH (Germany), Panjin Hengchanglong Pharmaceutical (China), Kinsy SL (Spain), Istituto Biologico Chemioterapico SpA (Italy), Daewoong Bio, Inc. (South Korea), Suzhou Tianlu Biopharmaceuticals Co. Ltd (China, Dipharma Francis SRL (Italy), New Zealand Pharmaceuticals Limited (New Zealand) and Industria Chimica Emiliana SRL (Italy).


All these significant players in the market have been working in a strategic and a planned manner. Various collaborations, acquisitions, and mergers amongst themselves have taken the call to the heights of success. They have also been leading the market as idols for the new entrants. It is not just for the growth of themself but also for the development of the market as a whole.


Recent advancements


Here are few recent advancements made in the cholic acid market:



  •     In April 2016, a significant stake created by the bile business was acquired by PharmaZell GmbH from Fayan international to expand its business horizons.

  •     New Zealand pharmaceutical limited was acquired by Archer’s capital in July 2016 to increase its share in the ursodeoxycholic acid market.

  •     Dipharma Francis SRL acquired Kalexsyn Inc. The motive was to offer services in the field of biotechnology and pharma.

  •     Advancements in the market are being made to ensure the market strictly follows the regulations laid down by the governments of various regions.

  •     The use of colic acid in industries like detergents and emulsifiers is being studied in depth. The main aim is to increase its usage in various end-use industries to increase the global market. 


Report overview


The report provided includes all the significant and small aspects required by an organization to do well and even combat losses during the Covid times. Starting from the overview of the cholic acid market to analysis based on the Covid impact, it also includes the market dynamics of the cholic acid market. The market segmentation based on method type and application is also included in the report. The market analysis based on five different regions is also provided with the report. The report's lap gives the details about the major players in the market and various strategies they have been following for the market's growth. The latest developments in the market are also provided to move forward with the newest technology. The current market scenario and the ways that can be implemented to bring about growth are shared in a detailed manner—all the reports are prepared by analysts with expertise in the field and the industry experts.

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