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Huntington’s Disease Treatment Market Size

ID: MRFR//5466-HCR | 90 Pages | Author: Rahul Gotadki| May 2024

The size of Huntington’s Disease Treatment Market is anticipated to reach USD 2.9 Billion by 2027 at a CAGR of 17.7% over the forecast period 2023-2032. The growth and dynamics of the market for Huntington's disease treatment are determined by a range of factors.
In this context, one key driver is the fact that Huntington's disease, an inherited and rare neurodegenerative disorder characterized by gradual loss of ability to walk or speak coupled with dementia symptoms is common in people who are affected by it. As medical science has not yet found any cure for Huntington’s Disease, there is now increasing demand for therapeutic interventions that will reduce symptoms and improve the quality of life for sufferers from this tragic affliction including symptomatic management, physiotherapy, palliative care as well as research medications aimed at various aspects of the complex pathophysiology involved with this syndrome.
Technological advancements play a pivotal role in shaping the disease treatment market for Huntington's disease. Innovations in neuroscience research, gene therapy and neuroprotection have enabled the development of more targeted disease-modifying therapies. Furthermore, advanced molecular and genetic technologies have yielded valuable insights into the genetic basis underpinning this illness paving the way for personalized medicine approaches based on a patient's own biology.
Regulatory considerations are crucial in influencing the market dynamics of Huntington's disease treatments. This includes strict regulations and approvals being necessary to ensure safety and efficacy of such treatments by manufacturers. In addition to establishing credibility for huntington's therapeutics only compliance with regulatory requirements also instills confidence among doctors as well as patients fueling market growth thereof.
They affect economic factors such as health care spending levels and funding available for orphan diseases when considering integrating modern methods such as those used to treat HD into normal medical practices such as reimbursement policies or coverage affecting their financial feasibility The availability & affordability of these drugs depends on economic considerations relating either directly (as seen e.g. in the case of the US) or indirectly (due to unique local circumstances such as infrastructure limitations) to their accessibility by patients as well as take-up among health professionals that is still low because of high cost and other challenges associated with orphan disease management mainly in developing countries.
This has led to market fragmentation across different regions where various barriers need to be surmounted in managing Huntington’s disease. Here, prevalence levels for HD, demographics and health care delivery systems differ from one country or region which have a bearing on what types of treatment are needed most urgently. In order to meet the needs of specific markets, manufacturers often design strategies that help them navigate through regulatory requirements applicable to each market.
Competitive dynamics play a role in fostering innovation and market expansion in the Huntington's disease treatment segment. Key pharmaceutical companies, academic research institutions, and advocacy groups drive drug development and commercialization strategies. Collaboration between these parties stimulates new forms of care, improved therapeutic approaches, better drug formulations thus making it possible for healthcare providers who treat Huntington’s Disease an array choices at their disposal.

Subsequently, continuous improvement of technology due to research and development activities supports market evolution in Huntington’s disease treatment space. This is reflected by ongoing attempts at finding agents capable of changing the course of HD while also improving its symptomatology through better therapies including targets for novel treatments offered by this industry sector today. Research-driven innovations help create solutions that are more responsive both to emerging trends among healthcare providers involved primarily with treating HD but also adapt over time based specifically upon evolving patients’ expectations concerning more effective handling options available within their reach.

Covered Aspects:

Report Attribute/Metric Details
Growth Rate   17.7% (2023-2032

Huntington’s Disease Treatment Market Overview


Huntington’s Disease Treatment Market is expected to reach USD 2.9 Billion rise steadily at a CAGR of 17.7% during forecast period of 2023-2032.This rise is due to high RandD speculations for new product improvement, research collaboration, and the high HD burden in European countries. Huntington’s disease is an infrequent inherited neurodegenerative disease that affects various generations. The impact of this disease is high when the age is between 30 and 50, hampering their ability to work, care for families, and eventually complete daily tasks. The generality differs by more than ten-fold between geographical areas, which can be associated with differences in case ascertainments and diagnostic criteria. As a result, the generality of enlarged replications in the general population may be larger than expected. The Asian population has continuously had a lower generality, while Europe, North America, and Australia have a higher generality.

Segmentation:


Huntington’s Disease Treatment Market is segmented into drug type, treatment and end-users. On basis of drug type the Huntington’s Disease Treatment Market is segmented into tetrabenazine, deutetrabenazine, selective serotonin reuptake inhibitor (SSRI), chlorpromazine,haloperidol, risperidone, olanzapine, clozapine another drug type.Based on treatment the market is further segmented into two types such as symptomatic therapy and disease-modifying therapy.On basis of end-users the market is further segmented into hospital, clinics, retail pharmacies, online pharmacies and others.


The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Huntington’s Disease Treatment Market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada. US account for the largest share of traumatic brain injury market.  The European Huntington’s Disease Treatment Market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. 


The Huntington’s Disease Treatment Market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The huntington’s disease treatment market in the Middle East & Africa has been segmented into the Middle East and Africa.


Key players:


Some of the key players in the Huntington’s Disease Treatment Market are Alnylam Pharmaceuticals Inc., AmpliPhi Biosciences Corp, Ceregene Inc., Lundbeck, Prana Biotechnology Limited, Teva Pharmaceutical Industries Ltd., Cortex Pharmaceuticals Inc., Vertex Pharmaceuticals Incorporated, Auspex Pharmaceuticals, SOM Biotech, GlaxoSmithKline, Siena Biotech, Raptor Pharmaceutical, Pfizer, Palobiofarma, Omeros Ipsen, Valeant Pharmaceuticals International Inc.


Regional Market Summary


Global Huntington’s Disease Treatment Market Share (%), by Region, 2017 Huntington’s Disease Treatment Market Share


Source: Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), American association of neurological surgeon


Geographically, the America holds the highest market share for huntington’s disease treatment market and the reason being many market players are engaged in development of new drug product innovation. According to the survey carried out by one of the University of Sheffield, the estimated prevalence of huntington’s disease in North America, North Western Europe and Australia ranges from 5.96 to 13.7 cases per 100 000 population.


Europe is expected to be the second largest market in the globe owing to the increasing aging population, increasing prevalence of targeted population, focus on aesthetic appearance, increasing research base. Whereas rise in susceptible immune compromised patient population is responsible for market growth in this region. 


The prevalence of huntington’s disease is significantly lower in Asian populations compared to Western Europe, North America and Australia.


The market in the Middle East & Africa is likely to account for the smallest share of the global huntington’s disease treatment.


Huntington’s Disease Treatment Market by Drug Type:



  •      Tetrabenazine

  •      Deutetrabenazine

  •      Selective Serotonin Reuptake Inhibitor (SSRI)

  •      Chlorpromazine

  •      Haloperidol

  •      Risperidone

  •      Olanzapine

  •      Clozapine

  •      Other


Huntington’s Disease Treatment Market, by Treatment:



  •      Symptomatic Therapy

  •      Disease-Modifying Therapy


Huntington’s Disease Treatment Market, by End-Users:



  •       Hospital

  •       Clinics

  •       Online Pharmacies

  •       Retail Pharmacies

  •       Others


Huntington’s Disease Treatment Market, by Region:



  • Americas

    •  North America

      •     US

      •     Canada



    •  South America



  • Europe

    •  Western Europe

      •   Germany

      •     France

      •   Italy

      •   Spain

      •   UK

      •   Rest of Western Europe



    •  Eastern Europe



  • Asia Pacific

    •   Japan

    •   China

    •  India

    • Australia  

    • Republic of Korea 

    • Rest of Asia Pacific 



  • The Middle East & Africa

    •   Middle East

    •   Africa




Huntington’s Disease Treatment Market Key Players:



  •        Alnylam Pharmaceuticals Inc

  •        AmpliPhi Biosciences Corp

  •        Ceregene Inc

  •        Lundbeck

  •        Prana Biotechnology Limited

  •        Teva Pharmaceutical Industries Ltd

  •        Cortex Pharmaceuticals Inc

  •        Vertex Pharmaceuticals Incorporated

  •        Auspex Pharmaceuticals

  •        SOM Biotech

  •        GlaxoSmithKline

  •        Siena Biotech

  •        Raptor Pharmaceutical

  •        Pfizer

  •        Palobiofarma

  •        Omeros

  •        Ipsen

  •        Valeant Pharmaceuticals International Inc


Recent Development


The major players, such as Neurocrine Bioscience, Inc. and Azevan Pharmaceuticals, Inc. are concentrating on research and improvement of symptomatic therapies for HD. Azevan Pharmaceuticals is developing SRX246 as an innovative drug to treat neuropsychiatric symptoms in Huntington's disease. SRX246 is a medicine that does its work by blocking vasopressin 1 a receptor in the brain. However, presently approved medicines give symptomatic and palliative care and do not target the fundamental cause of the disease. In addition, medications can reduce the seriousness of symptoms, they are often connected with unfavorable effects such as somnolence, gait issues, dysphagia, and apathy, which can have adverse impacts on a patient’s quality of life. Given the inefficiency of a cure for the disease, it is censorious to evaluate how health-related quality of life is affected in these patients.Intended Audience:



  • Manufacturers and Suppliers

  • Hospitals and Clinics

  • Laboratories and Associations

  • Research and Development (R&D) Companies

  • Government research institutes

  • Academic institutes and universities

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