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US Necrotizing Enterocolitis Market Research Report By End-User (Hospitals, Surgical and Ablation Centers, Research Institute, Others), By Treatment (Total Parenteral Nutrition (TPN), Gastrointestinal Decompression, Antimicrobial Therapy, Antifungal Treatment, Paracentesis, Others), and By Distribution (Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy, Others)-Forecast to 2035


ID: MRFR/HC/53276-HCR | 200 Pages | Author: Rahul Gotadki| June 2025

US Necrotizing Enterocolitis Market Overview


As per MRFR analysis, the US Necrotizing Enterocolitis Market Size was estimated at 1.08 (USD Billion) in 2023. The US Necrotizing Enterocolitis Market is expected to grow from 1.2 (USD Billion) in 2024 to 2.3 (USD Billion) by 2035. The US Necrotizing Enterocolitis Market CAGR (growth rate) is expected to be around 6.093% during the forecast period (2025 - 2035).


Key US Necrotizing Enterocolitis Market Trends Highlighted


Healthcare advancements and growing awareness of neonatal health are driving major developments in the US necrotizing enterocolitis (NEC) market. The rising number of premature deliveries in the US, which increases the frequency of disorders like NEC in neonates, is one of the main factors propelling the market.


Better outcomes for afflicted newborns are being supported by improved diagnosis and management techniques brought about by healthcare professionals' increased awareness of NEC.


Better clinical practices focused on early detection and intervention are being brought about by increased cooperation between hospitals and pediatric healthcare providers. This is crucial for lowering the morbidity linked to NEC.


The focus on research and development for novel treatment alternatives is another noteworthy trend. In order to prevent and manage NEC, there is a trend toward the development of novel therapeutics, such as pharmaceutical treatments and dietary changes.


Clinical trials and educational programs aimed against NEC are increasing, indicating a dedication by healthcare organizations to investigate novel treatment approaches.


The creation of preventative measures that include community health initiatives and parental education that emphasize breastfeeding, which has been proven to be effective in lowering the risk of NEC, is one opportunity to seize in the US market.


Furthermore, using cutting-edge medical technology, like telemedicine, to continuously monitor at-risk newborns can increase patient care and management strategies' effectiveness.


The US NEC market is poised for expansion, propelled by innovation and a cooperative approach among stakeholders committed to tackling this pressing health concern, with a particular emphasis on enhancing newborn healthcare outcomes.


US Necrotizing Enterocolitis Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


US Necrotizing Enterocolitis Market Drivers


Increasing Incidence of Necrotizing Enterocolitis


The rising incidence of Necrotizing Enterocolitis (NEC) among preterm infants is a significant driver for the US Necrotizing Enterocolitis Market. According to the Centers for Disease Control and Prevention (CDC), approximately 1 in 10 babies are born preterm in the United States, and those infants have a higher risk of developing NEC.


As preterm birth rates continue to increase, driven in part by factors such as advanced maternal age and multiple births, hospitals and healthcare providers are increasingly compelled to invest in research, treatment options, and innovative solutions to prevent and manage NEC.


Furthermore, the American Academy of Pediatrics emphasizes that with better neonatal care practices and improved survival rates of preterm infants, there is an anticipated increase in the overall number of NEC cases. This concerning trend creates a pressing demand for effective therapeutic strategies and underscores the growth potential within the US Necrotizing Enterocolitis Market.


Advancements in Treatment Protocols


Recent advancements in treatment protocols for Necrotizing Enterocolitis present a notable opportunity for growth within the US Necrotizing Enterocolitis Market. Innovations in surgical techniques, such as minimally invasive surgery, have shown promise in improving patient outcomes and reducing recovery times.


Furthermore, ongoing Research and Development efforts by organizations like the National Institutes of Health (NIH) and private sector companies are fueling the development of new pharmaceuticals and biologicals aimed specifically at NEC.


With increased funding and attention directed towards NEC treatment, it is projected that a more comprehensive array of treatment options will become available in the coming years, catering to the rising demand in the US and ultimately propelling market growth.


Growing Focus on Neonatal Health Initiatives


The growing focus on neonatal health initiatives in the United States is a key market driver for the US Necrotizing Enterocolitis Market. Health organizations such as the March of Dimes and the CDC are prioritizing neonatal care, which includes improving outcomes for preterm infants at risk for NEC.


Legislative measures like the Newborn Screening Saves Lives Act have emphasized the importance of early detection and intervention for serious conditions, including NEC.


As resources and funding are increasingly funneled into neonatal health programs, hospitals are more likely to adopt new diagnostic tools and treatment methods, further stimulating growth in the NEC market segment. This emphasis on enhancing neonatal care and reducing infant mortality rates is expected to drive demand for NEC-specific therapies in the coming years.


US Necrotizing Enterocolitis Market Segment Insights


Necrotizing Enterocolitis Market End-User Insights


The End-User segment of the US Necrotizing Enterocolitis Market represents a crucial aspect of the overall healthcare landscape, particularly as it pertains to treating this severe gastrointestinal condition predominantly affecting premature infants.


Hospitals generally account for a significant portion of this segment, as they provide comprehensive care facilities that encompass diagnostic, therapeutic, and surgical interventions. The presence of specialized neonatal units within hospitals facilitates immediate and effective management of necrotizing enterocolitis, making hospitals an indispensable component of the care continuum.


Surgical and Ablation Centers also play a critical role, offering targeted procedural interventions for patients suffering from advanced forms of necrotizing enterocolitis. The surgical management of this condition can be complex and often involves collaboration between pediatric surgeons and neonatologists to ensure optimal outcomes.


These centers specialize in performing intricate operations designed to remove necrotic bowel segments, thus contributing to improved patient recovery rates and long-term health. Research Institutes are increasingly becoming vital within this market, as they focus on advancing the understanding of necrotizing enterocolitis through clinical trials and innovative research.


This segment is dedicated to exploring novel therapeutic approaches, enhancing diagnostic tools, and ultimately contributing to the body of knowledge necessary for better management practices. Ongoing studies in Research Institutes are critical for identifying potential risk factors and understanding the pathophysiology of the condition, which may lead to breakthroughs in prevention and treatment.


In addition to these prominent categories, the "Others" segment encompasses a variety of non-traditional care settings that might include outpatient clinics, home care services, and educational organizations focused on necrotizing enterocolitis awareness.


These entities contribute to the broader healthcare ecosystem by providing support services, follow-up care, and educational outreach to families coping with the implications of this condition. This segment provides alternative avenues for treatment and recovery, thereby ensuring that families have access to the most suitable care options.


As the US healthcare system continues to evolve, various factors such as technological advancements, increasing awareness of early intervention, and an emphasis on specialized care are driving the growth of the End-User segment within the US Necrotizing Enterocolitis Market.


The interplay between these various segments highlights the importance of a multidisciplinary approach to care, ensuring that patients receive comprehensive treatment tailored to their unique needs.


As organizations and healthcare facilities collaborate more closely, the integration of services across hospitals, surgical centers, research institutions, and other healthcare setups will provide better outcomes for infants affected by necrotizing enterocolitis, ultimately benefiting the overall US healthcare landscape.


Necrotizing Enterocolitis Market End-User Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Necrotizing Enterocolitis Market Treatment Insights


The Treatment segment of the US Necrotizing Enterocolitis Market plays a crucial role in managing this serious condition predominantly affecting premature infants. With increased awareness and improved diagnostic techniques, the market has evolved to incorporate various methods, such as Total Parenteral Nutrition, which is vital for providing nutrition to infants with compromised gastrointestinal function.


Gastrointestinal Decompression is also significant as it helps relieve distension and restores functional bowel viability. Antimicrobial Therapy is essential in combating infections, while Antifungal Treatment addresses the prevalent risks posed by fungal pathogens in these vulnerable patients.


Paracentesis serves as a helpful intervention for managing fluid accumulation, contributing to patient comfort and recovery. Market growth is driven by rising incidences of necrotizing enterocolitis, alongside advancements in treatment technologies and protocols, enhancing survival rates.


Despite challenges, such as varying regional healthcare access and treatment costs, the overall outlook for the Treatment segment remains positive, thanks to ongoing Research and Development initiatives aimed at improving patient outcomes.


As a result, key treatment methods continue to dominate discussions in the medical community, fostering further innovation within the US Necrotizing Enterocolitis Market.


Necrotizing Enterocolitis Market Distribution Insights


The Distribution segment of the US Necrotizing Enterocolitis Market plays a crucial role in ensuring accessibility and availability of therapeutic products to healthcare providers and patients. The segment encompasses various channels including Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy, and others, each contributing uniquely to the market dynamics.


Hospital Pharmacies are essential as they facilitate immediate access to medications for inpatients, reflecting the urgency and critical care required for necrotizing enterocolitis cases. On the other hand, Online Pharmacies are gaining prominence due to the increasing trend of telemedicine and digital health solutions, offering convenience and efficient service for patients seeking medications.


Retail Pharmacies also maintain significant market influence, providing direct access to caregivers and families, thus enhancing patient adherence to treatment. Meanwhile, Direct Tender arrangements are vital for securing bulk purchases and ensuring that essential drugs reach hospitals and clinics effectively.


Each of these distribution channels not only caters to the diverse needs of healthcare providers but also addresses the varied accessibility requirements of patients across the United States, driving overall growth and efficiency in the US Necrotizing Enterocolitis Market.


Increasing awareness about the condition and the rising incidence rates are expected to further propel the importance of these distribution avenues in the upcoming years.


US Necrotizing Enterocolitis Market Key Players and Competitive Insights


The competitive insights of the US Necrotizing Enterocolitis Market reveal a dynamic landscape characterized by diverse stakeholders who are striving to enhance patient care and treatment outcomes. This segment primarily focuses on addressing the medical needs surrounding necrotizing enterocolitis, a serious intestinal condition primarily affecting premature infants.


The market is driven by increasing awareness of the condition, advancements in medical technology, and the growing demand for innovative treatment solutions. Stakeholders in the market include various players from pharmaceutical companies to medical device manufacturers, each vying for a significant foothold in this specialized arena.


The essence of competition revolves around the development of effective therapies, improving diagnostic methods, and establishing strategic partnerships to expand market reach and improve patient outcomes.


In the context of the US Necrotizing Enterocolitis Market, Hollister has established a strong presence marked by its commitment to innovative product development and patient-centered solutions. The company's expertise in medical devices and ostomy care has allowed it to cater to the specific needs of this niche market effectively.


Hollister's strengths lie in its robust research and development pipeline, which enables it to deliver high-quality products tailored for neonatal care. Additionally, the company benefits from a reputation for reliability and clinical efficacy, making its offerings preferred among healthcare professionals dealing with necrotizing enterocolitis.


Through educational initiatives and clinical partnerships, Hollister aims to educate healthcare providers and caregivers about optimal care practices, further solidifying its position in the market.


Medtronic, a prominent player in the US medical technology landscape, boasts a comprehensive portfolio of products and services pertinent to the Necrotizing Enterocolitis Market. The company is well-regarded for its extensive range of medical devices that enhance surgical procedures and patient monitoring in neonatal care.


Medtronic's strengths are underscored by its continuous investment in research and development, which leads to pioneering solutions aimed at improving surgical outcomes for infants suffering from this condition. The company's presence in the market is bolstered by strategic mergers and acquisitions that expand its capabilities and product offerings.


Medtronic has formed collaborative relationships with healthcare institutions to facilitate clinical studies, reinforcing its role as a leader in this domain. Their combination of advanced technology, experience, and commitment to improving care pathways for vulnerable patients position Medtronic as a crucial competitor in the US Necrotizing Enterocolitis Market.


Key Companies in the US Necrotizing Enterocolitis Market Include



  • Hollister

  • Medtronic

  • Acelity

  • Purdue Pharma

  • Danone

  • Baxter

  • Chiesi Farmaceutici

  • Janssen Pharmaceuticals

  • MediTouch

  • PediaMed Pharmaceuticals

  • Nestle

  • AbbVie

  • Elekta

  • Jude Medical

  • Sakraida Medical


US Necrotizing Enterocolitis Market Developments


Recent developments in the US Necrotizing Enterocolitis Market focus on the increasing awareness and prevalence of this serious gastrointestinal condition affecting premature infants. Companies such as Medtronic and Baxter are innovating with advanced medical devices and therapies aimed at early diagnosis and treatment.


In terms of market valuation growth, investments in R&D by firms like Acelity and AbbVie have led to advancements in cell and gene therapies, contributing to a more favorable treatment landscape.


The market also saw significant activity in mergers and acquisitions; for instance, in July 2023, Hollister made headlines with its acquisition of a smaller firm focused on innovative neonatal care solutions, aiming to enhance its product portfolio.


Another notable event occurred in August 2023 when Danone announced its strategic partnership with a biotech firm to develop a new nutritional formula specifically targeting neonates at risk of Necrotizing Enterocolitis.


These trends reflect a concerted effort across major healthcare players to address a critical need within neonatal care while leveraging the latest technologies and therapies to improve outcomes for vulnerable patients.


Necrotizing Enterocolitis Market Segmentation Insights



  • Necrotizing Enterocolitis Market End-User Outlook

    • Hospitals

    • Surgical and Ablation Centers

    • Research Institute

    • Others





  • Necrotizing Enterocolitis Market Treatment Outlook

    • Total Parenteral Nutrition (TPN)

    • Gastrointestinal Decompression

    • Antimicrobial Therapy

    • Antifungal Treatment

    • Paracentesis

    • Others





  • Necrotizing Enterocolitis Market Distribution Outlook

    • Direct Tender

    • Hospital Pharmacy

    • Retail Pharmacy

    • Online Pharmacy

    • Others



Report Attribute/Metric Details
Market Size 2023 1.08(USD Billion)
Market Size 2024 1.2(USD Billion)
Market Size 2035 2.3(USD Billion)
Compound Annual Growth Rate (CAGR) 6.093% (2025 - 2035)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Billion
Key Companies Profiled Hollister, Medtronic, Acelity, Purdue Pharma, Danone, Baxter, Chiesi Farmaceutici, Janssen Pharmaceuticals, MediTouch, PediaMed Pharmaceuticals, Nestle, AbbVie, Elekta, St. Jude Medical, Sakraida Medical
Segments Covered End-User, Treatment, Distribution
Key Market Opportunities Rising neonatal population demand, Advancements in diagnostic technologies, Increased awareness of disease risks, Growth in telehealth services, Enhanced parental support programs
Key Market Dynamics Rising neonatal population, Increased awareness and diagnosis, Advances in treatment options, Growing demand for probiotics, Emergence of telemedicine solutions
Countries Covered US


Frequently Asked Questions (FAQ) :

The US Necrotizing Enterocolitis Market was valued 1.2 billion USD in 2024.

By 2035, the market is projected to reach about 2.3 billion USD.

The market is anticipated to grow at a compound annual growth rate of 6.093% during the period from 2025 to 2035.

The hospital segment is projected to dominate the market, valued at 0.576 billion USD in 2024 and expected to reach 1.104 billion USD by 2035.

Major players in the market include Hollister, Medtronic, Acelity, Purdue Pharma, and Danone among others.

The market is segmented into hospitals, surgical and ablation centers, research institutes, and others.

The market value for surgical and ablation centers was 0.276 billion USD in 2024.

Emerging trends and increasing prevalence of necrotizing enterocolitis offer significant growth opportunities for the market.

By 2035, the market value for research institutes is expected to reach 0.416 billion USD.

Challenges such as regulatory hurdles and competition from alternative treatments may impact market growth.

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