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US Gamma Knife Market

ID: MRFR/HC/51019-HCR
200 Pages
Rahul Gotadki
October 2025

US Gamma Knife Market Research Report: Size, Share, Trend Analysis By Disease Indication (Brain Metastasis, Cancer, Arteriovenous Malformation, Trigeminal Neuralgia, Others) and By Anatomy (Head, Neck, Others) - Growth Outlook & Industry Forecast 2025 To 2035

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US Gamma Knife Market Infographic
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US Gamma Knife Market Summary

As per Market Research Future analysis, the US gamma knife market Size was estimated at 140.0 USD Million in 2024. The US gamma knife market is projected to grow from 147.57 USD Million in 2025 to 250.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 5.4% during the forecast period 2025 - 2035

Key Market Trends & Highlights

The US gamma knife market is poised for growth driven by technological advancements and increasing demand for non-invasive treatments.

  • Technological advancements in radiation therapy are enhancing treatment efficacy and patient outcomes.
  • The demand for non-invasive treatments is rising, particularly in the neurosurgery segment, which is the largest in the market.
  • Regulatory changes are fostering a quality-focused environment, thereby encouraging innovation and compliance.
  • The rising incidence of brain disorders and supportive reimbursement policies are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 140.0 (USD Million)
2035 Market Size 250.0 (USD Million)
CAGR (2025 - 2035) 5.41%

Major Players

Elekta AB (SE), Accuray Incorporated (US), Varian Medical Systems (US), Brainlab AG (DE), MediTech (US), Nicolet Biomedical (US), Shenzhen Huikang Medical (CN), Stereotactic Radiosurgery (US)

US Gamma Knife Market Trends

The gamma knife market is currently experiencing notable advancements, driven by technological innovations and an increasing prevalence of neurological disorders. The introduction of more precise and efficient gamma knife systems has enhanced treatment outcomes, making them more appealing to healthcare providers. Additionally, the growing awareness of non-invasive treatment options among patients is likely contributing to the rising demand for these systems. As healthcare facilities continue to invest in advanced technologies, the gamma knife market appears poised for sustained growth in the coming years. Moreover, the regulatory environment surrounding medical devices is evolving, which may impact the gamma knife market. Regulatory bodies are increasingly focusing on ensuring safety and efficacy, which could lead to more stringent approval processes. This shift may encourage manufacturers to prioritize quality and innovation in their product offerings. Furthermore, collaborations between technology firms and healthcare providers are likely to foster the development of next-generation gamma knife systems, potentially reshaping the competitive landscape. Overall, the gamma knife market seems to be on a trajectory of growth, influenced by technological advancements and changing healthcare dynamics.

Technological Advancements

Recent innovations in gamma knife technology are enhancing treatment precision and patient outcomes. Newer models incorporate advanced imaging techniques, allowing for better targeting of tumors and lesions. This trend is likely to attract more healthcare facilities to adopt gamma knife systems, as they seek to improve treatment efficacy.

Increasing Demand for Non-Invasive Treatments

There is a growing preference among patients for non-invasive treatment options, which is driving the gamma knife market. As awareness of the benefits of such procedures rises, more patients are opting for gamma knife treatments over traditional surgical methods, potentially leading to increased market growth.

Regulatory Changes and Quality Focus

The evolving regulatory landscape is influencing the gamma knife market by emphasizing safety and efficacy. Stricter approval processes may encourage manufacturers to enhance product quality and innovation, thereby impacting the competitive dynamics within the market.

US Gamma Knife Market Drivers

Supportive Reimbursement Policies

Supportive reimbursement policies are playing a pivotal role in the growth of the gamma knife market. Insurance coverage for gamma knife procedures is becoming more prevalent, as payers recognize the cost-effectiveness and clinical benefits of this treatment modality. The Centers for Medicare & Medicaid Services (CMS) have established reimbursement frameworks that facilitate access to gamma knife treatments for patients. This financial support encourages healthcare providers to invest in gamma knife technology, knowing that they will be compensated for the services rendered. As reimbursement policies continue to evolve in favor of advanced treatment options, the gamma knife market is expected to thrive, driven by increased accessibility and affordability for patients.

Rising Incidence of Brain Disorders

The gamma knife market is experiencing growth due to the increasing incidence of brain disorders such as tumors and vascular malformations. According to the National Cancer Institute, brain tumors account for approximately 1.4% of all cancers in the US, with an estimated 24,000 new cases diagnosed annually. This rising prevalence necessitates advanced treatment options, positioning gamma knife technology as a preferred choice for patients and healthcare providers. The non-invasive nature of gamma knife procedures, coupled with their effectiveness in targeting tumors, enhances their appeal in the gamma knife market. As more healthcare facilities adopt this technology, the market is likely to expand, driven by the need for efficient and effective treatment modalities for brain disorders.

Increased Awareness of Treatment Options

Awareness regarding advanced treatment options for brain disorders is rising among patients and healthcare professionals, positively impacting the gamma knife market. Educational initiatives and outreach programs by medical associations are informing the public about the benefits of non-invasive treatments. As patients become more informed, they are more likely to seek out gamma knife procedures, which are known for their precision and minimal recovery time. This shift in patient behavior is likely to drive demand for gamma knife technology, as healthcare providers respond to the growing interest in effective treatment alternatives. Consequently, the gamma knife market is expected to benefit from this heightened awareness and patient engagement.

Technological Innovations in Radiation Therapy

Technological innovations in radiation therapy are significantly influencing the gamma knife market. Advances in imaging techniques and treatment planning software have enhanced the precision and effectiveness of gamma knife procedures. For instance, the integration of MRI and CT imaging allows for better tumor localization, improving treatment outcomes. The market is witnessing the introduction of new gamma knife models that offer enhanced features, such as real-time imaging and adaptive treatment planning. These innovations not only improve patient safety but also increase the efficiency of treatment delivery, making gamma knife technology more attractive to healthcare providers. As a result, the gamma knife market is likely to expand as these technological advancements continue to evolve.

Growing Investment in Healthcare Infrastructure

Investment in healthcare infrastructure is a crucial driver for the gamma knife market. The US government and private sector are increasingly allocating funds to enhance healthcare facilities, particularly in neurosurgery and oncology departments. Reports indicate that healthcare spending in the US is projected to reach $6 trillion by 2027, with a significant portion directed towards advanced medical technologies. This investment facilitates the acquisition of gamma knife systems, which are essential for providing cutting-edge treatment options. As hospitals and clinics upgrade their equipment to meet patient demand, the gamma knife market is poised for growth, reflecting the broader trend of modernization in healthcare infrastructure.

Market Segment Insights

By Disease Indication: Brain Metastasis (Largest) vs. Trigeminal Neuralgia (Fastest-Growing)

The US gamma knife market is witnessing significant market share distribution among various disease indications. Brain Metastasis stands as the largest segment, driven by the rising prevalence of metastatic cancer in the brain, accounting for a substantial percentage of procedures performed. Other segments such as Cancer, Arteriovenous Malformation, Trigeminal Neuralgia, and Others are also contributing to the market dynamics, albeit at varying scales of share and growth potential. Growth trends within this segment are largely influenced by advancements in gamma knife technology, which enhance treatment efficacy and patient outcomes. The increasing awareness and adoption of non-invasive treatment methods further stimulate demand. Furthermore, Trigeminal Neuralgia is emerging as the fastest-growing segment due to heightened recognition of its impact, driving the need for effective and precise treatment options in the market.

Brain Metastasis (Dominant) vs. Trigeminal Neuralgia (Emerging)

Brain Metastasis is characterized by the infiltration of cancer cells from other parts of the body into the brain, making it a critical and dominant indication in the gamma knife segment. Patients with this condition typically require targeted therapies that minimize damage to surrounding healthy tissue, something that gamma knife radiosurgery excels at providing. In contrast, Trigeminal Neuralgia is gaining traction as an emerging indication, as its significant impact on the quality of life prompts increased clinical attention. New innovative techniques in gamma knife treatment are making it more accessible for managing Trigeminal Neuralgia, thus expanding its share in the market and highlighting the growing demand for effective pain management solutions.

By Anatomy: Head (Largest) vs. Neck (Fastest-Growing)

In the US gamma knife market, the distribution of market share among the anatomy segments reveals that the Head segment holds the largest share, largely due to its prevalent usage in treating brain tumors and other neurological conditions. The Neck segment, while smaller, is gaining traction as more clinicians recognize the effectiveness of gamma knife technology for conditions affecting this area, contributing to its increasing market presence. Growth trends indicate a notable shift towards the Neck segment, which is seeing a rise in demand driven by advancements in medical technologies and an increase in patient awareness. As healthcare providers expand their applications of gamma knife technology, particularly for metastatic lesions and functional disorders in the neck, this segment is projected to be the fastest-growing. This shift signifies a broader acceptance and recognition of the versatility of gamma knife treatments beyond traditional uses.

Head (Dominant) vs. Neck (Emerging)

The Head segment of the US gamma knife market is characterized by its dominance owing to the high incidence of brain-related conditions, necessitating precise and effective treatment methodologies. This segment benefits from established protocols and a robust foundation of clinical research supporting gamma knife procedures. Conversely, the Neck segment is emerging as a vital player, driven by advancements that allow for more effective treatments of complex conditions in this area. While still in a growth phase, increasing clinical trials and positive patient outcomes are bolstering its position, attracting both clinical interest and investment. The innovative approaches within neck treatments signify a dynamic shift in treatment paradigms, promising to enhance patient care and broaden the market scope in the coming years.

Get more detailed insights about US Gamma Knife Market

Key Players and Competitive Insights

The gamma knife market exhibits a dynamic competitive landscape characterized by rapid technological advancements and a growing emphasis on precision medicine. Key players such as Elekta AB (SE), Accuray Incorporated (US), and Varian Medical Systems (US) are at the forefront, leveraging innovation and strategic partnerships to enhance their market positions. Elekta AB (SE) focuses on expanding its product portfolio through continuous research and development, while Accuray Incorporated (US) emphasizes the integration of artificial intelligence (AI) in its treatment planning systems. Varian Medical Systems (US) is actively pursuing collaborations with healthcare providers to improve patient outcomes, thereby shaping a competitive environment that prioritizes technological sophistication and patient-centric solutions.

The business tactics employed by these companies include localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies like Elekta, Accuray, and Varian creates a competitive atmosphere where innovation and strategic positioning are paramount.

In October 2025, Elekta AB (SE) announced a partnership with a leading healthcare institution to develop a next-generation gamma knife system that incorporates advanced imaging technologies. This strategic move is likely to enhance Elekta's product offerings and solidify its position as a leader in the market, as it aligns with the growing demand for precision in stereotactic radiosurgery.

In September 2025, Accuray Incorporated (US) launched a new AI-driven software platform designed to streamline treatment planning for gamma knife procedures. This initiative not only reflects Accuray's commitment to innovation but also positions the company to meet the increasing expectations of healthcare providers for efficiency and accuracy in treatment delivery.

In August 2025, Varian Medical Systems (US) expanded its collaboration with a prominent research university to explore the integration of machine learning algorithms in gamma knife treatments. This partnership is indicative of Varian's strategic focus on harnessing cutting-edge technology to improve treatment efficacy and patient outcomes, thereby enhancing its competitive edge in the market.

As of November 2025, current trends in the gamma knife market are increasingly defined by digitalization, sustainability, and the integration of AI technologies. Strategic alliances among key players are shaping the landscape, fostering innovation and enhancing operational capabilities. The competitive differentiation is likely to evolve from traditional price-based competition towards a focus on technological advancements, reliability in supply chains, and the ability to deliver superior patient care. This shift underscores the importance of innovation as a critical driver of success in the gamma knife market.

Key Companies in the US Gamma Knife Market market include

Industry Developments

Recent developments in the US Gamma Knife Market highlight significant advancements and investments among key players. Notably, in September 2023, Accuray announced an expansion of its radiation therapy solutions, aimed at enhancing precision treatment for patients with brain tumors. Similarly, Elekta introduced innovative software enhancements to optimize treatment planning and patient workflow for Gamma Knife procedures. Furthermore, in July 2023, General Electric and Philips Healthcare collaborated to enhance imaging technologies, improving the integration of diagnostic and treatment modalities in Gamma Knife applications.

In terms of Mergers and Acquisitions, November 2022 saw Varian Medical Systems acquire the assets of a leading software company to bolster its portfolio in image-guided radiation therapy, a move that could strengthen its Gamma Knife offerings. The US Gamma Knife Market has experienced growth due to rising incidences of brain disorders, with multiple companies, including Brainlab and Stereotactic Brain Perfusion, innovating their product lines to meet advanced patient care standards. Over the past three years, the market has noticeably expanded, driven by technological innovations and partnerships among leading companies, establishing a robust landscape in the realm of stereotactic radiosurgery.

Future Outlook

US Gamma Knife Market Future Outlook

The Gamma Knife Market is projected to grow at 5.41% CAGR from 2024 to 2035, driven by technological advancements, increasing cancer prevalence, and rising healthcare expenditure.

New opportunities lie in:

  • Expansion of telemedicine services for remote consultations
  • Development of advanced imaging integration with gamma knife systems
  • Partnerships with insurance providers for enhanced reimbursement models

By 2035, the gamma knife market is expected to achieve substantial growth and innovation.

Market Segmentation

US Gamma Knife Market Anatomy Outlook

  • Head
  • Neck
  • Others

US Gamma Knife Market Disease Indication Outlook

  • Brain Metastasis
  • Cancer
  • Arteriovenous Malformation
  • Trigeminal Neuralgia
  • Others

Report Scope

MARKET SIZE 2024 140.0(USD Million)
MARKET SIZE 2025 147.57(USD Million)
MARKET SIZE 2035 250.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 5.41% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Elekta AB (SE), Accuray Incorporated (US), Varian Medical Systems (US), Brainlab AG (DE), MediTech (US), Nicolet Biomedical (US), Shenzhen Huikang Medical (CN), Stereotactic Radiosurgery (US)
Segments Covered Disease Indication, Anatomy
Key Market Opportunities Advancements in precision targeting technologies enhance treatment efficacy in the gamma knife market.
Key Market Dynamics Technological advancements and regulatory changes drive growth in the gamma knife market, enhancing treatment options and patient outcomes.
Countries Covered US

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FAQs

What was the expected market size of the US Gamma Knife Market in 2024?

The US Gamma Knife Market was expected to be valued at 120.0 million USD in 2024.

What is the projected value of the US Gamma Knife Market by 2035?

By 2035, the US Gamma Knife Market is projected to reach a value of 210.0 million USD.

What is the expected CAGR for the US Gamma Knife Market from 2025 to 2035?

The expected CAGR for the US Gamma Knife Market from 2025 to 2035 is 5.219%.

Which disease indications contribute the most to the US Gamma Knife Market?

The major disease indications contributing to the market are Brain Metastasis, Cancer, Arteriovenous Malformation, and Trigeminal Neuralgia.

What will be the market value for Brain Metastasis in 2035?

In 2035, the market value for Brain Metastasis is expected to be 70.0 million USD.

Who are the key players operating in the US Gamma Knife Market?

Key players in the US Gamma Knife Market include Toshiba Medical Systems, NeuroLogica, Varian Medical Systems, and Elekta.

How much of the market share does Cancer hold in 2024?

In 2024, the market share for Cancer was valued at 30.0 million USD.

What market value was attributed to Arteriovenous Malformation in 2024?

The market value attributed to Arteriovenous Malformation in 2024 was 20.0 million USD.

What challenges may affect the growth of the US Gamma Knife Market?

Challenges that may affect the growth include regulatory hurdles and competition from alternative treatment technologies.

What is the estimated market size for Trigeminal Neuralgia by 2035?

By 2035, the estimated market size for Trigeminal Neuralgia is expected to be 25.0 million USD.

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