×
Request Free Sample ×

Kindly complete the form below to receive a free sample of this Report

Leading companies partner with us for data-driven Insights

clients tt-cursor
Hero Background

US Ankylosing Spondylitis Treatment Market

ID: MRFR/HC/14347-HCR
100 Pages
Rahul Gotadki
October 2025

US Ankylosing Spondylitis Treatment Market Research Report By Treatment Type (Non-Steroidal Anti-Inflammatory Drugs, Tumor Necrosis Factor Inhibitors, Interleukin Inhibitors, Analgesics, Disease Modifying Anti-Rheumatic Drugs), By Route of Administration (Oral, Injectable, Topical), By Patient Type (Adults, Pediatric) and By Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy) - Forecast to 2035

Share:
Download PDF ×

We do not share your information with anyone. However, we may send you emails based on your report interest from time to time. You may contact us at any time to opt-out.

US Ankylosing Spondylitis Treatment Market Infographic
Purchase Options

US Ankylosing Spondylitis Treatment Market Summary

As per analysis, the US ankylosing spondylitis treatment market size was estimated at 1211.62 USD Million in 2024. The US ankylosing spondylitis-treatment market is projected to grow from 1270.99 USD Million in 2025 to 2051.07 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 4.9% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US ankylosing spondylitis-treatment market is experiencing a transformative shift towards innovative therapies and enhanced patient care.

  • The rise of biologic therapies is reshaping treatment paradigms, particularly in the largest segment of biologics.
  • An increased focus on early diagnosis is driving better patient outcomes and engagement in the fastest-growing segment of digital health solutions.
  • Adoption of digital health solutions is facilitating remote monitoring and personalized care for patients with ankylosing spondylitis.
  • Key market drivers include the growing prevalence of ankylosing spondylitis and advancements in treatment modalities, which are propelling market growth.

Market Size & Forecast

2024 Market Size 1211.62 (USD Million)
2035 Market Size 2051.07 (USD Million)

Major Players

AbbVie (US), Amgen (US), Bristol-Myers Squibb (US), Johnson & Johnson (US), Novartis (CH), Pfizer (US), Roche (CH), Sanofi (FR), UCB (BE)

US Ankylosing Spondylitis Treatment Market Trends

The ankylosing spondylitis treatment market is currently experiencing notable shifts. These shifts are driven by advancements in therapeutic options and a growing understanding of the disease. Recent developments in biologic therapies, particularly tumor necrosis factor (TNF) inhibitors and interleukin inhibitors, have transformed treatment paradigms, offering patients improved outcomes and quality of life. Additionally, the increasing prevalence of ankylosing spondylitis among the population has prompted healthcare providers to prioritize early diagnosis and intervention, which may lead to better management of the condition. As awareness of ankylosing spondylitis rises, patients are more likely to seek medical advice, thereby expanding the market further. Moreover, the integration of digital health technologies into treatment plans appears to be gaining traction. Telemedicine and mobile health applications are facilitating remote consultations and monitoring, which could enhance patient engagement and adherence to treatment regimens. This trend may also help in addressing the challenges posed by limited access to specialized care in certain regions. Overall, the ankylosing spondylitis-treatment market is poised for growth, driven by innovative therapies, increased awareness, and the adoption of technology in patient management.

Rise of Biologic Therapies

The introduction of biologic therapies has significantly altered treatment approaches within the ankylosing spondylitis-treatment market. These medications, which target specific components of the immune system, have shown efficacy in reducing inflammation and improving patient outcomes. As more patients gain access to these advanced therapies, the market is likely to expand, reflecting a shift towards personalized medicine.

Increased Focus on Early Diagnosis

There is a growing emphasis on the importance of early diagnosis in the ankylosing spondylitis-treatment market. Healthcare professionals are increasingly recognizing that timely intervention can lead to better long-term outcomes for patients. This trend may drive the development of new diagnostic tools and protocols, ultimately enhancing patient care and treatment effectiveness.

Adoption of Digital Health Solutions

The integration of digital health solutions is increasingly prevalent in the ankylosing spondylitis treatment market. Telehealth services and mobile applications are facilitating better communication between patients and healthcare providers. This trend may improve treatment adherence and patient engagement, particularly for those in remote areas or with limited access to specialized care.

US Ankylosing Spondylitis Treatment Market Drivers

Increased Healthcare Expenditure

Rising healthcare expenditure in the US is a significant driver for the ankylosing spondylitis-treatment market. With healthcare spending projected to reach $6 trillion by 2027, there is a growing emphasis on managing chronic conditions such as ankylosing spondylitis. This increase in expenditure allows for greater access to advanced treatment options, including biologics and other innovative therapies. Additionally, insurance coverage for these treatments is improving, which further facilitates patient access. As more patients seek effective management strategies for their condition, the market is expected to expand, potentially leading to a CAGR of around 5% in the coming years. This trend underscores the importance of financial resources in shaping treatment availability.

Advancements in Treatment Modalities

Innovations in treatment modalities are significantly influencing the ankylosing spondylitis-treatment market. The introduction of novel biologic agents and targeted therapies has transformed the landscape of treatment options available to patients. These advancements not only improve patient outcomes but also expand the market by attracting investment from pharmaceutical companies. For instance, the market for biologics is projected to reach approximately $5 billion by 2027, reflecting a growing interest in advanced therapies. Furthermore, the development of personalized medicine approaches may enhance treatment efficacy, thereby increasing patient adherence and satisfaction. As a result, the market is likely to experience sustained growth driven by these advancements.

Regulatory Support for New Therapies

Regulatory support for the approval of new therapies is a critical driver for the ankylosing spondylitis-treatment market. The US Food and Drug Administration (FDA) has been actively facilitating the development and approval of innovative treatments, including biologics and biosimilars. This supportive regulatory environment encourages pharmaceutical companies to invest in research and development, leading to a broader range of treatment options for patients. The expedited approval processes for breakthrough therapies may result in a faster market entry for new products, thereby enhancing competition and potentially lowering treatment costs. As a result, the market is likely to benefit from increased availability of effective therapies, which could drive growth in the coming years.

Rising Awareness and Education Initiatives

The rise in awareness and education initiatives regarding ankylosing spondylitis is a pivotal driver for the ankylosing spondylitis-treatment market. Organizations and healthcare providers are increasingly focusing on educating both patients and healthcare professionals about the disease, its symptoms, and available treatment options. This heightened awareness is likely to lead to earlier diagnosis and treatment, which can significantly improve patient outcomes. As more individuals recognize the importance of seeking treatment, the demand for therapies is expected to rise. Consequently, this trend may contribute to a market growth rate of approximately 4% over the next few years, as more patients engage with healthcare systems for management of their condition.

Growing Prevalence of Ankylosing Spondylitis

The increasing prevalence of ankylosing spondylitis in the US is a crucial driver for the ankylosing spondylitis-treatment market. Recent estimates suggest that approximately 0.1-0.5% of the US population is affected by this condition, leading to a heightened demand for effective treatment options. As awareness of the disease grows, more individuals are seeking medical attention, which in turn drives the market for therapies. The rising number of diagnosed cases is expected to contribute to a compound annual growth rate (CAGR) of around 6% in the treatment market over the next few years. This trend indicates a robust market potential as healthcare providers and pharmaceutical companies focus on developing innovative therapies to address the needs of this patient population.

Market Segment Insights

By Type: Tumor Necrosis Factor Inhibitors (Largest) vs. Interleukin Inhibitors (Fastest-Growing)

In the US ankylosing spondylitis-treatment market, the market share distribution among type segments reveals that Tumor Necrosis Factor Inhibitors lead significantly, capturing the largest share due to their established efficacy in managing symptoms. Non-Steroidal Anti-Inflammatory Drugs and Disease Modifying Anti-Rheumatic Drugs follow, contributing to the overall treatment landscape, while Analgesics hold a smaller, yet essential, role for pain management. Interleukin Inhibitors are emerging as noteworthy players due to increasing adoption and recognition in recent years. Growth trends in the segment indicate a promising shift towards biologics, particularly Interleukin Inhibitors, which are noted as the fastest-growing segment. This uptick is fueled by advancements in biotechnology and increasing investments towards innovative therapies that showcase safety and effective symptom control. The rising prevalence of ankylosing spondylitis also drives demand across all types, as healthcare providers seek diverse treatment options for better patient outcomes.

Tumor Necrosis Factor Inhibitors (Dominant) vs. Interleukin Inhibitors (Emerging)

Tumor Necrosis Factor Inhibitors dominate the US ankylosing spondylitis-treatment market due to longstanding clinical efficacy and a well-established patient base. They are widely prescribed for their ability to alleviate symptoms and improve quality of life, making them the go-to option among rheumatologists. In contrast, Interleukin Inhibitors are emerging as a significant alternative, particularly among patients who do not respond well to traditional therapies. Their novel mechanisms of action and improved safety profiles are leading to increased interest, positioning them as a frontrunner for future growth in the market. The differentiation in treatment approaches between these two segments highlights the ongoing evolution of therapy choices available for ankylosing spondylitis patients.

By Route of Administration: Oral (Largest) vs. Injectable (Fastest-Growing)

In the US ankylosing spondylitis-treatment market, the route of administration segment exhibits a diverse distribution of market share among oral, injectable, and topical treatments. Currently, oral administration leading the segment accounts for a significant share, attributed to its ease of use and patient preference. Injectable options, while smaller in share, are rapidly gaining traction due to advancements in formulation and delivery methods, appealing to a subset of patients that require more intensive medical intervention. Growth trends within the route of administration segment are primarily driven by innovation in drug formulation and a growing emphasis on patient compliance. The rise of biologic therapies and targeted treatments being administered via injection is reshaping the market landscape. Additionally, the increasing incidence of ankylosing spondylitis in the population fosters a progressive shift towards treatments that offer greater efficacy, with injectables emerging as a preferred choice for many patients looking for effective management of their condition.

Oral (Dominant) vs. Injectable (Emerging)

The oral route of administration remains dominant in the treatment landscape for ankylosing spondylitis, favored for its convenience and non-invasive nature. Oral medications are often the first-line treatment, allowing patients to easily manage their intake at home. In contrast, injectables are quickly becoming an emerging option as they promise faster onset of action and improved efficacy for managing severe symptoms. This shift towards injectable treatments is particularly pronounced among patients seeking rapid relief and who are willing to adopt injectable therapies. As the US ankylosing spondylitis-treatment market evolves, the dynamic between these routes continues to shape patient choices and treatment protocols.

By Patient Type: Adults (Largest) vs. Pediatric (Fastest-Growing)

In the US ankylosing spondylitis-treatment market, the patient type segment is predominantly composed of adults, who hold a significant majority share. This adult demographic has been recognized for its stable demand for treatment options, reflecting the chronic nature of ankylosing spondylitis in this age group. While The pediatric segment is smaller. However, it is gaining traction as awareness of early diagnosis and treatment for young patients increases. The growth trends for this segment indicate a burgeoning interest in pediatric treatment options. As healthcare providers emphasize early intervention, the pediatric segment is projected to expand at a faster rate. Variables driving this growth include increased advocacy for pediatric care, advancements in treatment modalities tailored for younger patients, and a heightened focus on reducing long-term complications through early therapies.

Adults (Dominant) vs. Pediatric (Emerging)

The adult segment in the US ankylosing spondylitis-treatment market remains dominant due to a well-established routine of monitoring and management within this demographic. Adults typically require a range of treatment options, including biologics and physical therapy, as they are more susceptible to chronic complications. On the other hand, the pediatric segment is emerging, fueled by rising awareness of ankylosing spondylitis among children and adolescents. This segment is characterized by a growing need for specialized treatments and care strategies designed for younger patients, ensuring they receive timely interventions to manage their condition effectively. The success of pediatric treatment options relies on continued research and the development of age-appropriate therapies.

By Distribution Channel: Hospital Pharmacy (Largest) vs. Online Pharmacy (Fastest-Growing)

Within the US ankylosing spondylitis-treatment market, the distribution of treatments through channels reveals that Hospital Pharmacy holds the largest market share. This segment is critical due to its comprehensive patient care and direct access to specialist treatment options. Retail Pharmacy follows, providing significant accessibility, while Online Pharmacy is emerging rapidly, reflecting changing consumer preferences towards convenience and availability. Growth trends indicate a substantial shift towards Online Pharmacy, driven by the increased adoption of e-commerce in healthcare and the demand for at-home treatment options. The Hospital Pharmacy segment remains strong due to the close relationship with healthcare providers and immediate availability of critical medications. This dynamic is reshaping the competitive landscape as patients seek more flexible treatment options.

Hospital Pharmacy (Dominant) vs. Online Pharmacy (Emerging)

The Hospital Pharmacy segment is characterized by its strong presence in inpatient care settings, offering specialized treatments that are vital for acute cases of ankylosing spondylitis. It plays a dominant role due to its ability to provide immediate access to therapies, often in conjunction with effective monitoring from healthcare professionals. In contrast, Online Pharmacy is rapidly emerging as a preferred option for many patients who value convenience and discretion in managing their health. This segment leverages technological advancements to facilitate seamless ordering and delivery processes, appealing particularly to younger demographics and those facing mobility challenges.

Get more detailed insights about US Ankylosing Spondylitis Treatment Market

Key Players and Competitive Insights

The ankylosing spondylitis-treatment market is characterized by a dynamic competitive landscape, driven by increasing prevalence rates and a growing demand for effective therapies. Key players such as AbbVie (US), Amgen (US), and Pfizer (US) are actively engaged in innovation and strategic partnerships to enhance their market positions. AbbVie (US) focuses on expanding its portfolio through research and development, particularly in biologics, while Amgen (US) emphasizes the integration of digital health solutions into its treatment offerings. Pfizer (US) is pursuing collaborations with biotechnology firms to leverage cutting-edge technologies, thereby shaping a competitive environment that prioritizes innovation and patient-centric solutions.

The market structure appears moderately fragmented, with several players vying for market share. Companies are adopting various business tactics, such as localizing manufacturing and optimizing supply chains, to enhance operational efficiency. This collective influence of key players fosters a competitive atmosphere where agility and responsiveness to market needs are paramount. The presence of multiple stakeholders encourages a diverse range of treatment options, ultimately benefiting patients.

In October 2025, AbbVie (US) announced a strategic partnership with a leading digital health company to develop a mobile application aimed at improving patient adherence to treatment regimens. This initiative underscores AbbVie's commitment to integrating technology into patient care, potentially enhancing treatment outcomes and patient engagement. Such collaborations may also position AbbVie favorably in a market increasingly focused on holistic patient management.

In September 2025, Pfizer (US) launched a new clinical trial for a novel therapy targeting ankylosing spondylitis, which aims to address unmet medical needs in this patient population. This move reflects Pfizer's strategy to innovate within the therapeutic landscape, potentially expanding its market share by offering cutting-edge solutions. The trial's outcomes could significantly influence treatment protocols and patient access to advanced therapies.

In August 2025, Amgen (US) unveiled a new initiative to streamline its supply chain processes, focusing on sustainability and efficiency. This strategic action not only aims to reduce operational costs but also aligns with the growing emphasis on environmentally responsible practices within the pharmaceutical industry. By enhancing supply chain reliability, Amgen may improve its competitive edge in a market where timely access to therapies is critical.

As of November 2025, current trends in the ankylosing spondylitis-treatment market indicate a shift towards digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are increasingly shaping the competitive landscape, fostering innovation and collaboration among key players. The evolution of competitive differentiation appears to be moving away from price-based competition towards a focus on technological advancements, innovative treatment solutions, and robust supply chain management. This shift may ultimately redefine how companies position themselves in the market, emphasizing the importance of adaptability and forward-thinking strategies.

Key Companies in the US Ankylosing Spondylitis Treatment Market market include

Industry Developments

The US Ankylosing Spondylitis Treatment Market has recently seen significant developments, particularly surrounding new therapeutic options and competitive strategies among key players like Celgene, Novartis, Takeda, Merck, Eli Lilly, Bristol Myers Squibb, Gilead Sciences, Sandoz, Pfizer, Amgen, AbbVie, Roche, Sanofi, Johnson and Johnson, and UCB. In September 2023, Eli Lilly announced promising results from a clinical trial on a novel monoclonal antibody aimed at improving patient outcomes, indicating strong growth potential for their treatment pipeline.

Notably, in July 2023, AbbVie acquired an innovative biotech firm to enhance its Research and Development capabilities in inflammatory diseases, reflecting strategic moves to solidify their market position.

Market valuation for Ankylosing Spondylitis treatments is projected to grow significantly, driven by an increasing prevalence of the disease among the US population and advancements in biological therapies. The integration of biosimilars into treatment protocols is also on the rise, as seen with Sandoz and Pfizer, aiming to make treatments more accessible. Over the last few years, robust investment in biologics and targeted therapies has transformed the treatment landscape, aligning with the growing need for effective solutions in managing Ankylosing Spondylitis.

Future Outlook

US Ankylosing Spondylitis Treatment Market Future Outlook

The Ankylosing Spondylitis Treatment Market is projected to grow at a 4.9% CAGR from 2024 to 2035, driven by advancements in biologics, increasing patient awareness, and enhanced diagnostic tools.

New opportunities lie in:

  • Development of personalized biologic therapies for targeted treatment
  • Expansion of telehealth services for remote patient management
  • Investment in AI-driven diagnostic tools for early detection

By 2035, the market is expected to achieve substantial growth, reflecting evolving treatment paradigms.

Market Segmentation

US Ankylosing Spondylitis Treatment Market Type Outlook

  • Non-Steroidal Anti-Inflammatory Drugs
  • Tumor Necrosis Factor Inhibitors
  • Interleukin Inhibitors
  • Analgesics
  • Disease Modifying Anti-Rheumatic Drugs

US Ankylosing Spondylitis Treatment Market Patient Type Outlook

  • Adults
  • Pediatric

US Ankylosing Spondylitis Treatment Market Distribution Channel Outlook

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

US Ankylosing Spondylitis Treatment Market Route of Administration Outlook

  • Oral
  • Injectable
  • Topical

Report Scope

MARKET SIZE 2024 1211.62(USD Million)
MARKET SIZE 2025 1270.99(USD Million)
MARKET SIZE 2035 2051.07(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 4.9% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled AbbVie (US), Amgen (US), Bristol-Myers Squibb (US), Johnson & Johnson (US), Novartis (CH), Pfizer (US), Roche (CH), Sanofi (FR), UCB (BE)
Segments Covered Type, Route of Administration, Patient Type, Distribution Channel
Key Market Opportunities Advancements in biologics and personalized medicine enhance treatment options in the ankylosing spondylitis-treatment market.
Key Market Dynamics Rising demand for biologics drives innovation and competition in the ankylosing spondylitis-treatment market.
Countries Covered US

Leave a Comment

FAQs

What is the expected market size of the US Ankylosing Spondylitis Treatment Market in 2024?

The US Ankylosing Spondylitis Treatment Market is expected to be valued at 1.03 billion USD in 2024.

What will be the projected market size of the US Ankylosing Spondylitis Treatment Market by 2035?

By 2035, the US Ankylosing Spondylitis Treatment Market is expected to reach 1.72 billion USD.

What is the expected CAGR for the US Ankylosing Spondylitis Treatment Market from 2025 to 2035?

The expected CAGR for the US Ankylosing Spondylitis Treatment Market from 2025 to 2035 is 4.753 percent.

Which treatment type is projected to have the largest market share in 2024?

In 2024, the Non-Steroidal Anti-Inflammatory Drugs segment is projected to hold the largest market share at 0.39 billion USD.

What is the expected market value for Tumor Necrosis Factor Inhibitors in 2035?

The market value for Tumor Necrosis Factor Inhibitors is expected to be 0.51 billion USD in 2035.

Who are the key players in the US Ankylosing Spondylitis Treatment Market?

Key players in the market include Celgene, Novartis, Takeda, Merck, and Eli Lilly among others.

What market segment is forecasted to grow the fastest from 2025 to 2035?

The Interleukin Inhibitors segment is expected to have a significant growth trajectory during the forecast period from 2025 to 2035.

What will the market size for Disease Modifying Anti-Rheumatic Drugs be in 2035?

The market size for Disease Modifying Anti-Rheumatic Drugs is projected to be 0.15 billion USD in 2035.

What are some challenges currently facing the US Ankylosing Spondylitis Treatment Market?

Challenges in the market include stringent regulatory requirements and high treatment costs.

How does the US Ankylosing Spondylitis Treatment Market compare to global trends?

The US Ankylosing Spondylitis Treatment Market is growing steadily, reflecting global trends of increasing demand for effective treatments for chronic conditions.

Download Free Sample

Kindly complete the form below to receive a free sample of this Report

Compare Licence

×
Features License Type
Single User Multiuser License Enterprise User
Price $4,950 $5,950 $7,250
Maximum User Access Limit 1 User Upto 10 Users Unrestricted Access Throughout the Organization
Free Customization
Direct Access to Analyst
Deliverable Format
Platform Access
Discount on Next Purchase 10% 15% 15%
Printable Versions