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UK RNA-based Therapeutics Market

ID: MRFR/HC/50891-HCR
200 Pages
Garvit Vyas
October 2025

UK RNA-Based Therapeutics Market Research Report By Technology (RNA Interference, Antisense Oligonucleotides, mRNA Therapeutics, CRISPR Technology), By Application (Oncology, Infectious Diseases, Genetic Disorders, Cardiovascular Diseases), By End Use (Pharmaceutical Companies, Research Institutions, Contract Research Organizations) and By Delivery Method (Liposomes, Nanoparticles, Viral Vectors, Electroporation) - Growth & Industry Forecast 2025 To 2035

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UK RNA-based Therapeutics Market Infographic
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UK RNA-based Therapeutics Market Summary

As per Market Research Future analysis, the UK RNA-based Therapeutics Market size was estimated at 659.38 USD Million in 2024. The RNA-based therapeutics market is projected to grow from 699.61 USD Million in 2025 to 1265.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 6% during the forecast period 2025 - 2035

Key Market Trends & Highlights

The UK RNA-based therapeutics market is poised for substantial growth driven by innovation and collaboration.

  • The market is witnessing increased investment in research and development, indicating a robust commitment to advancing RNA therapeutics.
  • Regulatory support and frameworks are evolving, facilitating a more conducive environment for RNA-based therapies.
  • Collaboration between academia and industry is becoming more prevalent, enhancing the development pipeline for RNA therapeutics.
  • The growing demand for personalized medicine and technological advancements in RNA delivery systems are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 659.38 (USD Million)
2035 Market Size 1265.0 (USD Million)
CAGR (2025 - 2035) 6.1%

Major Players

Moderna (US), BioNTech (DE), Alnylam Pharmaceuticals (US), Ionis Pharmaceuticals (US), CureVac (DE), Sangamo Therapeutics (US), Arcturus Therapeutics (US), Translate Bio (US)

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Enabled $4.3B Revenue Impact for Fortune 500 and Leading Multinationals
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UK RNA-based Therapeutics Market Trends

The UK RNA-based Therapeutics Market is currently experiencing a transformative phase, driven by advancements in genetic research and technology. The increasing understanding of RNA's role in cellular processes has led to innovative therapeutic approaches, particularly in treating genetic disorders and cancers. Regulatory bodies in the UK are actively supporting the development of these therapies, which may enhance patient outcomes and provide new avenues for treatment. Furthermore, collaborations between academic institutions and biotechnology firms are fostering a vibrant ecosystem for research and development, potentially accelerating the introduction of novel therapies into the market. In addition, the rna based-therapeutics market is witnessing a surge in investment, as stakeholders recognize the potential of RNA-based solutions. The UK government has initiated funding programs aimed at bolstering research initiatives in this field, which could lead to breakthroughs in treatment methodologies. As the market evolves, it appears that the integration of artificial intelligence and machine learning in drug discovery processes may further streamline the development of RNA-based therapies, enhancing their efficacy and safety profiles. Overall, the landscape of the rna based-therapeutics market is poised for significant growth, driven by innovation and strategic partnerships.

Increased Investment in Research and Development

The rna based-therapeutics market is witnessing heightened investment from both public and private sectors. This influx of funding is primarily directed towards research initiatives aimed at discovering novel RNA-based treatments. The UK government has established various funding programs to support these efforts, which may lead to accelerated advancements in therapeutic options.

Regulatory Support and Framework

Regulatory bodies in the UK are actively creating supportive frameworks for the rna based-therapeutics market. This includes streamlined approval processes for RNA-based therapies, which could facilitate quicker access to innovative treatments for patients. Such regulatory support is crucial for fostering a conducive environment for market growth.

Collaboration Between Academia and Industry

There is a notable trend of collaboration between academic institutions and biotechnology companies within the rna based-therapeutics market. These partnerships are essential for translating research findings into practical applications. By leveraging academic expertise and industry resources, these collaborations may enhance the development of effective RNA-based therapies.

UK RNA-based Therapeutics Market Drivers

Supportive Regulatory Environment

A supportive regulatory environment is fostering growth in the rna based-therapeutics market. The UK regulatory agencies are actively working to streamline the approval processes for RNA-based therapies, thereby encouraging innovation and investment in this sector. Initiatives aimed at expediting clinical trials and providing clear guidelines for the development of RNA therapeutics are enhancing the attractiveness of this market for investors and developers alike. This regulatory support is crucial for bringing new therapies to market more efficiently, which is expected to contribute to a projected market growth of approximately 12% annually over the next five years. The proactive stance of regulatory bodies is likely to bolster confidence among stakeholders in the rna based-therapeutics market.

Growing Demand for Personalized Medicine

The RNA-based therapeutics market is experiencing a notable surge in demand for personalized medicine, driven by advancements in genomics and biotechnology. This shift towards tailored treatments is reshaping the landscape of healthcare in the UK. As patients increasingly seek therapies that are specifically designed to address their unique genetic profiles, the rna based-therapeutics market is positioned to benefit significantly. The market is projected to reach approximately £2 billion by 2026, reflecting a compound annual growth rate (CAGR) of around 15%. This growth is indicative of the increasing recognition of the potential of rna-based therapies to provide more effective and targeted treatment options, thereby enhancing patient outcomes and satisfaction.

Increasing Prevalence of Genetic Disorders

The rising incidence of genetic disorders in the UK is significantly influencing the rna based-therapeutics market. Conditions such as cystic fibrosis, muscular dystrophy, and various rare diseases are becoming more prevalent, necessitating innovative treatment solutions. RNA-based therapies offer promising avenues for addressing these genetic challenges, as they can directly target the underlying genetic mutations. The UK government has recognized this need and is investing in initiatives to support the development of RNA therapeutics. This focus on addressing genetic disorders is likely to propel the market forward, with projections indicating a potential market size of £1.8 billion by 2027, driven by the urgent demand for effective therapies.

Rising Investment from Biopharmaceutical Companies

The rna based-therapeutics market is witnessing a surge in investment from biopharmaceutical companies, which is driving innovation and development in this field. As these companies recognize the potential of RNA-based therapies to address unmet medical needs, they are allocating substantial resources towards research and development. This influx of capital is facilitating the advancement of novel RNA therapeutics, including mRNA vaccines and gene editing technologies. The UK is becoming a hub for such investments, with estimates suggesting that funding in this sector could exceed £1 billion by 2025. This trend indicates a strong belief in the future of RNA therapeutics, which is likely to enhance the overall market landscape.

Technological Advancements in RNA Delivery Systems

Technological innovations in RNA delivery systems are playing a crucial role in the expansion of the rna based-therapeutics market. Enhanced delivery mechanisms, such as lipid nanoparticles and viral vectors, are improving the efficacy and safety of RNA therapies. These advancements facilitate the precise targeting of diseased cells while minimizing off-target effects, which is essential for the successful application of RNA therapeutics. The UK is witnessing a rise in research initiatives focused on optimizing these delivery systems, which could potentially lead to more effective treatments for various conditions, including genetic disorders and cancers. As a result, the market is expected to grow at a robust pace, with estimates suggesting a valuation of £1.5 billion by 2025.

Market Segment Insights

By Technology: RNA Interference (Largest) vs. CRISPR Technology (Fastest-Growing)

The UK RNA-based therapeutics market is witnessing a varied distribution of market share across its technology segments. RNA Interference stands out as the largest segment, reflecting its established role in gene silencing and therapeutic applications. Antisense Oligonucleotides also hold a significant share, supported by their unique mechanism of action. Meanwhile, mRNA Therapeutics is gaining traction, mainly due to increased interest in vaccine development and personalized medicine, while CRISPR Technology is emerging rapidly, reflecting its revolutionary applications in gene editing and therapeutic innovations. Growth trends in the technology segment are showing a promising upward trajectory, driven by advancements in genetic research and increased investment in biopharmaceuticals. The demand for RNA-based therapeutics is propelled by the rising incidence of genetic disorders and the need for innovative treatments. Additionally, regulatory support and a favorable funding environment are facilitating the development of CRISPR Technology, positioning it as the fastest-growing segment in this landscape, while RNA Interference maintains its stronghold due to its established efficacy.

Technology: RNA Interference (Dominant) vs. CRISPR Technology (Emerging)

RNA Interference is characterized by its ability to regulate gene expression effectively, making it a dominant player in therapeutic development. Its robust pipeline of applications includes targeting various diseases, particularly in oncology and genetic disorders. Meanwhile, CRISPR Technology, although emerging, has garnered significant attention due to its precision and versatility in gene editing. This technology holds the promise for revolutionary advancements in treating previously untreatable conditions. While RNA Interference continues to dominate with its established methodologies and proven results, CRISPR's innovative approach is rapidly positioning it for future growth and opportunities in the UK rna based-therapeutics market.

By Application: Oncology (Largest) vs. Infectious Diseases (Fastest-Growing)

In the UK RNA-based therapeutics market, the application segments are witnessing a dynamic distribution of market share, with oncology leading as the largest segment due to an increasing focus on developing targeted therapies. This strong emphasis on oncology reflects the significant burden of cancer within the population, steering investments towards innovative therapeutic approaches. Meanwhile, infectious diseases are showing robust potential, especially with rising global attention towards vaccine development and treatment options for emerging viral threats. The growth trends in these segments are influenced by various factors, such as advancements in genetic research and rising healthcare expenditures. Significant R&D efforts are being funneled into both oncology and infectious diseases, propelling the development of personalized medicine and RNA-based solutions. This is coupled with an increased demand for novel therapeutic options, as patients and healthcare providers seek more effective treatments.

Oncology (Dominant) vs. Infectious Diseases (Emerging)

Oncology is currently the dominant segment within the UK rna based-therapeutics market, driven by a vast array of clinical trials and an evolving landscape of therapies that target specific cancer types more effectively. The investments pouring into this area are indicative of its priority status, as stakeholders recognize the urgent need for improved survival rates and quality of life for cancer patients. In contrast, infectious diseases are emerging swiftly due to heightened global awareness of public health threats and the urgent need for innovative treatments and vaccines. This segment benefits from accelerated regulatory pathways and funding support, responding promptly to outbreaks and growing infectious disease challenges, indicating its importance in future market expansion.

By End Use: Pharmaceutical Companies (Largest) vs. Research Institutions (Fastest-Growing)

In the UK RNA-based therapeutics market, Pharmaceutical Companies hold the largest share, commanding significant market influence and driving innovation within the sector. This segment is characterized by its investment in advanced research and development, which fosters a competitive edge in discovering novel therapies. Research Institutions, on the other hand, are emerging rapidly, capitalizing on increased public and private funding to enhance their research capabilities and overall contributions to the market. The growth trends within this segment indicate a robust increase in activity among Research Institutions, driven by collaborative partnerships with Pharmaceutical Companies and a growing emphasis on personalized medicine. The competitive landscape is shaped by the dynamic nature of research funding, technological advancements, and the ongoing need for novel therapeutics in treating complex diseases. Such trends underscore the evolving nature of the UK rna based-therapeutics market, highlighting an exciting phase of growth and opportunity.

Pharmaceutical Companies: Dominant vs. Research Institutions: Emerging

Pharmaceutical Companies are the dominant force in the UK rna based-therapeutics market, leveraging extensive resources to spearhead innovative drug development. Their established presence allows them to navigate regulatory frameworks effectively while prioritizing the commercialization of therapeutic solutions. In contrast, Research Institutions represent an emerging segment characterized by agility and creativity, often operating on the cutting edge of scientific discovery. They are increasingly recognized for their potential to contribute groundbreaking rna therapeutics, facilitated by collaborations with industry players. This synergy not only enhances the output of novel therapies but also enriches the overall landscape of the UK rna based-therapeutics market.

By Delivery Method: Viral Vectors (Largest) vs. Nanoparticles (Fastest-Growing)

The UK rna based-therapeutics market shows a diverse distribution among the delivery methods, with viral vectors holding the largest market share. This segment benefits from established applications and proven efficacy in gene delivery, making it a preferred choice among developers. In contrast, nanoparticles are emerging rapidly, driven by their versatility and ability to target specific cells, which is appealing in therapeutic applications. Growth trends indicate a robust demand for both delivery methods, fueled by increasing investments in research and development. The rising prevalence of genetic disorders and the shift towards personalized medicine underscore the importance of efficient delivery systems. Additionally, advancements in nanoparticle technology enhance their market position, making them a focal point for future innovations in treatment methodologies.

Viral Vectors (Dominant) vs. Nanoparticles (Emerging)

Viral vectors, as the dominant delivery method in the UK rna based-therapeutics market, are preferred due to their high efficiency in delivering therapeutic genes to target cells. Their established regulatory pathways and successful applications in clinical trials bolster their market presence. Meanwhile, nanoparticles are considered an emerging method, gaining traction for their unique properties such as biocompatibility and the ability to encapsulate various types of therapeutics. Their versatility enables targeted delivery, which is crucial for minimizing side effects and maximizing therapeutic effects. The adoption of nanoparticles is expected to grow significantly, driven by innovations that enhance their targeting capabilities and expand their potential applications in the therapeutics landscape.

Get more detailed insights about UK RNA-based Therapeutics Market

Regional Insights

The South America Ostomy Drainage Bags Devices Market is witnessing steady growth across its various regional segments, driven by increasing healthcare expenditure and a rising prevalence of gastrointestinal diseases. Brazil stands out as a key player in this market, with significant healthcare initiatives aimed at improving ostomy care. Mexico follows closely, where an expanding elderly population is pushing the demand for ostomy products. Argentina's market is characterized by growing awareness regarding ostomy care and support from health authorities, fueling adoption rates of drainage bags and related devices.

The Rest of South America region reflects a varied landscape, with each country showing unique needs based on healthcare access and patient education initiatives. Overall, the dynamic nature of this region, coupled with supportive government policies aimed at improving healthcare access, positions the South America Ostomy Drainage Bags Devices Market as a significant area for growth, providing numerous opportunities for manufacturers and suppliers in this sector.

Key Players and Competitive Insights

The rna based-therapeutics market is currently characterized by a dynamic competitive landscape, driven by innovation, strategic partnerships, and a focus on addressing unmet medical needs. Key players such as Moderna (US), BioNTech (DE), and Alnylam Pharmaceuticals (US) are at the forefront, leveraging their technological advancements to enhance therapeutic efficacy. Moderna (US) has positioned itself as a leader in mRNA technology, focusing on expanding its pipeline beyond infectious diseases into areas such as oncology and rare genetic disorders. BioNTech (DE), known for its pioneering work in mRNA vaccines, is also diversifying its portfolio to include personalized cancer therapies, indicating a strategic shift towards precision medicine. Alnylam Pharmaceuticals (US) continues to innovate in the field of RNA interference, emphasizing its commitment to developing transformative therapies for genetic diseases, thereby shaping the competitive environment through its unique approach to gene silencing.In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance operational efficiency and responsiveness to market demands. The market structure appears moderately fragmented, with a mix of established players and emerging biotech firms. This fragmentation allows for a diverse range of therapeutic options, although the collective influence of major players like Moderna (US) and BioNTech (DE) is significant in setting industry standards and driving research and development initiatives.

In October Moderna (US) announced a strategic collaboration with a leading UK-based biotech firm to co-develop mRNA-based therapies for rare diseases. This partnership is expected to enhance Moderna's capabilities in addressing niche markets, thereby expanding its therapeutic reach and reinforcing its competitive position. The collaboration signifies a trend towards leveraging local expertise to accelerate innovation and market entry.

In September BioNTech (DE) unveiled a new facility in the UK dedicated to the production of personalized mRNA cancer therapies. This investment not only underscores BioNTech's commitment to expanding its manufacturing footprint but also highlights the growing importance of localized production in meeting regional healthcare needs. The facility is anticipated to enhance supply chain reliability and reduce time-to-market for innovative therapies.

In August Alnylam Pharmaceuticals (US) received regulatory approval for its latest RNA interference therapy aimed at treating a rare genetic disorder. This approval marks a significant milestone for the company, reinforcing its leadership in the RNA therapeutics space. The successful launch of this therapy is likely to bolster Alnylam's market presence and attract further investment into its pipeline of innovative treatments.

As of November the competitive trends within the rna based-therapeutics market are increasingly influenced by digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are becoming pivotal in shaping the landscape, as companies seek to combine resources and expertise to drive innovation. The shift from price-based competition towards differentiation through technology and supply chain reliability is evident, suggesting that future competitive advantages will hinge on the ability to innovate and deliver high-quality, effective therapies.

Key Companies in the UK RNA-based Therapeutics Market include

Industry Developments

In recent months, the South America Ostomy Drainage Bags Devices Market has seen noteworthy developments, highlighting the region's dynamic healthcare landscape. Companies like Smith and Nephew, B. Braun, and Coloplast have been at the forefront of innovation, with new product launches aimed at improving patient comfort and quality of life. In February 2023, C.R. Bard announced a collaboration with local healthcare providers to enhance product accessibility in Brazil, while Fresenius Kabi has expanded its production facilities in Argentina to cater to the growing demand for ostomy products.

Additionally, the market has experienced a notable increase in valuation, primarily driven by the rising prevalence of chronic diseases, such as colorectal cancer, which necessitate ostomy surgeries. Over the past two years, investment activities have surged, with Atos Medical acquiring a regional competitor in November 2022, further consolidating its market position. Regulatory bodies in South America have also been actively working on policies to streamline the approval process for medical devices, contributing positively to market growth.

The focus is now on providing advanced and accessible healthcare solutions for patients across the region, positioning South America as a critical player in the global ostomy drainage bags devices sector.

Future Outlook

UK RNA-based Therapeutics Market Future Outlook

The RNA Based Therapeutics Market is projected to grow at a 6.1% CAGR from 2025 to 2035, driven by advancements in gene editing, increased R&D investments, and rising demand for personalized medicine.

New opportunities lie in:

  • Development of RNA delivery systems for targeted therapies.
  • Partnerships with biotech firms for innovative RNA-based solutions.
  • Expansion into emerging markets with tailored RNA therapies.

By 2035, the RNA-based therapeutics market is expected to achieve substantial growth and innovation.

Market Segmentation

UK RNA-based Therapeutics Market End Use Outlook

  • Pharmaceutical Companies
  • Research Institutions
  • Contract Research Organizations

UK RNA-based Therapeutics Market Technology Outlook

  • RNA Interference
  • Antisense Oligonucleotides
  • mRNA Therapeutics
  • CRISPR Technology

UK RNA-based Therapeutics Market Application Outlook

  • Oncology
  • Infectious Diseases
  • Genetic Disorders
  • Cardiovascular Diseases

UK RNA-based Therapeutics Market Delivery Method Outlook

  • Liposomes
  • Nanoparticles
  • Viral Vectors
  • Electroporation

Report Scope

MARKET SIZE 2024 659.38(USD Million)
MARKET SIZE 2025 699.61(USD Million)
MARKET SIZE 2035 1265.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 6.1% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Moderna (US), BioNTech (DE), Alnylam Pharmaceuticals (US), Ionis Pharmaceuticals (US), CureVac (DE), Sangamo Therapeutics (US), Arcturus Therapeutics (US), Translate Bio (US)
Segments Covered Technology, Application, End Use, Delivery Method
Key Market Opportunities Advancements in RNA delivery systems enhance therapeutic efficacy and expand treatment options in the rna based-therapeutics market.
Key Market Dynamics Regulatory advancements and technological innovations drive growth in the RNA-based therapeutics market.
Countries Covered UK
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