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UK Microbiome Sequencing Services Market Research Report By Technology (Sequencing by Litigation (SBL), Sequencing by Synthesis (SBS), Short Gun Sequencing, Targeted Gene Sequencing, RNA Sequencing, Others) and By Application (Gastrointestinal Diseases, Infectious Diseases, CNS Diseases, Oncology, Others)- Forecast to 2035


ID: MRFR/HC/52144-HCR | 200 Pages | Author: Garvit Vyas| July 2025

UK Microbiome Sequencing Services Market Overview


As per MRFR analysis, the UK Microbiome Sequencing Services Market Size was estimated at 85.17 (USD Million) in 2023. The UK Microbiome Sequencing Services Market Industry is expected to grow from 93.6(USD Million) in 2024 to 487.32 (USD Million) by 2035. The UK Microbiome Sequencing Services Market CAGR (growth rate) is expected to be around 16.182% during the forecast period (2025 - 2035).


Key UK Microbiome Sequencing Services Market Trends Highlighted


The UK Microbiome Sequencing Services Market is undergoing substantial development as a result of the growing demand for personalized medicine and the advancement of genomic technologies. Healthcare professionals and researchers are increasing their exploration of microbiome analysis due to the growing recognition of the human microbiome's influence on health and disease. In the United Kingdom, public health initiatives are also emphasizing the importance of microbiome research in the comprehension of chronic diseases, resulting in a greater allocation of resources to related studies.


Collaborations between universities and biotech firms in the United Kingdom present opportunities for development, as they promote innovation in microbiome applications in fields such as immune responses, metabolic disorders, and digestive health. In recent years, there has been a discernible trend of escalating investment in microbiome studies from private ventures and funding bodies. The UK government has been promoting research in this field through a variety of health agencies, acknowledging its potential for both economic benefits and health enhancement. Moreover, the incorporation of microbiome data into clinical practice is on the rise, as healthcare providers are attempting to customize treatments based on individual microbiome profiles by utilizing sequencing services.


The trend toward regulatory support for microbiome-based interventions is also significant, which facilitates the introduction of novel products to the market.Furthermore, the expansion of databases that consolidate microbiome sequences improves the comparative knowledge that is accessible to researchers and clinicians, thereby enabling the production of more robust research outputs. In general, the UK Microbiome Sequencing Services Market is poised for further growth, as it is indicative of the nation's dedication to the improvement of health through the development of advanced microbiome research and applications.


UK Microbiome Sequencing Services Market size


Source: Primary Research, Secondary Research, MRFR Database, and Analyst Review


UK Microbiome Sequencing Services Market Drivers


Increasing Demand for Personalized Medicine


The growing emphasis on personalized medicine is a significant driver of the UK Microbiome Sequencing Services Market. The UK government has been investing in initiatives like the NHS Genomic Medicine Service to enhance personalized treatments, aiming to incorporate genomic data to tailor healthcare services according to individual patient needs. Statistics show that personalized medicine can potentially make treatments 30% more effective, enhancing patient outcomes.


As healthcare evolves, the microbe-based approaches will become integral in creating personalized healthcare plans, increasing the demand for microbiome sequencing services. Established organizations like Genomics England are leading these initiatives, and their focus on integrating sequencing technologies within clinical practices is likely to further spur growth in this market sector.


Rising Awareness of Gut Health


There has been a marked increase in public awareness regarding gut health and its connection to overall well-being, driving the requirement for microbiome sequencing. Recent surveys indicate that around 40% of the UK population is actively seeking information regarding probiotics and gut health. Public health campaigns supported by organizations such as the National Health Service (NHS) promote the significance of gut microbiomes in digestion and chronic disease prevention.


With gut-related issues affecting nearly 1 in 10 individuals in the UK, the demand for microbiome sequencing services is forecasted to escalate. This trend is further supported by Research and Development activities in the field, as companies focus on leveraging sequencing to better understand gut-health links.


Growth in Nutrition and Wellness Market


The increasing focus on nutrition and wellness is pushing the demand for microbiome sequencing services in the UK Microbiome Sequencing Services Market Industry. The UK nutritional supplements market has experienced significant growth, with emerging reports indicating a potential valuation increase of 25% over the next few years. Companies like ProbioFerm are actively pursuing microbiome sequencing to innovate and develop products that cater to these new wellness trends.


The emphasis on health-conscious living among consumers, coupled with the evolving understanding of how gut health impacts wellness, supports a strong growth trajectory for microbiome sequencing services in the UK market.


Advancements in Sequencing Technologies


Technological advancements in sequencing methods are another powerful driver for the UK Microbiome Sequencing Services Market. Organizations such as the Wellcome Sanger Institute are continuously innovating in sequencing technology, leading to lower costs and higher accuracy in microbiome analysis. Recent breakthroughs in next-generation sequencing have made microbiome analysis more accessible to clinical labs, lowering the cost by up to 40% in just a few years.


As sequencing technology becomes more efficient, researchers and healthcare professionals are expected to incorporate microbiome data into a broader range of applications, therefore underscoring the potential for market growth in the UK.


UK Microbiome Sequencing Services Market Segment Insights


Microbiome Sequencing Services Market Technology Insights


The UK Microbiome Sequencing Services Market, specifically within the Technology segment, is witnessing notable advancements driven by increasing interest in genomics and personalized medicine. This segment encompasses various approaches, such as Sequencing by Litigation (SBL), which is gaining traction due to its precision in resolving complex genetic information, thus contributing to advancements in microbial research and clinical diagnostics. Sequencing by Synthesis (SBS) showcases its robustness and cost-effectiveness, making it a preferred choice for many researchers pursuing large-scale sequencing initiatives.


With the rise of synthetic biology, Short Gun Sequencing has emerged as a powerful method to identify and characterize a wide array of microbial communities, essential for understanding their functions in health and disease.Targeted Gene Sequencing stands out as a vital technique that allows for the focused analysis of specific genes, making it particularly useful in clinical applications, where it aids in identifying disease-associated variants within microbial genomes. RNA Sequencing, known for its capacity to provide insight into gene expression and microbial interactions, plays an integral role in comprehending microbiome dynamics.


Each of these methodologies contributes significantly to the overall efficiency and accuracy of microbiome research, addressing the growing demands for more nuanced population and environmental health studies across the UK. The diversity of sequencing technologies not only ensures comprehensive analysis capabilities but also opens up a plethora of opportunities for innovation, enhancing our understanding of the complex relationships within microbial ecosystems.


Overall, the UK Microbiome Sequencing Services Market industry is positioned for robust growth, fueled by technological advancements and increased investment in health and biotechnology research, paving the way for novel applications in drug discovery, diagnostics, and therapeutic strategies.


UK Microbiome Sequencing Services Market Segment


Source: Primary Research, Secondary Research, MRFR Database, and Analyst Review


Microbiome Sequencing Services Market Application Insights


The UK Microbiome Sequencing Services Market, particularly within the Application segment, showcases diverse areas of focus, reflecting varying healthcare needs. Gastrointestinal Diseases have become increasingly significant due to the rising prevalence of disorders like irritable bowel syndrome and inflammatory bowel disease, driving demand for microbiome analysis. Infectious Diseases follow closely, with the growing threat of antibiotic-resistant pathogens making microbiome sequencing critical for understanding microbial behaviors and treatment efficacy.


In the realm of Central Nervous System (CNS) Diseases, research linking gut health to neurological conditions emphasizes the relevance of microbiome studies in developing new therapeutic options. Oncology also stands out, as understanding tumor microbiomes offers potential pathways for innovative cancer treatments. Additionally, the 'Others' category includes applications in metabolic and autoimmune disorders, providing a comprehensive overview of the sector's expansion.


Market growth in these areas is propelled by advancements in sequencing technology, increasing investment in Research and Development, and heightened awareness of microbiome roles in health, positioning the UK as a leader in microbiome research and application.


UK Microbiome Sequencing Services Market Key Players and Competitive Insights:


The UK Microbiome Sequencing Services Market is rapidly evolving, showcasing a competitive landscape driven by advancements in genomic technologies and growing awareness of the microbiome's role in human health. As research into the human microbiome expands, the demand for sequencing services has significantly increased, leading to an influx of players seeking to capitalize on this burgeoning sector. Companies in this market are focusing on innovation, expanding their service offerings, and enhancing operational efficiencies to meet the diverse needs of researchers and healthcare practitioners.


This competitive landscape is characterized by a mix of established firms and new entrants, all vying for market share in various segments, including academic research, clinical applications, and personalized medicine.uBiome has established a substantial presence in the UK Microbiome Sequencing Services Market, recognized for its pioneering efforts in microbiome research and consumer testing. The company's strength lies in its innovative approach to providing comprehensive sequencing solutions tailored to the needs of both academic institutions and private sector clients. By leveraging advanced sequencing technologies and robust bioinformatics capabilities, uBiome delivers high-quality insights into microbiome composition and functionality.


Their focus on supporting scientific research with user-friendly platforms has enabled them to build strong partnerships within the UK’s research community, further solidifying their reputation as a leader in the microbiome field.Zymo Research is another key player in the UK Microbiome Sequencing Services Market, renowned for its commitment to precision and innovation in biological research. The company’s broad portfolio includes essential products and services such as DNA/RNA extraction kits, library preparation solutions, and next-generation sequencing (NGS) services specifically tailored for microbiome analysis.


Zymo Research boasts a strong market presence backed by its rigorous quality control standards and comprehensive support for clients. The company has strategically engaged in mergers and collaborations that enhance its capabilities and offerings within the UK market, positioning itself as a trusted provider in microbiome sequencing. Through its continuous investment in research and development, Zymo Research strives to advance the understanding of the microbiome and drive innovation in applications related to health and disease.


Key Companies in the UK Microbiome Sequencing Services Market Include:



  • uBiome

  • Zymo Research

  • Macrogen

  • Ebiogen

  • Qiagen

  • Ginkgo Bioworks

  • Thermo Fisher Scientific

  • Illumina

  • Metabiota

  • BGI Group

  • Oxford Nanopore Technologies

  • Novogene

  • Genomatix

  • Aspect Biosystems

  • Enterome


UK Microbiome Sequencing Services Market Industry Developments


Recent developments in the UK Microbiome Sequencing Services Market indicate a growing interest in advanced microbial analysis technologies. Companies such as Illumina and Qiagen continue to lead innovations, focusing on integration with healthcare systems as personalized medicine gains traction. Ginkgo Bioworks has been working on scaling its biotechnology capabilities, while Thermo Fisher Scientific has launched new services that enhance sequencing efficiency. In terms of market activity, in August 2023, Novogene announced a strategic partnership with prominent UK-based institutions to enhance genomic sequencing capabilities, emphasizing the collaborative effort in advancing microbiome research.


Additionally, Enterome secured funding for its microbiome-related projects in July 2023, reflecting the increasing investments in this space. The market has seen significant valuation growth, driven primarily by demand for microbiome analysis in clinical applications and research development. In the past few years, the UK has witnessed heightened regulatory support for microbiome research, underlining its commitment to being a leader in microbial genomics education and innovation, which in turn is stimulating growth and competitive dynamics among key players in the market.


UK Microbiome Sequencing Services Market Segmentation Insights


Microbiome Sequencing Services Market Technology Outlook



  • Sequencing by Litigation (SBL)

  • Sequencing by Synthesis (SBS)

  • Short Gun Sequencing

  • Targeted Gene Sequencing

  • RNA Sequencing

  • Others


Microbiome Sequencing Services Market Application Outlook



  • Gastrointestinal Diseases

  • Infectious Diseases

  • CNS Diseases

  • Oncology

  • Others

Report Attribute/Metric Source: Details
MARKET SIZE 2018 85.17(USD Million)
MARKET SIZE 2024 93.6(USD Million)
MARKET SIZE 2035 487.32(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 16.182% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Million
KEY COMPANIES PROFILED uBiome, Zymo Research, Macrogen, Ebiogen, Qiagen, Ginkgo Bioworks, Thermo Fisher Scientific, Illumina, Metabiota, BGI Group, Oxford Nanopore Technologies, Novogene, Genomatix, Aspect Biosystems, Enterome
SEGMENTS COVERED Technology, Application
KEY MARKET OPPORTUNITIES Personalized medicine development, Agricultural microbiome analysis, Gut health optimization services, Biopharmaceutical R&D collaborations, Microbiome data analytics solutions
KEY MARKET DYNAMICS growing demand for personalized medicine, increasing prevalence of chronic diseases, advancements in sequencing technologies, rising awareness of gut health, supportive regulatory environment
COUNTRIES COVERED UK


Frequently Asked Questions (FAQ) :

The UK Microbiome Sequencing Services Market is projected to be valued at approximately 93.6 million USD in 2024.

By 2035, the market is anticipated to reach around 487.32 million USD.

The market is expected to grow at a CAGR of 16.182% from 2025 to 2035.

By 2035, the Sequencing by Synthesis (SBS) segment is expected to dominate with an estimated value of 115.5 million USD.

Key players include uBiome, Zymo Research, Macrogen, and Qiagen among others.

The Sequencing by Litigation (SBL) segment is valued at 18.0 million USD in 2024.

The Short Gun Sequencing segment is projected to be valued at 118.5 million USD by 2035.

Rising interest in personalized medicine and advancements in sequencing technologies are key growth drivers.

RNA Sequencing is valued at 12.5 million USD in the year 2024.

Challenges include regulatory hurdles and high costs associated with sequencing technologies.

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