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South America Organ-On-Chip Market Research Report By Organ Type (Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, Human-on-Chip), By Application (Drug Discovery, Toxicology Research, Others), By End-User (Pharmaceutical Companies, Research Organizations, Others) andBy Regional (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035


ID: MRFR/HC/49556-HCR | 200 Pages | Author: Rahul Gotadki| May 2025

South America Organ-On-Chip Market Overview


As per MRFR analysis, the South America Organ-On-Chip Market Size was estimated at 6.74 (USD Million) in 2023.The South America Organ-On-Chip Market Industry is expected to grow from 7.52(USD Million) in 2024 to 32.05 (USD Million) by 2035. The South America Organ-On-Chip Market CAGR (growth rate) is expected to be around 14.083% during the forecast period (2025 - 2035).


Key South America Organ-On-Chip Market Trends Highlighted


The South America Organ-On-Chip market is experiencing significant growth because of investment in biotechnology and pharmaceuticals. Government initiatives in Brazil and Argentina have been fostering new health technology innovation, which is good for organ-on-chip R&D. This growing interest is also fueled by the increasing need for alternative testing procedures that ethically go without sharpening the lion's share of animal testing, which is increasingly becoming favorable around the world. South America in particular has great untapped potential considering the collaboration between academic institutions and industries.


Local universities are beginning to work with biotech companies to design more advanced organ-on-chip models for drug screening and disease modeling. Strengthening research in South America fosters growth because they design region-specific solutions to appeal to investors and bolster technological growth. Recently, there has been an increase in attention given to personalized medicine where organ-on-chip technology is critical. Researchers from South America are putting more effort into developing region specific disease mimicking chips that would enable localized treatment and improve patient care.


Moreover, the surge of precision medicine programs in countries like Chile is fostering further investment in organ-on-chip technologies for the creation of tailored treatments. This area is also experiencing increased focus on policy regulations aimed at boosting the adoption of these technologies, which is vital for the development of clinical practice and better healthcare services in South America.


South America Organ On Chip Market size


South America Organ-On-Chip Market Drivers


Rising Demand for Personalized Medicine


The South America Organ-On-Chip Market Industry is driven by the increasing demand for personalized medicine, which has risen due to the growing prevalence of chronic diseases. According to a report from the Pan American Health Organization, chronic diseases accounted for approximately 75% of all deaths in the region in 2019. This high percentage highlights the need for innovative medical solutions like organ-on-chip technologies, which can model human organs and optimize drug testing and treatment plans.Organizations such as the Brazil's National Health Surveillance Agency (ANVISA) are pushing for regulatory frameworks that encourage the development and use of personalized medicine solutions, further propelling the growth of the market in South America.


Government Investment in Biotechnology


Government initiatives in South America focused on biotechnology and innovation are a significant driver for the South America Organ-On-Chip Market Industry. For instance, Brazil's Federal Government launched the National Bioeconomy Strategy in 2020, which allocated substantial funding towards Research and Development in biotechnological ventures. This strategy is essential for fostering advancements in organ-on-chip technologies which provide a more ethical and efficient alternative to animal testing.As more countries embrace biotechnological advancements, the market is expected to receive a considerable boost from this governmental support.


High Prevalence of Cardiovascular Diseases


The South America Organ-On-Chip Market Industry is also fueled by the high prevalence of cardiovascular diseases (CVD) in the region. According to the World Health Organization, it was estimated that over 1 million people in South America die each year from CVD, which represents approx 31% of all global deaths from such conditions. This alarming statistic has prompted healthcare organizations and researchers to invest heavily in technologies that can help in understanding and treating heart diseases effectively.Organizations such as the Argentine Society of Cardiology are advocating for innovative research, thus creating a burgeoning need for organ-on-chip platforms to simulate cardiovascular conditions for better treatment outcomes.


South America Organ-On-Chip Market Segment Insights:


Organ-On-Chip Market Organ Type Insights


The South America Organ-On-Chip Market has been gaining significant traction within the biotechnology and pharmaceutical sectors, primarily driven by its innovative approach to drug development and disease modeling. This market is segmented by Organ Type, encompassing vital components such as Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, and Human-on-Chip. Each segment plays a crucial role; for instance, the Lung-on-Chip mimics human lung physiology, serving as a critical tool for respiratory disease research and vaccine development. 


This is particularly essential given the increasing prevalence of respiratory diseases in South America, where air quality issues are prominent.The Heart-on-Chip is of particular interest due to its applications in cardiovascular disease research, which remains a leading cause of morbidity and mortality in the region. By providing a more accurate model for heart conditions, researchers can develop better-targeted therapies and assess drug safety with greater precision. The Liver-on-Chip, on the other hand, addresses the need for effective hepatotoxicity screening for drugs. 


Given the rise in liver-related ailments in South America, this segment is becoming increasingly meaningful in the context of drug development and personalized medicine.The Intestine-on-Chip reflects a growing focus on gastrointestinal disorders, which affect a considerable proportion of the population in South America, highlighting the importance of digestive health. It enables researchers to create more accurate models for studying inflammatory bowel disease and other gastrointestinal disorders, thereby promoting advancements in treatment methodologies. In the same vein, the Kidney-on-Chip caters to renal disease research, aiming to tackle the rising incidents of chronic kidney disease within the region. 


Finally, the Human-on-Chip integrates multiple organ systems, facilitating a more holistic approach to understanding human physiology and drug interactions in a microenvironment that simulates real-life conditions. This segment emphasizes the multi-organ connectivity that is vital for studying systemic diseases and comprehensive drug responses. 


The increasing reliance on these innovative platforms is primarily fueled by their potential to reduce the dependency on animal testing, thereby aligning with ethical standards and regulatory developments focused on humane and sustainable research practices. As such, the segmentation of the South America Organ-On-Chip Market by organ type underscores its role in transforming research methodologies and therapeutic development across various health domains.


South America Organ On Chip Market Segment


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Organ-On-Chip Market Application Insights


The Application segment of the South America Organ-On-Chip Market plays a crucial role in advancing biomedical and pharmaceutical research. With the growing need for efficient and ethical drug development processes, drug discovery has emerged as a leading application, enabling researchers to improve success rates and minimize failures in clinical trials. Toxicology research significantly benefits from Organ-On-Chip technology by providing more accurate predictions of human responses to toxic substances, which enhances safety assessments and regulatory compliance.Additionally, other applications within this segment address diverse areas such as personalized medicine and disease modeling. 


This diversification in applications drives the overall market growth by responding to the increasing demands for innovative solutions in healthcare. Moreover, the expansion of research initiatives in South America reflects a strong commitment to integrating cutting-edge technologies, promoting collaboration among academic institutions and biotech companies, ultimately fostering advancements in the South America Organ-On-Chip Market.As these applications evolve, they represent significant opportunities that align with global trends toward precision medicine and sustainable research practices.


Organ-On-Chip Market End-User Insights


The South America Organ-On-Chip Market has seen a notable focus on the End-User segment, which includes Pharmaceutical Companies, Research Organizations, and Others. Pharmaceutical Companies are pivotal in driving innovation, as they utilize organ-on-chip technology for drug testing, significantly reducing the time and cost associated with traditional methods. This technology allows for more biologically relevant models, enhancing the accuracy of drug efficacy and safety assessments, thereby reducing the failure rate in clinical trials. 


Research Organizations also play an essential role, leveraging organ-on-chip systems for academic and governmental studies that advance understanding of human physiology and disease modeling, reflecting the growing trend toward more personalized medicine approaches in South America.The Others category encompasses various entities, including biotechnology firms and regulatory bodies, which contribute to market vitality through collaborations, fostering innovation and research initiatives. 


The South America Organ-On-Chip Market shows promise for substantial growth, heavily influenced by these End-User segments, which address significant healthcare challenges and offer opportunities for improved regulatory compliance and faster product development. As the region continues to bolster its R&D capabilities, the demand for organ-on-chip solutions is expected to rise, benefiting the overall healthcare landscape.


Organ-On-Chip Market Regional Insights


The South America Organ-On-Chip Market is experiencing notable growth across its diverse regional landscape. Brazil leads the charge in market expansion, fueled by strong government investments in biotechnology and a robust Research and Development ecosystem. Meanwhile, Mexico is emerging as a key player, leveraging its geographical proximity to the United States and access to innovative technologies that bolster its market presence. Argentina, with its advancing biopharmaceutical sector, presents significant opportunities for the Organ-On-Chip Market, as local companies and universities increasingly focus on developing innovative solutions for medical research.


The Rest of South America is starting to adopt these technologies, highlighting a trend of increasing collaboration among nations to enhance their respective healthcare systems. This regional segmentation showcases the varying growth drivers, with factors such as healthcare needs, regulatory frameworks, and technological advancements compelling each country to prioritize advancements in organ-on-chip solutions, thereby enhancing their market dynamics and fostering competitive advantages within the industry. Overall, the South America Organ-On-Chip Market illustrates a promising outlook, with each region contributing to its trajectory through unique strengths and collaborative opportunities.


South America Organ-On-Chip Market Key Players and Competitive Insights:


The South America Organ-On-Chip Market is rapidly evolving as a significant player in the biotechnological landscape, driven by increased investments in research and development, favorable regulations, and a rising demand for innovative drug testing methods. This market is characterized by a competitive environment where various companies are striving to enhance their technological capabilities, address specific regional healthcare challenges, and cater to a growing base of customers. 


The integration of organ-on-chip technologies into research processes demonstrates vast potential for personalized medicine, toxicology testing, and disease modeling, significantly impacting the drug development pipeline. As a result, understanding the nuances of competition within this sector is crucial for stakeholders aiming to position themselves effectively in this burgeoning marketplace.Blacktrace has established a noteworthy presence in the South American Organ-On-Chip Market, leveraging its expertise in microfluidics and bioengineering to deliver state-of-the-art solutions. The company excels in developing innovative organ-on-chip platforms that replicate human organ functions accurately, facilitating advanced drug testing while reducing reliance on animal models. Blacktrace stands out for its commitment to pioneering technologies that enhance the reliability of preclinical testing, which is a vital aspect for researchers in the region focused on developing new therapeutics. 


The firm has cultivated significant partnerships with local research institutions and biopharmaceutical companies, aiming to integrate its organ-on-chip technologies into various research initiatives across South America, thereby positioning itself as a trusted entity in this competitive landscape.Mimetas has carved out a recognizable niche in the South American Organ-On-Chip Market through its comprehensive suite of organ-on-chip products and services, which target various applications in drug discovery and development. The company’s flagship products are instrumental in providing highly predictive human tissue models, enabling researchers to obtain relevant data while minimizing experimental variability. Mimetas is well-regarded for its innovative designs and application versatility, allowing clients in academia and industry to tailor solutions to their unique research needs. 


The company has been active in forging strategic alliances and partnerships to expand its market presence in South America, allowing it to access new clients and enhance its service offerings. Mimetas’ commitment to advancing organ-on-chip technology through continuous innovation and collaboration has further solidified its standing as a leader in the regional market, facilitating improvements in healthcare outcomes and fostering a more sustainable approach to drug discovery in the region.


Key Companies in the South America Organ-On-Chip Market Include:



  • Blacktrace

  • Mimetas

  • Axiogenesis

  • Biolamina

  • TissUse

  • Reinnervate

  • Kereos

  • Emulate

  • Cellasys

  • Insphero

  • Aurelia Bioscience

  • Ncardia

  • Synlogic

  • Qgel


South America Organ-On-Chip Market Industry Developments


The South America Organ-On-Chip Market has seen significant developments recently, highlighting the continued growth and innovation in this sector. The demand for advanced drug testing systems and personalized medicine is increasing, with companies like Blacktrace, Mimetas, and TissUse focusing on developing sophisticated organ models to better mimic human physiology. In August 2023, Axiogenesis announced a partnership with a major Brazilian research institution, enhancing their research capabilities within South America. Additionally, Insphero launched a new line of organ-on-chip products tailored for local markets in September 2023, signaling a commitment to fulfilling regional needs. 


Moreover, a notable acquisition occurred when Kereos acquired technology from a local startup in May 2023, aimed at improving their organ-on-chip platforms, strengthening their foothold in the region. The South American market has also experienced increased funding, with Biolamina and Aurelia Bioscience securing investments to expand their operations, thereby impacting the overall market valuation positively. In recent years, a growing interest in organ-on-chip technology, especially for its applications in toxicology and pharmaceuticals, has driven the market's valuation to exceed several million dollars, positioning it as a key area of investment and research.


South America Organ-On-Chip Market Segmentation Insights


Organ-On-Chip Market Organ Type Outlook



  • Lung-on-Chip

  • Heart-on-Chip

  • Liver-on-Chip

  • Intestine-on-Chip

  • Kidney-on-Chip

  • Human-on-Chip


Organ-On-Chip Market Application Outlook



  • Drug Discovery

  • Toxicology Research

  • Others


Organ-On-Chip Market End-User Outlook



  • Pharmaceutical Companies

  • Research Organizations

  • Others


Organ-On-Chip Market Regional Outlook



  • Brazil

  • Mexico

  • Argentina

  • Rest of South America


 

Report Scope:
Report Attribute/Metric Source: Details
MARKET SIZE 2018 6.74(USD Million)
MARKET SIZE 2024 7.52(USD Million)
MARKET SIZE 2035 32.05(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 14.083% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Million
KEY COMPANIES PROFILED Blacktrace, Mimetas, Axiogenesis, Biolamina, TissUse, Reinnervate, Kereos, Emulate, Cellasys, Insphero, Aurelia Bioscience, Ncardia, Synlogic, Qgel
SEGMENTS COVERED Organ Type, Application, End-User, Regional
KEY MARKET OPPORTUNITIES Growing pharmaceutical research investments, Increasing demand for personalized medicine, Rising prevalence of chronic diseases, Advancements in biotechnology innovation, Government support for research initiatives
KEY MARKET DYNAMICS Rising demand for personalized medicine, Increased investment in biotechnology, Government support for research initiatives, Advancements in microfluidics technology, Growing focus on drug testing alternatives
COUNTRIES COVERED Brazil, Mexico, Argentina, Rest of South America


Frequently Asked Questions (FAQ) :

The South America Organ-On-Chip Market is expected to be valued at 7.52 million USD in 2024.

By 2035, the market is anticipated to reach a value of 32.05 million USD.

The market is expected to grow at a CAGR of 14.083% from 2025 to 2035.

Brazil is expected to hold the largest market share, valued at 2.5 million USD in 2024.

Major players include Blacktrace, Mimetas, Axiogenesis, Biolamina, TissUse, and Emulate among others.

The Lung-on-Chip segment is valued at 1.5 million USD in 2024 and is projected to reach 6.39 million USD in 2035.

The Kidney-on-Chip segment is expected to grow from 1.0 million USD in 2024 to 4.14 million USD in 2035.

The Intestine-on-Chip segment is projected to reach 7.33 million USD by 2035.

There are significant opportunities for growth due to advancements in personalized medicine and drug testing applications.

Argentina's market for Organ-On-Chip is valued at 1.2 million USD in 2024 and is expected to grow to 5.1 million USD by 2035.

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