Protein Engineering Market Research Report - Forecast till 2032

Protein Engineering Market Research Report Information By Type (Instrument, Reagent, and Services & Software), By Application (Food & Detergent Industries, Environment, Medical, Biopolymer Production, and Nano Biotechnology), By Method (Rational Protein Design, Directed, and Evolution), By End User (Pharmaceutical & Biotechnology Companies, Contract Engineering Organizations, and Academic Research Institutes), and By Region (North America, Europe, Asia-Pacific, and Rest Of The World) โ€“Market Forecast Till 2032

ID: MRFR/HC/0220-CR | 132 Pages | Author: Kinjoll Dey | September 2021         

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Global Protein Engineering Market Overview


The Protein Engineering Market Size was valued at USD 1.5 Billion in 2022 and is projected to grow from USD 1.7 Billion in 2023 to USD 4.09 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 11.80% during the forecast period (2023 - 2032). Chronic diseases are becoming more prevalent, and synthetic biology is receiving more funding, which are the key market drivers enhancing market growth.
Protein Engineering Market


Source Secondary Research, Primary Research, MRFR Database, and Analyst Review


Protein Engineering Market Trends



  • Increasing demand for treatments and medications based on proteins drives market growth


Market CAGR for protein engineering is being driven by the rising need for treatments and medications based on proteins over the forecast period, and market for protein engineering, which is extremely dependent on the rising need for proteins made from proteins. Biologics, or proteins-based medications, treat various illnesses like cancer, autoimmune conditions, and uncommon genetic disorders. Drugs based on proteins have several benefits over conventional small-molecule medications. As they are created to interact with particular targets in the body, they are frequently more selective and have fewer adverse effects.


Additionally, protein-based medications have a lower likelihood of being metabolized by the liver, which can increase their effectiveness and lower the possibility of toxicity. These benefits have led to a huge increase in the demand for protein-based medicines on the international market. Many variables, such as the rising prevalence of chronic diseases, aging populations, and rising healthcare costs, influence this rise. The desire for new and improved therapeutics is mostly driven by the increased prevalence of chronic diseases like cancer, diabetes, and cardiovascular problems.


In addition, it is projected that the market would grow significantly as a result of the rising number of government programmes meant to advance the field of protein engineering. As a result, there has been a growth in this field's R&D spending, amount of funds awarded, and research and development programs. For instance, Nabla Bio reported that a USD 11 million seed fundraising round would be completed in December 2021. With the aid of this funding, a platform for AI-first design will be created, paving the way for new antibody therapies.


Likewise, Generate Biomedicines, and Amgen confirmed A research partnership agreement to create protein therapeutics for 5 clinical targets in January 2022. The demand for protein engineering is being driven by the rise in chronic & lifestyle diseases like diabetes, cardiovascular disorders, and others. As a result, it is anticipated that the demand for protein engineering will increase throughout the projection period due to the high demand for treatments and medications. Thus, driving the protein engineering market revenue.


Protein Engineering Market Segment Insights


Protein Engineering Type Insights


The market segments of protein engineering, based on type, includes instruments, reagents, and services & software. The instrumentS segment dominated the market, accounting for 51.50% of market revenue (0.77 Billion). Demand for this market segment is being driven by the growing preference among researchers for automated methods for encouraging quick molecular development processes.


Protein Engineering Application Insights


The protein engineering market segmentation, based on application, includes food & detergent Industries, environment, medical, biopolymer production, and nanobiotechnology. The nanobiotechnology category generated the most income (35%). This is due to the widespread use of hybrid techniques, which combine directed evolution and rational design, for various purposes, such as improving redox proteins and enzymes. The fabrication of nano-devices for biosensing and other significant nanotechnology engineering applications places a high value on these enzymes, boosting the chances for future growth.


Protein Engineering Route Administration Insights


The market segmentation of protein engineering, based on method, includes rational protein design and directed evolution. The rational protein design segment dominated the market, accounting for 58% of market revenue. The technology's vast application in enzyme engineering and antibody development accounts for the dominant share. Enzyme engineering has seen a tremendous increase in its commercial uses, which has led to the creation of improved and modified enzymes with the appropriate catalytic capabilities.


Protein Engineering End User Insights


The  protein engineering market segmentation, based on end-users, includes pharmaceuticals & biotechnology companies, contract engineering organizations, and academic research institutes. The pharmaceuticals & biotechnology companies segment dominated the market, accounting for 52% of market revenue. The segment is expanding due to more and more in silico drug discovery models being used to treat neurological issues, cancer, and diabetes. These companies continuously attempt to preserve their market position by creating drug versions of patent-expiring pharmaceuticals utilizing a computer modeling technique.


Figure 1  Protein Engineering Market by End User, 2022 & 2032 (USD Billion)


Source Secondary Research, Primary Research, MRFR Database, and Analyst Review


Protein Engineering Regional Insights


By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American protein engineering market will dominate this market, owing to the presence of numerous market players and their varied strategic efforts.


Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2  PROTEIN ENGINEERING MARKET SHARE BY REGION 2022 (USD Billion)


Source Secondary Research, Primary Research, MRFR Database, and Analyst Review


Europe's Protein Engineering market accounts for the second-largest market share due to the availability of a sizable population base for the development and clinical testing of protein engineering applications. Further, the German market of protein engineering held the largest market share, and the UK market of protein engineering was the second-largest growing market in the European region.


The Asia-Pacific protein engineering market is expected to grow at the fastest CAGR from 2023 to 2032. This is due to the high prevalence of autoimmune, cardiovascular, and cancer diseases in developing Asian nations. Due to the significant economic development in emerging countries like India and China, unexplored potential in this region is also anticipated to help the sector thrive. Moreover, China’s market of protein engineering held the largest market share, and the Indian market of protein engineering was the fastest-growing market in the Asia-Pacific region.


Protein Engineering Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development to expand their product lines, which will help the market of protein engineering, grow even more. Market participants are also engaging in a variety of strategic measures in order to grow their businesses  presence, with significant market development such as new product releases, contractual agreements, mergers and acquisitions, increased investments, and so on partnerships with other organisations. The protein engineering industry must offer cost-effective items to expand and survive in a more competitive and developing market condition.


One of the most important company strategies is to manufacture locally to save operational costs. manufacturers use in the  protein engineering industry to benefit clients and increase the market sector. In recent years, the protein engineering industry has provided some of the greatest significant benefits to medicine. Major players in the protein engineering market, including Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).


Agilent Technologies, Inc. offers fundamental bio-analytical and electronic measurement solutions to the chemical analysis, communications, electronics, and life sciences industries. The business provides semiconductor and board testing and electronic and bioanalytical measurements. In October 2020, The Agilent Seahorse XFp Analyzer, a device for assessing metabolic activity in living cells that can be utilized in protein engineering research, was introduced by Agilent Technologies.


AbbVie Inc. researches and develops pharmaceutical products. The company produces pharmaceutical medications for specialized treatment fields like immunology, chronic renal disease, hepatitis C, women's health, oncology, and neuroscience. Multiple sclerosis, Parkinson's, and Alzheimer's disease are just a few of the illnesses that AbbVie treats. In March 2022, for treating moderately to highly active ulcerative colitis, the U.S. FDA gave AbbVie Inc. permission to use RINVOQ (upadacitinib), a new medication.


Key Companies in the market of Protein Engineering include



Protein Engineering Industry Developments


January 2021:A research partnership between Amgen and Generate Biomedicines was announced to identify and develop protein therapies for five clinical targets across various therapeutic domains and delivery systems.


December 2021:A major provider of software for biopharmaceutical protein characterization and proteomics analysis, Protein Metrics, Inc., was acquired by Insightful Science, a software firm that enables the cloud for scientific discovery. By extending the Company's R&D value chain, the purchase opens up the biopharmaceutical protein analysis market and removes data analysis bottlenecks currently connected to extensive protein research.


February 2022:The Tierra Protein Platform, an e-commerce platform that enables customers to obtain distinctive protein engineering items made, verified, and delivered to them in only a few clicks, was introduced by Tierra Biosciences.


Protein Engineering Market Segmentation


Protein Engineering Type Outlook



  • Instrument

  • Reagent

  • Services & Software


Protein Engineering Application Outlook



  • Food & Detergent Industries

  • Environment

  • Medical

  • Biopolymer Production

  • Nano Biotechnology


Protein Engineering Method Outlook



  • Rational Protein Design

  • Directed Evolution


Protein Engineering End User Outlook



  • Pharmaceutical & Biotechnology Companies

  • Contract Engineering Organizations

  • Academic Research Institutes


Protein Engineering Regional Outlook



  • North America

    • US

    • Canada



  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe



  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific



  • Rest of the World

    • Middle East

    • Africa

    • Latin America



Report Scope:

Report Attribute/Metric Details
Market Size 2022 USD 1.5 Billion
Market Size 2023 USD 1.7 Billion
Market Size 2032 USD 4.09 Billion
Compound Annual Growth Rate (CAGR) 11.80% (2023-2032)
Base Year 2022
Market Forecast Period 2023-2032
Historical Data 2018- 2022
Market Forecast Units Value (USD Billion)
Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered Type, Application, Method, End User, and Region
Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
Countries Covered The US, Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S)
Key Market Opportunities Developing protein engineering markets
Key Market Dynamics Rising incidence of chronic illnessesGrowing financial support for synthetic biology




Frequently Asked Questions (FAQ) :

The  protein engineering market size was valued at USD 1.5 Billion in 2022.

The  market is projected to grow at a CAGR of 11.80% during the forecast period, 2023-2032.

The key players in the market are AB-Sciex (U.S.), Agilent Technologies (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).

The instrument category dominated the market in 2022.

The nanobiotechnology category dominated the market in 2022.

The rational protein design category dominated the market in 2022.

Pharmaceutical & biotechnology companies had the largest share of the market.

Key Questions Answered

  • Global Market Outlook
  • In-depth analysis of global and regional trends
  • Analyze and identify the major players in the market, their market share, key developments, etc.
  • To understand the capability of the major players based on products offered, financials, and strategies.
  • Identify disrupting products, companies, and trends.
  • To identify opportunities in the market.
  • Analyze the key challenges in the market.
  • Analyze the regional penetration of players, products, and services in the market.
  • Comparison of major playersโ€™ financial performance.
  • Evaluate strategies adopted by major players.
  • Recommendations
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