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    Necrotising Enterocolitis Market

    ID: MRFR/Pharma/4541-HCR
    100 Pages
    Rahul Gotadki
    October 2025

    Necrotising Enterocolitis Market Research Report Information By End-User (Hospitals, Surgical and Ablation Centers, Research Institute and Others), By Treatment (Total Parenteral Nutrition (TPN), Gastrointestinal Decompression, Antimicrobial Therapy, Antifungal Treatment, Paracentesis and Others), By Distribution (Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy and Others), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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    Necrotising Enterocolitis Market Infographic

    Necrotising Enterocolitis Market Summary

    As per Market Research Future Analysis, the Necrotising Enterocolitis Market was valued at 5.44 USD Billion in 2024 and is projected to grow to 9.81 USD Billion by 2035, with a CAGR of approximately 5.50% from 2025 to 2035. The market is driven by the rising incidence of necrotising enterocolitis, improved access to antibiotic medications, and a supportive regulatory environment. The increasing R&D efforts and government funding for healthcare initiatives are expected to further enhance market growth. Hospitals are the primary end-users, while Total Parenteral Nutrition (TPN) is the leading treatment segment. North America is anticipated to dominate the market due to advanced disease detection technologies and high healthcare spending.

    Key Market Trends & Highlights

    The necrotising enterocolitis market is witnessing significant growth driven by various factors.

    • Market Size in 2024: 5.44 USD Billion; Expected to reach 9.81 USD Billion by 2035.
    • CAGR from 2025 to 2035: Approximately 5.50%.
    • Rising incidence of NEC: 1-3 cases per 1,000 live births annually in North America.
    • Hospitals segment dominates due to increased NEC cases and early detection awareness.

    Market Size & Forecast

    2024 Market Size USD 5.44 Billion
    2035 Market Size USD 9.81 Billion
    CAGR (2025-2035) 5.50%

    Major Players

    Key players include Abbott Laboratories Inc., Astellas Pharma Inc., Bayer HealthCare AG, Becton, Dickinson, and Company, Bristol-Myers Squibb Company, Daiichi Sankyo Company, Ltd., Eli Lilly and Co., Enzon Pharmaceuticals, Inc., Hoffmann-La Roche Ltd, GI Supply, and GlaxoSmithKline Plc.

    Necrotising Enterocolitis Market Trends

    Rising incidence for NEC is driving the market growth

    The market CAGR is being driven by the rising occurrence of necrotizing enterocolitis. When the intestinal inflammation known as necrotizing enterocolitis, which typically affects the colon, is not properly treated, it can be fatal. A hole forms in the intestinal wall as a result of necrotizing enterocolitis, which only affects the intestinal lining. Since the break in the intestinal wall allows the normal bacteria in the gut to spill into the belly, other surrounding body organs become infected. A medical emergency has been created by the infection's rapid progression.

    The most prevalent time for NEC to afflict newborns is 3 to 12 days following birth. Lethargy, fever, apnea, poor tolerance to emotions, bloody stool, stomach redness, and others are among the signs of NEC. Antibiotics, vasopressors, glucocorticoids, and opioid analgesics are some of the most popular treatments for NEC. According to an NCBI publication, NEC is the most common cause of newborn gastrointestinal infection-related death, accounting for 1-3 occurrences per 1000 live births annually in North America.

    This growing patient population has a variety of symptoms that call for appropriate treatment; as a result, it is anticipated that the market will experience profitable expansion.

    The market expansion is predicted to be fueled by the expanded range of treatment options available for NEC. Increasing populations and per capita incomes have changed people's needs, which is fueling the  market's revenue growth. People now prefer more cutting-edge, scientifically complex treatments and pharmaceuticals. The government's improved regulatory framework for the development of new antibiotics and therapies to minimize the effects of necrotizing enterocolitis in newborn babies, as well as the accessibility of treatments and medications for the treatment of necrotizing enterocolitis, are also expected to significantly propel revenue growth of the necrotizing enterocolitis market over the forecast period.

    The rising incidence of necrotising enterocolitis among preterm infants underscores the urgent need for enhanced clinical strategies and innovative therapeutic approaches to mitigate this life-threatening condition.

    Centers for Disease Control and Prevention (CDC)

    Necrotising Enterocolitis Market Drivers

    Market Growth Projections

    The Global Necrotising Enterocolitis Market Industry is poised for substantial growth, with projections indicating a market value of 9.81 USD Billion by 2035. This growth is underpinned by various factors, including advancements in medical technology, increased awareness, and government support. The compound annual growth rate of 5.51% from 2025 to 2035 suggests a robust expansion trajectory. As healthcare systems worldwide continue to prioritize neonatal health, the demand for effective treatments and interventions for necrotising enterocolitis is likely to rise. This positive outlook reflects the industry's potential to address the challenges associated with this serious condition.

    Increased Awareness and Education

    There is a growing awareness regarding necrotising enterocolitis among healthcare professionals and parents, which is positively influencing the Global Necrotising Enterocolitis Market Industry. Educational initiatives aimed at informing caregivers about the signs, symptoms, and risk factors associated with this condition are crucial. Enhanced understanding leads to earlier diagnosis and intervention, which can significantly improve survival rates. As awareness campaigns proliferate, the demand for diagnostic and therapeutic solutions is expected to rise. This trend is reflected in the anticipated market growth, with projections indicating a value of 9.81 USD Billion by 2035, highlighting the impact of education on healthcare outcomes.

    Advancements in Medical Technology

    Technological advancements in neonatal care are playing a crucial role in the Global Necrotising Enterocolitis Market Industry. Innovations such as improved imaging techniques, minimally invasive surgical procedures, and enhanced nutritional support systems are contributing to better outcomes for affected infants. These advancements not only facilitate early diagnosis but also enhance treatment efficacy, thereby reducing mortality rates associated with necrotising enterocolitis. As healthcare providers adopt these technologies, the market is likely to expand, with a projected compound annual growth rate of 5.51% from 2025 to 2035. This growth trajectory underscores the importance of continuous innovation in improving neonatal health.

    Government Initiatives and Funding

    Government initiatives aimed at improving neonatal health are significantly impacting the Global Necrotising Enterocolitis Market Industry. Various countries are implementing policies to enhance healthcare infrastructure, particularly in neonatal intensive care units. Increased funding for research and development of new treatments and technologies is also evident. These initiatives not only aim to reduce the incidence of necrotising enterocolitis but also to improve overall neonatal care. As governments prioritize infant health, the market is likely to benefit from increased investments, fostering innovation and expanding access to effective treatments. This supportive environment is crucial for achieving sustainable growth in the industry.

    Rising Incidence of Premature Births

    The Global Necrotising Enterocolitis Market Industry is witnessing an increase in demand due to the rising incidence of premature births. According to health statistics, approximately 15 million infants are born prematurely each year, which significantly elevates the risk of developing necrotising enterocolitis. This condition predominantly affects preterm infants, leading to a higher need for specialized medical interventions and treatments. As the global population continues to grow, the number of premature births is expected to rise, thereby driving the market's growth. The projected market value of 5.44 USD Billion in 2024 reflects this increasing demand for effective management and treatment options.

    Growing Demand for Nutritional Products

    The demand for specialized nutritional products designed for preterm infants is a significant driver of the Global Necrotising Enterocolitis Market Industry. Nutritional support plays a vital role in the prevention and management of necrotising enterocolitis, as appropriate feeding practices can mitigate risks. The market for these nutritional products is expanding, driven by the need for tailored solutions that cater to the unique requirements of vulnerable infants. As healthcare providers increasingly recognize the importance of nutrition in neonatal care, the market is expected to grow substantially, contributing to the overall projected market value of 5.44 USD Billion in 2024.

    Market Segment Insights

    Necrotising Enterocolitis End-User Insights

    The necrotising enterocolitis market segmentation, based on end-user includes Hospitals, Surgical and Ablation Centers, Research Institute and Others. The hospitals segment dominated the market. due to an increase in NEC cases and growing knowledge of early detection. In addition, hospitals are now regarded as primary care institutions by the majority of patients, which is expected to substantially increase demand in the near future. Whereas, during the projection period, research institute segment is anticipated to increase at the greatest CAGR. The prevalence of necrotizing enterocolitis is rising, and there are more research institutes than ever before.

    Because these institutes aids in the early detection of the disease.

    Necrotising Enterocolitis Treatment Insights

    The necrotising enterocolitis market segmentation, based on treatment includes Total Parenteral Nutrition (TPN), Gastrointestinal Decompression, Antimicrobial Therapy, Antifungal Treatment, Paracentesis and Others. The total parenteral nutrition (TPN) segment dominated the market. Total parenteral nutrition (TPN), which delivers nutrients intravenously, may initially be necessary for infants with NEC. Enteral feeding, or feeding through the digestive tract, is progressively resumed when the condition gets better. Since breast milk has been proved to protect against NEC, it is preferable. Prebiotics or probiotics may occasionally be used to support gut health.

    Necrotising Enterocolitis Distribution Insights

    The necrotising enterocolitis market segmentation, based on distribution, includes Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy and Others. The hospital pharmacy category generated the most income. Necrotizing enterocolitis (NEC) is managed and treated by the hospital pharmacy segment, which supplies drugs such antibiotics and other supportive medicines. The pharmacy department is in charge of locating, preparing, and dispensing the medicines required for treating NEC patients even if there isn't a designated "market" for NEC inside hospital pharmacies.

    Figure 1  Necrotising Enterocolitis Market, by Distribution, 2022 & 2032 (USD Billion)

    Source Secondary Research, Primary Research, MRFR Database and Analyst Review

    Get more detailed insights about Necrotising Enterocolitis Market

    Regional Insights

    By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North American necrotising enterocolitis market area will dominate this market because necrotizing enterocolitis is becoming more common and because disease detection technology is advanced. Necrotizing enterocolitis, with 1-3 cases per 1,000 births observed in North America each year, is the leading cause of gastrointestinal infection-related infant death, according to the National Centre for Biotechnology Information (NCBI). The expanding patient base has a variety of symptoms that call for the right care, which is expected to fuel market growth.

    The North American market is also being driven by an increase in healthcare spending. Over the course of the projected period, these factors are also anticipated to help the region gain market share.

    Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 2 NECROTISING ENTEROCOLITIS MARKET SHARE BY REGION 2022 (USD Billion)NECROTISING ENTEROCOLITIS MARKET SHARE BY REGION 2022

    Source Secondary Research, Primary Research, MRFR Database and Analyst Review

    Europe necrotising enterocolitis market accounts for the second-largest market share as the majority of the research and development efforts are being made in industrialized nations like France, Germany, Denmark, Belgium, etc., for the creation of a long-lasting remedy for the infection. Additionally, these nations have seen a significant expansion of the necrotizing enterocolitis market as a result of the quick advancements in technology. Further, the German necrotising enterocolitis market held the largest market share, and the UK necrotising enterocolitis market was the fastest growing market in the European region

    The Asia-Pacific Necrotising enterocolitis Market is expected to grow at the fastest CAGR from 2023 to 2032. Numerous nations, including China, Japan, Korea, and India, are thought to produce the majority of the market's earnings from necrotizing enterocolitis. Data on necrotizing enterocolitis show that the majority of people in these nations are infants and newborns, who are more prone to developing necrotizing enterocolitis. Additionally, the region's healthcare market is experiencing revenue growth as a result of the shift in people's health consciousness and the modernization of healthcare facilities.

    Moreover, China’s necrotising enterocolitis market held the largest market share, and the Indian necrotising enterocolitis market was the fastest growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    Leading market players are investing heavily in research and development in order to expand their product lines, which will help the necrotising enterocolitis market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their  footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, necrotising enterocolitis industry must offer cost-effective items.

    Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the  necrotising enterocolitis industry to benefit clients and increase the market sector. In recent years, the necrotising enterocolitis industry has offered some of the most significant advantages to market.

    Major players in the necrotising enterocolitis market attempting to increase market demand by investing in research and development operations include Abbott Laboratories Inc. (U.S.), Astellas Pharma Inc. (Japan), Bayer HealthCare AG (Germany), Becton, Dickinson, and Company (BD) (U.S.), Bristol-Myers Squibb Company (U.S.), Daiichi Sankyo Company, Ltd. (Japan), Eli Lilly and Co. (U.S.), Enzon Pharmaceuticals, Inc. (U.S.), Hoffmann-La Roche Ltd (Switzerland), GI Supply (U.S.), and GlaxoSmithKline Plc (UK).

    Bristol-Myers Squibb Co. (BMS) is a specialist biopharmaceutical business that develops, manufactures, distributes, and sells drugs and related medical supplies to people with serious conditions. Cancer, cardiovascular, immunology, and fibrotic therapeutic projects are its main areas of interest. The business provides its goods to wholesalers, retail pharmacies, health care workers, hospitals, and governmental organisations all around the world. Products from BMS are available in the US, Europe, and Japan. The organisation conducts research with a focus on the discovery and development of brand-new medications that treat severe illnesses in regions with a high unmet medical need.

    Pharmaceuticals of all kinds are discovered, developed, produced, and sold by Astellas Pharma Inc (Astellas). Marketed treatments for the treatment of a variety of urological disorders, cancer, nephrology, infectious diseases, metabolic diseases, immunodeficiency diseases, and transplantation are included in the company's product portfolio. Its pipeline includes drug candidates for the treatment of various diseases, including acute myeloid leukaemia (AML), urothelial cancer, gastric cancer, gastroesophageal junction cancer, anaemia linked to chronic kidney disease (CKD) in dialysis patients, rheumatoid arthritis, and non-dialysis patients.

    Key Companies in the Necrotising Enterocolitis Market market include

    Industry Developments

    June 2022 The Exclusive Human Milk Diet, which includes Prolacta Bioscience products (Prolacta's EHMD), has been used in the neonatal intensive care unit (NICU) with the first evidence-based feeding approach just being introduced by Prolacta Bioscience. The EHMD Protocol TM from Prolacta is the first nutritional recommendation for the use of the company's human milk-based nutritional products, and it addresses the nutritional issues of delayed and inadequate sustenance presented by low birth weight preterm newborns.

    February 2021 Through the enrollment of 300 preterm children in the ongoing clinical Phase III research of IBP-9414, Infant Bacterial Therapeutics (IBT) achieved a significant milestone. In order to enroll children with extremely low birth weights, this means that a safety investigation of these newborns will be carried out. It is anticipated that this will significantly increase recruitment rates. It is anticipated that the investigation will be finished by November 2022. The expansion of the  market may be significantly impacted by this study's success.

    March 2018 Prometic Life Sciences Inc.'s Inter-Alpha-Inhibitor-Proteins, which is anticipated to be a major medication for the treatment of necrotizing enterocolitis, received approval from the U.S. Food and Drug Administration (FDA) department.

    Future Outlook

    Necrotising Enterocolitis Market Future Outlook

    The Global Necrotising Enterocolitis Market is projected to grow at a 5.50% CAGR from 2025 to 2035, driven by advancements in neonatal care, increased awareness, and innovative treatment options.

    New opportunities lie in:

    • Develop targeted therapies focusing on early-stage NEC detection and management. Invest in telemedicine solutions for remote monitoring of at-risk infants. Enhance partnerships with hospitals for integrated care pathways and clinical trials.

    By 2035, the market is expected to demonstrate robust growth, reflecting advancements in treatment and increased healthcare investments.

    Market Segmentation

    Necrotising Enterocolitis End-User Outlook (USD Billion, 2018-2032)

    • Hospitals
    • Surgical and Ablation Centers
    • Research Institute
    • Others

    Necrotising Enterocolitis Regional Outlook (USD Billion, 2018-2032)

    • {"North America"=>["US"
    • "Canada"]}
    • {"Europe"=>["Germany"
    • "France"
    • "UK"
    • "Italy"
    • "Spain"
    • "Rest of Europe"]}
    • {"Asia-Pacific"=>["China"
    • "Japan"
    • "India"
    • "Australia"
    • "South Korea"
    • "Rest of Asia-Pacific"]}
    • {"Rest of the World"=>["Middle East"
    • "Africa"
    • "Latin America"]}

    Necrotising Enterocolitis Treatment Outlook (USD Billion, 2018-2032)

    • Total Parenteral Nutrition (TPN)
    • Gastrointestinal Decompression
    • Antimicrobial Therapy
    • Antifungal Treatment
    • Paracentesis
    • Others

    Necrotising Enterocolitis Distribution Outlook (USD Billion, 2018-2032)

    • Direct Tender
    • Hospital Pharmacy
    • Retail Pharmacy
    • Online Pharmacy
    • Others

    Report Scope

    Report Attribute/MetricDetails
    Market Size 2024   5.44 (USD Billion)
    Market Size 2025   5.74 (USD Billion)
    Market Size 20359.81 (USD Billion)
    Compound Annual Growth Rate (CAGR)5.50% (2025 - 2035)
    Report CoverageRevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year2024
    Market Forecast Period2025 - 2035
    Historical Data2020 - 2024
    Report CoverageRevenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments CoveredEnd-User, Treatment, Distribution and Region
    Geographies CoveredNorth America, Europe, Asia Pacific, and the Rest of the World
    Countries CoveredThe US, Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies ProfiledAbbott Laboratories Inc. (U.S.), Astellas Pharma Inc. (Japan), Bayer HealthCare AG (Germany), Becton, Dickinson, and Company (BD) (U.S.), Bristol-Myers Squibb Company (U.S.), Daiichi Sankyo Company, Ltd. (Japan), Eli Lilly and Co. (U.S.), Enzon Pharmaceuticals, Inc. (U.S.), Hoffmann-La Roche Ltd (Switzerland), GI Supply (U.S.), and GlaxoSmithKline Plc (UK)
    Key Market OpportunitiesNew product launches and R&D amongst major key players
    Key Market DynamicsThere have been continuous improvements in the treatment of necrotizing enterocolitis ly

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the projected growth of the Necrotising Enterocolitis market?

    The Necrotising Enterocolitis market is the expected increase in total market value of 9.81 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Necrotising Enterocolitis market?

    Necrotising Enterocolitis market size was valued at approximately 5.44 billion USD in 2024. This figure will reach 9.81 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Necrotising Enterocolitis market?

    Necrotising Enterocolitis market is expected to grow at a CAGR of 5.5% between 2025 and 2035.

    How much will the Necrotising Enterocolitis market be worth by 2035?

    Necrotising Enterocolitis market is expected to be worth of 9.81 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Necrotising Enterocolitis market perform over the next 10 years?

    Over the next 10 years the Necrotising Enterocolitis market is expected to shift from usd billion 5.44 to 9.81 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region held the largest market share in the necrotising enterocolitis market?

    North America had the largest share in the market.

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