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Necrotising Enterocolitis Market

ID: MRFR/Pharma/4541-HCR
100 Pages
Rahul Gotadki
October 2025

Necrotising Enterocolitis Market Research Report Information By End-User (Hospitals, Surgical and Ablation Centers, Research Institute and Others), By Treatment (Total Parenteral Nutrition (TPN), Gastrointestinal Decompression, Antimicrobial Therapy, Antifungal Treatment, Paracentesis and Others), By Distribution (Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy and Others), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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Necrotising Enterocolitis Market Summary

As per MRFR analysis, the Necrotising Enterocolitis Market Size was estimated at 5.44 USD Billion in 2024. The Necrotising Enterocolitis industry is projected to grow from 5.74 USD Billion in 2025 to 9.81 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.5 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Necrotising Enterocolitis Market is poised for growth driven by increasing awareness and innovative treatment strategies.

  • North America remains the largest market for necrotising enterocolitis, reflecting a robust healthcare infrastructure and advanced medical technologies.
  • The Asia-Pacific region is emerging as the fastest-growing market, driven by rising healthcare expenditures and increasing awareness of neonatal health.
  • Premature infants constitute the largest segment, highlighting the critical need for effective interventions in this vulnerable population.
  • The increasing incidence of necrotising enterocolitis and advancements in medical technology are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 5.44 (USD Billion)
2035 Market Size 9.81 (USD Billion)
CAGR (2025 - 2035) 5.5%

Major Players

AbbVie Inc (US), AstraZeneca PLC (GB), Baxter International Inc (US), Fresenius Kabi AG (DE), MediWound Ltd (IL), Pediatric Bioscience LLC (US), Sobi AB (SE), Takeda Pharmaceutical Company Limited (JP)

Necrotising Enterocolitis Market Trends

The Necrotising Enterocolitis Market is currently experiencing a notable evolution, driven by a combination of increasing awareness regarding neonatal health and advancements in medical technology. The rising incidence of this serious gastrointestinal condition among premature infants has prompted healthcare providers to seek innovative treatment options. As a result, there is a growing emphasis on research and development, leading to the introduction of novel therapies and improved diagnostic tools. This shift appears to be fostering a more proactive approach to managing necrotising enterocolitis, which may ultimately enhance patient outcomes. Moreover, the landscape of the Necrotising Enterocolitis Market is influenced by collaborative efforts among various stakeholders, including healthcare professionals, researchers, and pharmaceutical companies. These collaborations seem to facilitate the sharing of knowledge and resources, thereby accelerating the development of effective interventions. Additionally, the increasing focus on preventive measures, such as nutritional support and early detection strategies, indicates a potential shift towards a more comprehensive management framework. As the market continues to evolve, it is likely that these trends will shape the future of necrotising enterocolitis care, ultimately benefiting vulnerable populations such as premature infants.

Rising Awareness and Education

There is a growing emphasis on educating healthcare professionals and parents about necrotising enterocolitis. This trend appears to enhance early detection and intervention, potentially reducing the severity of the condition.

Innovative Treatment Approaches

The Necrotising Enterocolitis Market is witnessing the emergence of novel therapies and treatment modalities. These innovations may improve patient outcomes and offer new hope for affected infants.

Collaborative Research Initiatives

Increased collaboration among researchers, healthcare providers, and pharmaceutical companies is evident. This trend suggests a concerted effort to advance understanding and treatment of necrotising enterocolitis.

Necrotising Enterocolitis Market Drivers

Market Growth Projections

The Global Necrotising Enterocolitis Market Industry is poised for substantial growth, with projections indicating a market value of 9.81 USD Billion by 2035. This growth is underpinned by various factors, including advancements in medical technology, increased awareness, and government support. The compound annual growth rate of 5.51% from 2025 to 2035 suggests a robust expansion trajectory. As healthcare systems worldwide continue to prioritize neonatal health, the demand for effective treatments and interventions for necrotising enterocolitis is likely to rise. This positive outlook reflects the industry's potential to address the challenges associated with this serious condition.

Increased Awareness and Education

There is a growing awareness regarding necrotising enterocolitis among healthcare professionals and parents, which is positively influencing the Global Necrotising Enterocolitis Market Industry. Educational initiatives aimed at informing caregivers about the signs, symptoms, and risk factors associated with this condition are crucial. Enhanced understanding leads to earlier diagnosis and intervention, which can significantly improve survival rates. As awareness campaigns proliferate, the demand for diagnostic and therapeutic solutions is expected to rise. This trend is reflected in the anticipated market growth, with projections indicating a value of 9.81 USD Billion by 2035, highlighting the impact of education on healthcare outcomes.

Advancements in Medical Technology

Technological advancements in neonatal care are playing a crucial role in the Global Necrotising Enterocolitis Market Industry. Innovations such as improved imaging techniques, minimally invasive surgical procedures, and enhanced nutritional support systems are contributing to better outcomes for affected infants. These advancements not only facilitate early diagnosis but also enhance treatment efficacy, thereby reducing mortality rates associated with necrotising enterocolitis. As healthcare providers adopt these technologies, the market is likely to expand, with a projected compound annual growth rate of 5.51% from 2025 to 2035. This growth trajectory underscores the importance of continuous innovation in improving neonatal health.

Government Initiatives and Funding

Government initiatives aimed at improving neonatal health are significantly impacting the Global Necrotising Enterocolitis Market Industry. Various countries are implementing policies to enhance healthcare infrastructure, particularly in neonatal intensive care units. Increased funding for research and development of new treatments and technologies is also evident. These initiatives not only aim to reduce the incidence of necrotising enterocolitis but also to improve overall neonatal care. As governments prioritize infant health, the market is likely to benefit from increased investments, fostering innovation and expanding access to effective treatments. This supportive environment is crucial for achieving sustainable growth in the industry.

Rising Incidence of Premature Births

The Global Necrotising Enterocolitis Market Industry is witnessing an increase in demand due to the rising incidence of premature births. According to health statistics, approximately 15 million infants are born prematurely each year, which significantly elevates the risk of developing necrotising enterocolitis. This condition predominantly affects preterm infants, leading to a higher need for specialized medical interventions and treatments. As the global population continues to grow, the number of premature births is expected to rise, thereby driving the market's growth. The projected market value of 5.44 USD Billion in 2024 reflects this increasing demand for effective management and treatment options.

Growing Demand for Nutritional Products

The demand for specialized nutritional products designed for preterm infants is a significant driver of the Global Necrotising Enterocolitis Market Industry. Nutritional support plays a vital role in the prevention and management of necrotising enterocolitis, as appropriate feeding practices can mitigate risks. The market for these nutritional products is expanding, driven by the need for tailored solutions that cater to the unique requirements of vulnerable infants. As healthcare providers increasingly recognize the importance of nutrition in neonatal care, the market is expected to grow substantially, contributing to the overall projected market value of 5.44 USD Billion in 2024.

Market Segment Insights

By Indication: Premature Infants (Largest) vs. Infants with Low Birth Weight (Fastest-Growing)

In the Necrotising Enterocolitis Market, indications present diverse shares among various patient demographics. Premature infants represent the largest segment, significantly contributing to the incidence of necrotising enterocolitis due to their underdeveloped gastrointestinal systems. On the other hand, infants with low birth weight are increasingly acknowledged, capturing substantial attention from healthcare providers as they experience a rising prevalence of necrotising enterocolitis. This segment dynamics highlights a concerning trend towards the vulnerability of these groups, ultimately driving research and treatment advancements.

Premature Infants: Dominant vs. Infants with Low Birth Weight: Emerging

Premature infants are at a higher risk for necrotising enterocolitis (NEC), making them the dominant segment in this market. Their underdeveloped digestive systems lead to an increased susceptibility to intestinal injury, prompting urgent clinical interventions. Conversely, infants with low birth weight represent an emerging segment, as their unique clinical profiles and rising numbers are underscored by heightened vulnerability to NEC. This group requires specialized care and dietary management to mitigate risk, resulting in targeted research efforts and innovative treatment solutions tailored to improve outcomes. Both segments highlight significant challenges and opportunities in improving pediatric gastrointestinal health.

By Treatment Type: Surgical Intervention (Largest) vs. Pharmacological Treatment (Fastest-Growing)

In the Necrotising Enterocolitis Market, treatment types are primarily categorized into Surgical Intervention, Pharmacological Treatment, Nutritional Support, and Supportive Care. Surgical Intervention holds the largest market share, driven by the essential need for immediate corrective measures in severe cases. Pharmacological Treatment, while currently smaller, is rapidly gaining traction as advancements in drug therapies enhance their efficacy in early interventions, thus improving patient outcomes. Growth trends for this segment highlight an increasing focus on innovative treatment solutions, propelled by ongoing clinical research and heightened awareness of necrotising enterocolitis. The rise in incidences of this condition also fuels demand for both surgical and pharmacological approaches, with a notable shift towards less invasive pharmacological options that align with patient recovery needs and healthcare provider preferences.

Surgical Intervention (Dominant) vs. Nutritional Support (Emerging)

Surgical Intervention remains the dominant treatment type within the Necrotising Enterocolitis Market, recognized for its critical role in managing life-threatening cases. It encompasses procedures that are imperative for bowel resection and necessary interventions for severe intestinal necrosis. In contrast, Nutritional Support is emerging as a significant complement to surgical and pharmacological treatments. It emphasizes the importance of feeding strategies, including enteral feeds and parenteral nutrition, to support growth and healing in affected infants. As research indicates the long-term benefits of appropriate nutritional management post-treatment, this segment is gaining investment and attention, positioning itself as a vital area within necrotising enterocolitis care.

By End User: Hospitals (Largest) vs. Specialized Neonatal Units (Fastest-Growing)

The End User segment in the Necrotising Enterocolitis Market includes various pivotal entities, such as Hospitals, Specialized Neonatal Units, Research Institutions, and Home Care Settings. Currently, Hospitals dominate this segment, as they provide comprehensive care for the most critical cases of necrotising enterocolitis. Specialized Neonatal Units follow closely, providing necessary expertise and technology for the treatment of premature infants susceptible to NEC. Research Institutions and Home Care Settings, while essential, currently acquire a smaller share of the market, focusing on research advancements and at-home care, respectively.

Hospitals (Dominant) vs. Home Care Settings (Emerging)

Hospitals play a dominant role in the Necrotising Enterocolitis Market due to their capacity to offer extensive medical care, including surgical interventions and advanced diagnostic tools. They cater to a wide range of patients with varying severity of necrotising enterocolitis, leading to their market leadership. In contrast, Home Care Settings are emerging as a vital segment, particularly driven by the shift towards patient-centered care. These settings are becoming increasingly significant as they provide tailored management plans that allow for continued recovery after hospital discharge. As medical technology advances and support for home-based care improves, Home Care Settings are gaining traction, reflecting a changing landscape in the management of necrotising enterocolitis.

By Diagnosis Method: Clinical Assessment (Largest) vs. Imaging Techniques (Fastest-Growing)

In the Necrotising Enterocolitis Market, Clinical Assessment is the largest segment, holding a significant share of the overall market. This method relies on thorough physical examinations and clinical evaluations to diagnose necrotising enterocolitis, making it an essential tool in neonatal care. Meanwhile, Imaging Techniques, including x-rays and ultrasound, are gaining momentum, attributed to advancements in technology that enhance diagnostic accuracy.

Diagnosis Techniques: Clinical Assessment (Dominant) vs. Imaging Techniques (Emerging)

Clinical Assessment is recognized as the dominant diagnosis method in the necrotising enterocolitis market due to its foundational role in diagnosing this critical condition through direct evaluation of symptoms and clinical history. However, Imaging Techniques are emerging vigorously, aided by innovations that allow for non-invasive and rapid diagnosis, integrating modern imaging modalities like ultrasound and MRI into clinical practices. This shift is driven by the high accuracy and reliability these technologies offer, promoting early detection and treatment. The balance between traditional and innovative approaches is shaping the future of diagnosis in this specialized market.

Get more detailed insights about Necrotising Enterocolitis Market

Regional Insights

North America : Market Leader in Innovation

North America holds the largest share of the Necrotising Enterocolitis market, valued at $2.72B in 2025. The region benefits from advanced healthcare infrastructure, high R&D investments, and a growing prevalence of neonatal conditions. Regulatory support from agencies like the FDA accelerates the approval of innovative therapies, driving market growth. The increasing focus on pediatric healthcare and rising awareness about NEC are also significant demand drivers. The competitive landscape in North America is robust, featuring key players such as AbbVie Inc, Baxter International Inc, and Pediatric Bioscience LLC. These companies are actively engaged in developing novel treatments and therapies for NEC. The presence of leading pharmaceutical firms ensures a steady supply of advanced medical solutions, contributing to the region's market dominance. The collaboration between healthcare providers and pharmaceutical companies further enhances the treatment landscape for NEC.

Europe : Emerging Market with Growth Potential

Europe's Necrotising Enterocolitis market is valued at $1.54B in 2025, driven by increasing neonatal care initiatives and rising awareness of NEC. The region benefits from stringent regulatory frameworks that ensure the safety and efficacy of treatments. Countries like Germany and the UK are at the forefront, with significant investments in healthcare infrastructure and research. The growing prevalence of preterm births is also a critical factor fueling market demand. Leading countries in Europe include Germany, the UK, and France, where key players like Fresenius Kabi AG and Takeda Pharmaceutical Company Limited are actively involved. The competitive landscape is characterized by collaborations between pharmaceutical companies and healthcare institutions, enhancing treatment options for NEC. Regulatory bodies are focused on improving pediatric healthcare, which is expected to further boost market growth in the coming years.

Asia-Pacific : Rapidly Growing Healthcare Sector

The Asia-Pacific Necrotising Enterocolitis market is projected to reach $1.1B by 2025, driven by increasing healthcare investments and rising awareness of neonatal health issues. Countries like Japan and Australia are leading the charge, with government initiatives aimed at improving pediatric care. The growing prevalence of preterm births in the region is a significant demand driver, alongside advancements in medical technology and treatment options. The competitive landscape in Asia-Pacific is evolving, with key players such as Takeda Pharmaceutical Company Limited and MediWound Ltd making strides in the market. The presence of local manufacturers and increasing collaborations with international firms are enhancing the availability of NEC treatments. Regulatory support from national health authorities is crucial in fostering innovation and ensuring the safety of new therapies, contributing to the region's growth trajectory.

Middle East and Africa : Emerging Market with Challenges

The Middle East and Africa Necrotising Enterocolitis market is valued at $0.08B in 2025, reflecting the region's emerging healthcare landscape. Challenges such as limited healthcare infrastructure and lower awareness of NEC hinder market growth. However, increasing investments in healthcare and government initiatives aimed at improving neonatal care are expected to drive demand. The rising incidence of preterm births is also a critical factor influencing market dynamics. Countries like South Africa and the UAE are making progress in addressing NEC through improved healthcare policies and collaborations with international organizations. The competitive landscape is characterized by a mix of local and international players, although the market remains underdeveloped compared to other regions. Efforts to enhance healthcare access and treatment options are essential for fostering growth in this market.

Key Players and Competitive Insights

The Necrotising Enterocolitis Market is characterized by a dynamic competitive landscape, driven by increasing awareness of neonatal health and advancements in treatment modalities. Key players such as AbbVie Inc (US), Baxter International Inc (US), and Takeda Pharmaceutical Company Limited (JP) are strategically positioned to leverage innovation and partnerships to enhance their market presence. AbbVie Inc (US) focuses on developing novel therapies, while Baxter International Inc (US) emphasizes supply chain optimization to ensure timely delivery of critical products. Takeda Pharmaceutical Company Limited (JP) is actively pursuing collaborations with research institutions to foster innovation in treatment options, collectively shaping a competitive environment that prioritizes patient outcomes and technological advancements.

The market structure appears moderately fragmented, with several players vying for market share. Key business tactics include localizing manufacturing to reduce costs and enhance supply chain efficiency. This approach not only mitigates risks associated with global supply chain disruptions but also allows companies to respond swiftly to regional demands. The collective influence of these key players is significant, as they drive competition through strategic initiatives that focus on quality, accessibility, and innovation.

In November 2025, AbbVie Inc (US) announced a partnership with a leading research institution to develop a groundbreaking therapy aimed at reducing the incidence of necrotising enterocolitis in preterm infants. This collaboration is expected to accelerate the development of new treatment options, potentially transforming the standard of care in neonatal units. The strategic importance of this partnership lies in its potential to enhance AbbVie’s portfolio and reinforce its commitment to addressing unmet medical needs in this vulnerable population.

In October 2025, Baxter International Inc (US) launched a new line of enteral nutrition products specifically designed for neonates at risk of necrotising enterocolitis. This product line aims to provide tailored nutritional support, which is crucial for the growth and development of premature infants. The introduction of these products underscores Baxter's focus on innovation and its dedication to improving patient outcomes, thereby strengthening its competitive position in the market.

In September 2025, Takeda Pharmaceutical Company Limited (JP) expanded its global reach by entering into a strategic alliance with a European biotech firm to co-develop a novel biologic therapy for necrotising enterocolitis. This alliance is indicative of Takeda's strategy to enhance its research capabilities and diversify its product offerings. The collaboration is expected to yield significant advancements in treatment options, positioning Takeda as a leader in the market.

As of December 2025, current competitive trends indicate a shift towards digitalization, sustainability, and the integration of AI in product development and patient care. Strategic alliances are increasingly shaping the landscape, enabling companies to pool resources and expertise to drive innovation. The competitive differentiation is likely to evolve from traditional price-based competition to a focus on technological advancements, quality of care, and supply chain reliability, reflecting a broader industry trend towards value-based healthcare.

Key Companies in the Necrotising Enterocolitis Market market include

Industry Developments

June 2022 The Exclusive Human Milk Diet, which includes Prolacta Bioscience products (Prolacta's EHMD), has been used in the neonatal intensive care unit (NICU) with the first evidence-based feeding approach just being introduced by Prolacta Bioscience. The EHMD Protocol TM from Prolacta is the first nutritional recommendation for the use of the company's human milk-based nutritional products, and it addresses the nutritional issues of delayed and inadequate sustenance presented by low birth weight preterm newborns.

February 2021 Through the enrollment of 300 preterm children in the ongoing clinical Phase III research of IBP-9414, Infant Bacterial Therapeutics (IBT) achieved a significant milestone. In order to enroll children with extremely low birth weights, this means that a safety investigation of these newborns will be carried out. It is anticipated that this will significantly increase recruitment rates. It is anticipated that the investigation will be finished by November 2022. The expansion of the  market may be significantly impacted by this study's success.

March 2018 Prometic Life Sciences Inc.'s Inter-Alpha-Inhibitor-Proteins, which is anticipated to be a major medication for the treatment of necrotizing enterocolitis, received approval from the U.S. Food and Drug Administration (FDA) department.

Future Outlook

Necrotising Enterocolitis Market Future Outlook

The Necrotising Enterocolitis Market is projected to grow at a 5.5% CAGR from 2024 to 2035, driven by advancements in neonatal care, increased awareness, and innovative treatment options.

New opportunities lie in:

  • Development of targeted probiotics for NEC prevention
  • Investment in telemedicine platforms for remote monitoring
  • Partnerships with hospitals for integrated care solutions

By 2035, the market is expected to demonstrate robust growth and enhanced treatment options.

Market Segmentation

Necrotising Enterocolitis Market End User Outlook

  • Hospitals
  • Specialized Neonatal Units
  • Research Institutions
  • Home Care Settings

Necrotising Enterocolitis Market Indication Outlook

  • Premature Infants
  • Full-Term Infants
  • Neonatal Patients
  • Infants with Low Birth Weight

Necrotising Enterocolitis Market Treatment Type Outlook

  • Surgical Intervention
  • Pharmacological Treatment
  • Nutritional Support
  • Supportive Care

Necrotising Enterocolitis Market Diagnosis Method Outlook

  • Clinical Assessment
  • Imaging Techniques
  • Laboratory Tests
  • Endoscopic Procedures

Report Scope

MARKET SIZE 20245.44(USD Billion)
MARKET SIZE 20255.74(USD Billion)
MARKET SIZE 20359.81(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.5% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledAbbVie Inc (US), AstraZeneca PLC (GB), Baxter International Inc (US), Fresenius Kabi AG (DE), MediWound Ltd (IL), Pediatric Bioscience LLC (US), Sobi AB (SE), Takeda Pharmaceutical Company Limited (JP)
Segments CoveredIndication, Treatment Type, End User, Diagnosis Method
Key Market OpportunitiesAdvancements in neonatal care technologies enhance prevention and treatment options in the Necrotising Enterocolitis Market.
Key Market DynamicsRising prevalence of necrotising enterocolitis drives demand for innovative treatment options and enhanced clinical protocols.
Countries CoveredNorth America, Europe, APAC, South America, MEA

Market Highlights

Author
Rahul Gotadki
Assistant Manager

He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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FAQs

What is the projected growth of the Necrotising Enterocolitis market?

The Necrotising Enterocolitis market is the expected increase in total market value of 9.81 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

What is the size of the Necrotising Enterocolitis market?

Necrotising Enterocolitis market size was valued at approximately 5.44 billion USD in 2024. This figure will reach 9.81 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

What is the CAGR of the Necrotising Enterocolitis market?

Necrotising Enterocolitis market is expected to grow at a CAGR of 5.5% between 2025 and 2035.

How much will the Necrotising Enterocolitis market be worth by 2035?

Necrotising Enterocolitis market is expected to be worth of 9.81 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

How will the Necrotising Enterocolitis market perform over the next 10 years?

Over the next 10 years the Necrotising Enterocolitis market is expected to shift from usd billion 5.44 to 9.81 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

Which region held the largest market share in the necrotising enterocolitis market?

North America had the largest share in the market.

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