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Japan Microbiome Sequencing Services Market Research Report: By Technology (Sequencing by Litigation (SBL), Sequencing by Synthesis (SBS), Short Gun Sequencing, Targeted Gene Sequencing, RNA Sequencing, Others) andBy Application (Gastrointestinal Diseases, Infectious Diseases, CNS Diseases, Oncology, Others)- Forecast to 2035


ID: MRFR/HC/52147-HCR | 200 Pages | Author: Garvit Vyas| May 2025

Japan Microbiome Sequencing Services Market Overview:


As per MRFR analysis, the Japan Microbiome Sequencing Services Market Size was estimated at 70.97 (USD Million) in 2023. The Japan Microbiome Sequencing Services Market Industry is expected to grow from 78(USD Million) in 2024 to 386 (USD Million) by 2035. The Japan Microbiome Sequencing Services Market CAGR (growth rate) is expected to be around 15.647% during the forecast period (2025 - 2035).


Key Japan Microbiome Sequencing Services Market Trends Highlighted


Several substantial trends are currently being observed in the Japan Microbiome Sequencing Services Market, which is being driven by technological advancements and an increasing emphasis on personalized medicine. The Japanese government has been actively promoting research initiatives to improve comprehension of the human microbiome, thereby nurturing collaborations between academia and industry. 


This has led to an increased demand for microbiome sequencing services, which are intended to address a variety of health concerns, such as disease prevention and gastrointestinal health. Moreover, the expansion of this market is being facilitated by the emergence of biotechnology companies in Japan, which are utilizing innovative sequencing techniques to conduct more comprehensive and precise microbiome-based analyses. Integration of sequencing data with artificial intelligence and big data analytics to enhance health outcomes is one of the opportunities in the Japan Microbiome Sequencing Services Market.


The potential to captivate new segments of consumers who are seeking customized healthcare solutions based on their microbiome profiles is present as more organizations in Japan invest in data-driven healthcare solutions. Furthermore, healthcare providers are being compelled to incorporate microbiome analysis into their standard practices as a result of the growing recognition of the microbiome's relevance to a variety of diseases, including obesity, diabetes, and mental health disorders. In recent years, there has been an increase in the popularity of lifestyle modifications and preventive healthcare, which are encouraged by microbiome insights.Additionally, the demand for microbiome analysis in dietary recommendations is being further bolstered by the growing interest in nutraceuticals that promote digestive health. 


The country is positioned as a significant player in the global microbiome sequencing landscape as a result of the focus on research and development in microbiome-related disciplines, which is driven by Japan's robust healthcare system. The Japan Microbiome Sequencing Services Market is on the brink of further expansion, which will be fueled by enhanced consumer awareness and technological innovation, as these trends continue to develop.


Japan Microbiome Sequencing Services Market size


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Japan Microbiome Sequencing Services Market Drivers


Growing Awareness of the Human Microbiome's Role in Health


In Japan, there is a rapidly increasing awareness among both healthcare professionals and the general public regarding the significance of the human microbiome in health conditions including gastrointestinal diseases, obesity, and immune disorders. According to the Ministry of Health, Labour and Welfare in Japan, approximately 30% of the Japanese population suffers from gastrointestinal issues, which is leading to an intensified focus on the microbiome as a therapeutic target.Furthermore, institutions like the RIKEN Center for Integrative Medical Sciences are driving Research and Development (R&D) initiatives aimed at understanding the microbiome's role in health, thereby propelling the Japan Microbiome Sequencing Services Market Industry. As awareness grows, demand for microbiome sequencing services is expected to surge, contributing significantly to market growth.


Advancements in Sequencing Technologies


The advancement in sequencing technologies has made microbiome analysis more accessible and cost-effective in Japan. Innovations such as Next-Generation Sequencing (NGS) are providing accurate and rapid results, attracting both academic and commercial entities. For instance, with the support from the Japan Science and Technology Agency, various public universities are developing state-of-the-art sequencing platforms. This improvement has resulted in a price reduction of microbiome sequencing services by up to 40% over the past five years.Such technological strides are expected to enhance the adoption of microbiome sequencing services in the Japan Microbiome Sequencing Services Market Industry, thereby driving its growth.


Rising Demand for Personalized Medicine


The personalized medicine trend is flourishing in Japan, with a growing emphasis on tailored healthcare solutions based on individual genetic and microbiomic profiles. The Japanese government has set forth initiatives promoting personalized medicine as a means to optimize patient care and reduce healthcare costs. According to recent reports, around 60% of Japanese doctors are now considering microbiome data in their treatment decisions. The partnership between Renowned University of Tokyo and various biotech companies is enhancing the research on using microbiome data for patient stratification in treatments, thus spurring growth in the Japan Microbiome Sequencing Services Market Industry.


Japan Microbiome Sequencing Services Market Segment Insights:


Microbiome Sequencing Services Market Technology Insights


The Japan Microbiome Sequencing Services Market within the Technology segment plays a crucial role in advancing genomic research and healthcare solutions. This segment includes various methods such as Sequencing by Litigation (SBL), Sequencing by Synthesis (SBS), Short Gun Sequencing, Targeted Gene Sequencing, RNA Sequencing, and others, each contributing uniquely to the understanding of microbiomes. 


For instance, Short Gun Sequencing is recognized for its comprehensive approach, allowing the analysis of entire genomes, which is vital for accurate microbiome characterization.In contrast, Sequencing by Synthesis (SBS) holds a significant position due to its ability to provide high-throughput sequencing data, making it indispensable for large-scale genomic studies. 


Targeted Gene Sequencing focuses on specific areas of interest, thereby expediting discovery in clinical applications by honing in on genes that influence health outcomes. Additionally, RNA Sequencing has gained traction as it offers valuable insights into gene expression patterns, essential for understanding microbial interactions and functions in various environments.This diversity in technological approaches fosters innovation and enhances the overall capabilities of microbiome research in Japan. The continuous evolution of these techniques is driven by advancements in computational tools and bioinformatics, enabling researchers to process and analyze vast amounts of data efficiently.


The Japanese government actively supports microbiome research through funding initiatives and collaboration with academic institutions, positioning the country to lead in this burgeoning field. Overall, the significance and interplay of these technological methods highlight the critical opportunities and challenges faced within the Japan Microbiome Sequencing Services Market.


Japan Microbiome Sequencing Services Market Segment


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Microbiome Sequencing Services Market Application Insights


The Application segment of the Japan Microbiome Sequencing Services Market plays a crucial role in addressing a variety of health issues and enhancing patient outcomes. With the increasing prevalence of gastrointestinal diseases, there is growing interest in understanding how microbiome composition influences these conditions. Infectious diseases also benefit significantly from microbiome research, as insights gained can lead to better diagnostic and therapeutic approaches.


CNS diseases represent another vital area as emerging studies link gut microbiota to neurological health, suggesting new avenues for treatment.Oncology, too, is gaining traction, with research exploring the interplay between the microbiome and cancer therapies, potentially paving the way for personalized medicine. The category of 'Others' encompasses various applications that further underline the market's versatility and the increasing recognition of the microbiome's role in overall health. The rising investment in Research and Development for these applications contributes to the ever-expanding landscape of the Japan Microbiome Sequencing Services Market, indicating significant opportunities for growth and innovation within the industry.


Japan Microbiome Sequencing Services Market Key Players and Competitive Insights:


The Japan Microbiome Sequencing Services Market is characterized by a rapidly evolving landscape as advancements in sequencing technology and a growing understanding of the microbiome's role in health and disease spur increased investment and interest in this field. Within this market, a variety of players range from established biotechnology firms to emerging startups, each seeking to capitalize on the immense potential of microbiome research. 


Competitive dynamics are influenced by factors such as technological innovation, research partnerships, and the integration of bioinformatics services. As companies navigate this landscape, they are focused on differentiating their offerings through specialization in service delivery, precision, and comprehensive data analysis, making it essential for stakeholders to remain attuned to shifts in consumer demand and regulatory frameworks.GeneWiz stands out within the Japan Microbiome Sequencing Services Market due to its robust reputation for high-quality sequencing and customer service. 


The company offers an extensive range of genomics services, including microbiome analysis, which is vital for understanding the complex interactions within microbial communities. GeneWiz has established significant market presence in Japan, leveraging its advanced technological capabilities and a team of skilled professionals to deliver precise insights. 


This strength is complemented by their commitment to innovation and customer support, which has earned them a loyal clientele. Furthermore, GeneWiz maintains strategic collaborations with academic institutions and research organizations in Japan, further enhancing its position and allowing for the continuous evolution of its service offerings in response to market needs.Zymo Research is another key player in the Japan Microbiome Sequencing Services Market, having made considerable strides in providing cutting-edge products and services that facilitate microbiome research. 


The company specializes in innovative solutions such as DNA and RNA extraction kits, library preparation kits, and microbial profiling solutions, which cater directly to the requirements of researchers in Japan. Zymo Research's strengths lie in its advanced product suite and a strong focus on enhancing the reproducibility and accuracy of microbial studies, which has resulted in widespread adoption in both academic and clinical settings. 


The company's market presence is further reinforced by a series of strategic partnerships and collaborations within Japan’s research community, coupled with efforts to expand its offerings through mergers and acquisitions that align with its mission. Through its commitment to research-driven innovation, Zymo Research is well-positioned as a formidable entity in the growing field of microbiome sequencing.


Key Companies in the Japan Microbiome Sequencing Services Market Include:



  • GeneWiz

  • Zymo Research

  • Fulgent Genetics

  • Macrogen

  • BioRad Laboratories

  • Roche

  • Qiagen

  • Eurofins Scientific

  • Dunlee

  • Thermo Fisher Scientific

  • Illumina

  • Novogene

  • Agilent Technologies

  • Microbial Genomics

  • BGI Genomics


Japan Microbiome Sequencing Services Market Industry Developments


Recent developments in the Japan Microbiome Sequencing Services Market include increased investment and growth from various companies as consumer interest in personalized medicine rises. Notably, GeneWiz and Zymo Research have been at the forefront of offering innovative sequencing solutions tailored to the Japanese market demand. In a significant event, Macrogen announced a strategic partnership with Qiagen in July 2023 aimed at expanding their microbiome analysis capabilities in Japan.


Additionally, Thermo Fisher Scientific revealed plans in August 2023 to enhance its operational footprint in Japan, reflecting the company's commitment to meet the growing demand for advanced sequencing technologies. The market has seen strong valuation growth due to these advancements, with organizations actively exploring collaborations to leverage genomic data. Over the past two to three years, the demand for microbiome research related to gut health has significantly gained traction in Japan, leading to an increased focus on R&D initiatives. Companies such as Illumina and Eurofins Scientific continue to play essential roles in advancing microbiome sequencing services, indicating a thriving landscape for genetic research and diagnostics in Japan.


Japan Microbiome Sequencing Services Market Segmentation Insights


Microbiome Sequencing Services Market Technology Outlook



  • Sequencing by Litigation (SBL)

  • Sequencing by Synthesis (SBS)

  • Short Gun Sequencing

  • Targeted Gene Sequencing

  • RNA Sequencing

  • Others


Microbiome Sequencing Services Market Application Outlook



  • Gastrointestinal Diseases

  • Infectious Diseases

  • CNS Diseases

  • Oncology

  • Others


 

Report Scope:,,,,,,,,,,,,,
Report Attribute/Metric Source: Details
MARKET SIZE 2018 70.97(USD Million)
MARKET SIZE 2024 78.0(USD Million)
MARKET SIZE 2035 386.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 15.647% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Million
KEY COMPANIES PROFILED GeneWiz, Zymo Research, Fulgent Genetics, Macrogen, BioRad Laboratories, Roche, Qiagen, Eurofins Scientific, Dunlee, Thermo Fisher Scientific, Illumina, Novogene, Agilent Technologies, Microbial Genomics, BGI Genomics
SEGMENTS COVERED Technology, Application
KEY MARKET OPPORTUNITIES Growing awareness of gut health, Rising demand for personalized medicine, Expansion in research funding, Technological advancements in sequencing, Increasing applications in agriculture
KEY MARKET DYNAMICS rising healthcare expenditure, increasing research activities, growing demand for personalized medicine, advancements in sequencing technologies, supportive government initiatives
COUNTRIES COVERED Japan


Frequently Asked Questions (FAQ) :

The Japan Microbiome Sequencing Services Market is expected to be valued at 78.0 million USD in 2024.

By 2035, the Japan Microbiome Sequencing Services Market is anticipated to reach a value of 386.0 million USD.

The expected CAGR for the Japan Microbiome Sequencing Services Market from 2025 to 2035 is 15.647%.

By 2035, Sequencing by Synthesis (SBS) is projected to dominate the market with an estimated value of 98.0 million USD.

In 2024, Sequencing by Litigation (SBL) is expected to be valued at 15.0 million USD.

Key players in the market include GeneWiz, Zymo Research, Fulgent Genetics, Macrogen, BioRad Laboratories, and Roche.

The market size for Targeted Gene Sequencing is expected to be 89.0 million USD by 2035.

Emerging trends in personalized medicine and advances in genomic technologies present significant growth opportunities.

Global conflicts could impact supply chains and market dynamics, potentially affecting growth in the sector.

By 2035, RNA Sequencing is expected to reach a market value of 77.0 million USD.

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