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Bioactive Fillings Market Research Report By Material (Silicon Dioxide Based, Calcium Oxide Based, Phosphorus Pentoxide Based, and Sodium Oxide Based), By Application (Orthopedic, Dental, Tissue Engineering), and By End-User - Global Forecast till 2030


ID: MRFR/MED/0432-HCR | 110 Pages | Author: Rahul Gotadki| April 2024

Bioactive Fillings Market Overview



The bioactive fillings market is expected to reach USD 5663.65 Million by 2030 and the market is projected to grow at a CAGR of ~ 8.50 % during the forecast period 2022-2030.Bioactive fillings are surface reactive glass-ceramic biomaterials and have interaction with biological tissues. Bioactive fillings have biocompatibility and bioactivity and thus have a high application as implant material in the human body to repair and replace diseased tissue. Bioactive fillings reacts with the biological tissues in two phases. In the first phase, alkali metal ions are leached from the glass and replaced with hydrogen ions and in the second phase, the Si-O-Si bonds in the silica matrix undergo hydrolysis, yielding a gel-like surface layer rich on Si-O-H groups. In the ultimate stage, calcium phosphate-rich layer forms over the surface of the filling, sealing any further leaching. Bioactive fillings, interact with the body, and have been used in orthopaedics for decades. Bioactive fillings are made from compounds such as silicon oxide, calcium oxide, and phosphorous oxide, and has antimicrobial effect due to the release of calcium and phosphate ions which have an antibacterial activity and also tend to neutralize the local acidic pH. Bioactive fillings prolong the life of fillings because their antibacterial effects and replacement of lost minerals.

The market drivers for bioactive fillings market are rise in demand due to growing population, technological advancements, greater emphasis on restorative procedures, rising safety and success of bioactive fillings treatment, and others. The market restraints are poor mechanical weakness, low fracture resistance, poor load-bearing capacity and mechanical strength, possible toxicity, high cost of bioactive fillings treatment, rejection of the bioactive fillings and others.


Intended Audience



  • Bioactive fillings manufacturers & suppliers

  • Research and development (R&D) companies

  • Hospitals and clinics

  • Academic institutes and universities


Figure 1     Bioactive Fillings Market by Applications (%) Bioactive Fillings Market

Bioactive Fillings Market Segment Insights


Bioactive Fillings Material Insights


Based on the material, the market has been segmented as silicon dioxide based, calcium oxide based, phosphorus pentoxide based, and sodium oxide based.


Bioactive Fillings Applications Insights


Based on the applications, the Bioactive Fillings Market has been segmented as orthopedic, dental, tissue engineering and others.


Bioactive Fillings End User Insights


Based on the end user, the market has been segmented as orthopedic hospitals, dental hospitals, research and academics and others.


Bioactive Fillings Regional Insights


The Americas account for a significant market share owing to high expenditure on the health care especially of the U.S. and Canada. Additionally, the greater number of restorative procedures in the U.S. and Canada drives the bioactive fillings market. The high concentration of the major hospitals in the developed countries of this region coupled with good reimbursement rates is adding fuel to the market growth. Moreover, the large share of surgical restoration segment procedures in the returns of hospitals favors the market. The large number of medical devices companies in the U.S. is also a cause for the faster development of bioactive fillings market in the US.


Europe is the second largest market in the world due to growing medical devices industry and healthcare penetration. The European market growth is led by countries such as Germany and France. Germany is expected to be the fastest growing market over the assessment period due to its large medical devices industry and its large research base.


Asia Pacific region is expected to grow rapidly. China and India are likely to lead this market due to fast growing healthcare sector and large unmet needs over the forecast period. The South East Asian countries such as China, India, and Malaysia are projected to contribute highly to the market growth. The growing penetration of healthcare industry in the Asia Pacific region is expected to drive the future bioactive fillings market in the region.


Gulf nations such as Saudi Arabia and the UAE are estimated to drive the Middle East & African market. Other Middle East nations to watch out for are Kuwait, Jordan, Egypt and Iran. The African region is expected to witness a poor growth owing to poor economic and political conditions, and poor healthcare development. Other regions are expected to be laggards due to poor social development and tribal identities such as sub Saharan Africa.


Key Players in the Bioactive fillings Market


Some of the key players profiled in the report are Septodont, Inc., DePuy Synthes, Medtronic, Stryker, Zimmer Biomet, SCHOTT AG, Aap Implantate AG, GNI GROUP LTD., Arthrex, Inc., Baxter, and others.

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