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    Antifungal Treatment Market

    ID: MRFR/Pharma/1097-CR
    128 Pages
    Rahul Gotadki
    February 2024

    Antifungal Treatment Market Research Report by Drug Class (Azoles, Echinocandins, Polyenes, Allylamine, Pyrimidines, and Others), by Technology (Oral, Topical, and Parenteral), by Indication (Dermatophytosis, Aspergillosis, Candidiasis, Invasive Candidiasis, Vulvovaginal Candidiasis, Mouth/Throat/Esophageal Candidiasis, and Others), by Pathogen (Candida, Aspergillus, Cryptococcus, Coccidioides Immitis, Zygomycetes, Trichophyton, and Others), by Pathogen (Hospitals & Clinics, Dermatology Clinics, and Others), and by Region (North America,...

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    Antifungal Treatment Market Summary

    As per Market Research Future Analysis, the Antifungal Treatment Market was valued at USD 16.85 billion in 2023 and is projected to grow to USD 17.5054 billion by 2032, with a CAGR of 3.89% from 2024 to 2032. The market growth is driven by the increasing incidence of fungal infections and the rising prevalence of immunological diseases. Notable developments include Basilea Pharmaceutica's acquisition of GR-2397, now BAL2062, which shows promise in treating invasive mold infections. Bayer's Canesten product line has also been enhanced to address skin infections effectively.

    Key Market Trends & Highlights

    Key trends influencing the Antifungal Treatment Market include the rising incidence of fungal infections and innovative product launches.

    • Over 75,000 hospitalizations and nearly 9 million outpatient visits occur annually for fungal diseases in the US.
    • Candidiasis held the largest market share in 2022, driven by increasing prevalence and awareness.
    • Topical administration dominated the market in 2022, while parenteral is expected to register the highest CAGR from 2024 to 2032.
    • The azoles segment held the largest market share in 2022, with a broad spectrum of activity against fungal infections.

    Market Size & Forecast

    2023 Market Size USD 16.85 Billion
    2032 Market Size USD 17.5054 Billion
    CAGR (2024-2032) 3.89%

    Major Players

    Pfizer Inc (US), Johnson & Johnson Services, Inc (US), Bayer AG (Germany), Novartis AG (Switzerland), Abbott Laboratories, Inc. (US), Merck KGaA (Germany), Gilead Sciences, Inc (US), Cipla, Inc. (India), Sanofi S.A. (France), GlaxoSmithKline Plc (UK)

    Antifungal Treatment Market Trends

    Increasing incidence of fungal infections

     Fungal infections encompass both systemic and superficial infections, including infections of the skin, eye, mouth, and vagina. Antifungal products with fungicidal activity are mostly used to treat a wide array of diseases, such as athlete's foot, ringworm, and fungal meningitis, caused by fungal agents. According to the Centers for Disease Control and Prevention (US), more than 75,000 hospitalizations and nearly 9 million outpatient visits occur every year for fungal diseases in the US.

    Moreover, there are several products available associated with different routes of administration on the market for the treatment of fungal infections, such as oral and intravenous medicines, creams, sprays, shampoos, solutions, pessaries, and injections. In addition, increasing launches of innovative products is further fueling the growth of the market. For instance, in May 2022, Bayer AG (Germany) launched a new and improved Canesten antifungal treatment solution in India. The product line, which is available in powder and cream forms, has anti-fungal properties that aid in the prevention and treatment of skin infections.

    The antifungal cream provides relief from infection, and the mild steroid cream reduces the inflammation due to infection.

    Hence, the high availability of different routes of administration and the rising prevalence of different types of fungal infections are fostering market growth.

    The increasing prevalence of fungal infections, coupled with the rising awareness of antifungal treatments, suggests a robust growth trajectory for the global antifungal treatment market.

    World Health Organization (WHO)

    Antifungal Treatment Market Drivers

    Market Trends and Projections

    The Global Antifungal Treatment Market Industry is characterized by various trends and projections that indicate its future trajectory. The market is expected to reach 16.9 USD Billion in 2024, with a gradual increase to 19.6 USD Billion by 2035. This growth reflects a compound annual growth rate (CAGR) of 1.4% from 2025 to 2035. Factors such as rising incidences of fungal infections, advancements in drug development, and increased awareness are likely to shape the market landscape. These trends suggest a robust future for the antifungal treatment sector, driven by ongoing innovations and evolving healthcare needs.

    Growing Awareness and Education

    Increased awareness and education regarding fungal infections are pivotal drivers of the Global Antifungal Treatment Market Industry. Public health campaigns and educational initiatives by healthcare organizations aim to inform both healthcare professionals and the general public about the risks associated with fungal infections. This heightened awareness leads to earlier diagnosis and treatment, ultimately increasing the demand for antifungal therapies. As healthcare systems prioritize infection control, the market is likely to benefit from a more informed patient population. Consequently, this trend may contribute to a steady growth rate, with a projected CAGR of 1.4% from 2025 to 2035.

    Emerging Markets and Economic Growth

    Emerging markets are playing a crucial role in the expansion of the Global Antifungal Treatment Market Industry. Countries with developing economies are witnessing an increase in healthcare expenditure, leading to improved access to antifungal treatments. As these nations invest in healthcare infrastructure, the demand for effective antifungal therapies is likely to rise. Additionally, economic growth in these regions may result in a greater focus on public health initiatives, further driving market demand. The combination of rising incomes and increased healthcare access suggests a favorable environment for market growth in the coming years.

    Rise in Immunocompromised Populations

    The Global Antifungal Treatment Market Industry is significantly impacted by the rise in immunocompromised populations, including individuals with HIV/AIDS, cancer patients, and organ transplant recipients. These groups are at a higher risk for severe fungal infections, necessitating effective antifungal treatments. As healthcare providers focus on managing these vulnerable populations, the demand for antifungal medications is expected to increase. This trend is particularly evident in regions with high rates of immunocompromised individuals, where healthcare systems are adapting to address these challenges. The market's growth trajectory appears promising as it aligns with the needs of these populations.

    Rising Incidence of Fungal Infections

    The Global Antifungal Treatment Market Industry is experiencing growth due to the increasing prevalence of fungal infections worldwide. Factors such as climate change, urbanization, and immunocompromised populations contribute to this rise. For instance, the World Health Organization indicates that fungal infections affect millions globally, particularly in developing regions. This surge in infections necessitates effective antifungal treatments, thereby driving market demand. As the industry adapts to these challenges, the market is projected to reach 16.9 USD Billion in 2024, reflecting a growing need for innovative therapies and preventive measures.

    Advancements in Antifungal Drug Development

    Innovations in antifungal drug development are significantly influencing the Global Antifungal Treatment Market Industry. The emergence of novel antifungal agents, including echinocandins and triazoles, has expanded treatment options for various fungal infections. These advancements not only enhance efficacy but also aim to reduce side effects, improving patient compliance. Regulatory bodies are increasingly approving new formulations, which may contribute to market growth. As the industry evolves, it is anticipated that the market will continue to expand, with projections indicating a value of 19.6 USD Billion by 2035, driven by ongoing research and development efforts.

    Market Segment Insights

    Antifungal Treatment Market Drug Class Insights

    Based on drug class, the Antifungal Treatment Market is segmented into azoles, echinocandins, polyenes, allylamine, pyrimidines, and others. The azoles segment held the largest market share in 2022, and the polyenes is anticipated to register the highest CAGR from 2024 to 2032. Azoles play a crucial role in the growth of the antifungal disease treatment market due to their effectiveness in combating fungal infections. Azoles are a class of antifungal drugs that inhibit the growth of fungi by interfering with the synthesis of ergosterol, a vital component of fungal cell membranes. 

    The key factors that drive the growth of this segment are broad spectrum of activity of azoles, different administration routes, and increasing prevalence of fungal infections. According to preliminary Centers for Disease Control and Prevention (CDC) data in 2022 reported there were about 2,377 cases of Candida Auris across the U.S. Thus, increase in fungal infections has led to an increase in the demand of azoles drugs across the world for effective antifungal treatment which drives the growth of market.

    Antifungal Treatment Market Route of Administration Insights

    Based on the route of administration, the Antifungal Treatment Market has been segmented into oral, topical, and parenteral. Topical held the largest market share in 2022 and parenteral is anticipated to register the highest CAGR from 2024 to 2032. The segment market growth is attributed to increasing prevalence of fungal infections, rising consumer awareness towards fungal infections and limited systemic side effects drive the key growth of the antifungal treatment market. 

    Furthermore, the launch of innovative products in the market to meet patients and healthcare professionals’ demand is burgeoning the route of administration segment. For instance, in March 2022, Mundipharma (UK) and Cidara Therapeutics, Inc. (US) received an approval from Medicines and Healthcare Products Regulatory Agency (MHRA) for Rezafungin for the treatment of invasive candidiasis

    Antifungal Treatment Market Indication Insights

    The Antifungal Treatment Market, based on the indication, has been segmented into dermatophytosis, aspergillosis, candidiasis, invasive candidiasis, vulvovaginal candidiasis, mouth/throat/esophageal candidiasis, and others. Candidiasis held the largest market share in 2022, and dermatophytosis is anticipated to register the highest CAGR from 2024 to 2032. 

    The segment market growth is driven by the increasing prevalence of candidiasis, and growing awareness and diagnosis drive the key growth of the antifungal treatment market. Moreover, there is an increase in the launch of new options to treat patients with candidiasis, a deadly fungal infection. For instance, in March 2023, Cidara Therapeutics, Inc. (US) and Melinta Therapeutics, LLC (US) received US Food and Drug Administration approval for REZZAYO for the treatment of invasive candidiasis in adults with limited or no alternative treatment options, furthering creative flourishing opportunities for the market.

    FIGURE 2: ANTIFUNGAL TREATMENT MARKET, BY INDICATION, 2023 & 2032 (USD BILLION)

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Antifungal Treatment Market Pathogen Insights

    Based on pathogens, the Antifungal Treatment Market is segmented into candida, aspergillus, cryptococcus, coccidioides immitis, zygomycetes, trichophyton, and others. Candida held the largest market share in 2022, and cryptococcus is anticipated to register the highest CAGR from 2024 to 2032. 

    The segment’s growth is attributed to the increasing prevalence of vulvovaginal candida and increasing women's healthcare awareness towards candida infections, which drive the key growth of the antifungal treatment market. 

    For instance, according to the National Institute of Health, in 2022, it was estimated that about 138 million women globally experienced recurrent vulvovaginal candida annually.

    Antifungal Treatment Market End User Insights

    The Antifungal Treatment Market, based on the end user, has been segmented into hospitals & clinics, dermatology clinics, and others. Dermatology clinics held the largest market in 2022 with a market share of 47.73% due to rise in the number of patient visits suffering from skin fungal infection across the world boosting the growth of market. 

    Moreover, hospital and clinics segment exhibited the highest growth in the forecast period owing to increase in the demand for antifungal drugs among hospital and clinics for the treatment of various fungal disease drives the growth of market.

    Get more detailed insights about Antifungal Treatment Market Research Report- Forecast till 2032

    Regional Insights

    By region, the study segments the market into North America, Europe, Asia-Pacific, and Rest of the World. North America accounted for the largest market share of over 40% in 2022 is owing to various factors and one of them is increasing number of people with fungal infections. Moreover, market players are forming strategies to distribute and sell antifungal medicine in the US. For instance, in March 2023, GlaxoSmithKline PLC (UK) entered into an agreement with Scynexis, Inc. (US) to commercialize and develop Brexafemme (ibrexafungerp), a first-in-class medicine to treat antifungal in the US.

    Further, the major countries studied are: The US, Canada, Germany, France, the UK, Italy, Spain, China, India, Japan, South Korea, Australia, Brazil.

    FIGURE 3: ANTIFUNGAL TREATMENT MARKET, BY REGION, 2023 & 2032 (USD MILLION) ANTIFUNGAL TREATMENT MARKET, BY REGION, 2022 & 2032

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    The Europe anti-fungal infection market growth is driven by majorly invasive fungal infections, which have been dramatically increasing since the last decade in the European countries. Moreover, patients with hematologic malignancies and hematopoietic cell transplant recipients (HCT) are found to get invasive fungal infections in the European population. 

    Furthermore, as per the Eurosurveillance, an increasing number of cases of Candida auris have been reported in 2021 and 2022 in countries such as France, Germany, Greece, Italy, the Netherlands, Spain, Belgium, and Austria. Furthermore, the Germany antifungal treatment market held the largest market share in 2022 and UK antifungal treatment market is the fastest growing market in the Europe region.

    The Asia-Pacific anti-fungal treatment market is the fastest-growing region during the forecast period owing to increasing fungal infection cases in Asian countries. In 2020, the Global Action for Fungal Infections (GAFFI) and Fudan University (Shanghai) estimated that one million people suffer from invasive aspergillosis in China each year. The populations at risk of invasive aspergillosis are those with lung cancer, chronic obstructive pulmonary diseases , pulmonary tuberculosis, acute myelogenous leukemia, and the late stage of the human immunodeficiency virus. 

    Additionally, fungal infections are more common in tuberculosis patients, thus increasing the incidence of tuberculosis diseases (TB), which is driving the region’s growth. As per the World Health Organization (WHO) Global TB Report 2022, in India, 210 per 1,000,000 people were diagnosed with TB in 2021. Moreover, China antifungal treatment market held the largest market share in 2022 and India antifungal treatment market is the fastest growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    The anti-fungal treatment market is distinguished by the presence of numerous, local players catering to medical devices that are evolving at a rapid pace. The increasing incidents of fungal infections, increasing prevalence of immunological diseases in the anti-fungal treatment, and the availability of wide range of products are further expected to drive the growth of the anti-fungal treatment market during the forecast period. However, the side-effects of treatment may hamper the growth of the anti-fungal treatment market.

    The major players have adopted a strategy of obtaining regulatory approval from government agencies for their drugs and signing contracts and agreements to broaden their reach and reduce operational costs. Moreover, the anti-fungal treatment market is extremely competitive, with players competing, partnering, and investing heavily in R&D to gain a significant market share. The market is moderately fragmented with rising competition, product launches, increasing collaborative partnerships, and other strategic decisions to achieve operational efficiency.

    Pfizer, Inc. (US) manufactures and develops vaccines and medicines for a wide range of medical disciplines that include oncology, cardiology, immunology, diabetology/endocrinology, and neurology. Pfizer also collaborates with healthcare providers, governments, and local communities to support and broaden access to high-quality, reasonably priced healthcare globally. Pfizer distributes its goods through distributors, retailers, hospitals, clinics, public institutions, and pharmacies. The company has R&D platforms in the field of biosimilars, gene therapy, precision medicines, and medicinal sciences. 

    Furthermore, the company supplies its products in North America, South America, Asia-Pacific, Australia, Europe, Africa, and the Middle East. Moreover, in April 2021, the company acquired the biotech firm Amplyx Pharmaceuticals (US) to add more anti-infective drugs to its pipeline and develop antifungal medications. The company's main component, fosmanogepix, is an inventive investigational antifungal that is being created to treat invasive fungal infections.

    Key Companies in the Antifungal Treatment Market market include

    Industry Developments

    March 2023:

    GlaxoSmithKline plc (UK) announced agreement with SCYNEXIS, Inc (US) to commercialize and further develop Brexafemme (ibrexafungerp) for the treatment of fungal infection.

    March 2023:

    Sanofi S.A. (France) announced that it received European commission approval for its product “Dupixent” for the children in case of severe atopic dermatitis.

    May 2022:

    Bayer AG (Germany) has relaunched the antifungal brand Canesten in India to assist consumers treat and prevent skin and foot infections globally. The product line's anti-fungal properties help treat and prevent skin problems. According to a statement from Bayer, Canesten is an easy-to-use formulation for treating full-cycle skin infections that not only reduces itching but also halts the spread of infection.

    December 2020:

    Sanofi S.A. (France) renewed a new five-year USD 25 million partnership with the World Health Organization (WHO) to fight Neglected Tropical Diseases. Neglected tropical diseases (NTDs) refer to a group of parasitic, bacterial, fungal, and viral diseases that affect or threaten over one billion people worldwide.

    Future Outlook

    Antifungal Treatment Market Future Outlook

    The Global Antifungal Treatment Market is projected to grow at a 1.4% CAGR from 2024 to 2035, driven by rising fungal infections and advancements in treatment options.

    New opportunities lie in:

    • Develop novel antifungal agents targeting resistant strains.
    • Expand telehealth services for remote patient monitoring and consultation.
    • Invest in combination therapies to enhance treatment efficacy and reduce resistance.

    By 2035, the market is expected to maintain steady growth, reflecting evolving treatment paradigms and increased demand.

    Market Segmentation

    Antifungal Treatment Market End User Outlook

    • Hospitals & Clinics
    • Dermatology Clinics
    • Others

    Antifungal Treatment Market Pathogen Outlook

    • Candida
    • Aspergillus
    • Cryptococcus
    • Coccidioides Immitis
    • Zygomycetes
    • Trichophyton
    • Others

    Antifungal Treatment Market Regional Outlook

    • US
    • Canada
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • China
    • India
    • Japan
    • South Korea
    • Australia
    • Rest of Asia-Pacific
    • Middle East
    • Africa
    • Latin America

    Antifungal Treatment Market Drug Class Outlook

    • Azoles
    • Echinocandins
    • Polyenes
    • Allylamine
    • Pyrimidines
    • Others

    Antifungal Treatment Market Indication Outlook

    • Dermatophytosis
    • Aspergillosis
    • Candidiasis
    • Invasive Candidiasis
    • Vulvovaginal Candidiasis
    • Mouth/Throat/Esophageal Candidiasis
    • Others

    Antifungal Treatment Market Route of Administration Outlook

    • Oral
    • Topical
    • Parenteral

    Report Scope

    Attribute/Metric Details
    Market Size 2023 USD 16.85 billion
    Market Size 2024 USD 17.5054 billion
    Market Size 2032 USD 23.76 billion
    Compound Annual Growth Rate (CAGR) 3.89% (2024-2032)
    Base Year 2023
    Forecast Period 2024-2032
    Historical Data 2019 & 2022
    Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Segments Covered Drug Class, Route of Administration, Indication, Pathogen, End User, and Region
    Geographies Covered North America, Europe, Asia Pacific, and Rest of the World
    Countries Covered The US, Canada, Brazil, Germany, France, the UK, Italy, Spain, China, India, Japan, South Korea, Australia.
    Key Companies Profiled Pfizer Inc (US), Johnson & Johnson Services, Inc (US), Bayer AG (Germany), Novartis AG (Switzerland), Abbott Laboraotories, Inc. (US), Merck KGaA (Germany), Gilead Sciences, Inc (US), Cipla, Inc. (India), Sanofi S.A. (France), and GlaxoSmithKline Plc (UK)
    Key Market Opportunities ·       Development of new drugs
    Key Market Drivers ·       Increasing incidence of fungal infections·       Increasing prevalence of immunological diseases·       Availability of wide range of products

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    How much is the Antifungal Treatment Market?

    The Antifungal Treatment Market is anticipated to reach 23.76 billion by 2032 at a CAGR of 3.89% during the forecast period of 2024-2032.

    How big is the US antifungal treatment market?

    The US held a 83.28% share of the North America for antifungal treatment market in 2022.

    What is the growth rate of the Antifungal Treatment Market?

    The Antifungal Treatment Market is expected to grow at a 3.89% CAGR during the forecast period from 2024 to 2032.

    Which region held the largest market share in the Antifungal Treatment Market?

    The North America region market held the largest market share in the Antifungal Treatment Market.

    Who are the key players in the Antifungal Treatment Market?

    The key players include Pfizer Inc (US), Johnson & Johnson Services, Inc (US), Bayer AG (Germany), Novartis AG (Switzerland), Abbott Laboraotories, Inc. (US), Merck KGaA (Germany), Gilead Sciences, Inc (US), Cipla, Inc. (India), Sanofi S.A. (France), and GlaxoSmithKline Plc (UK).

    Which drug class led the Antifungal Treatment Market?

    The azoles solution drug class segment led the Antifungal Treatment Market in 2022.

    Which route of administration had the largest market share in the Antifungal Treatment Market?

    Topical route of administration segment had the largest market in 2022 with a market share around 49%.

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